目的 探讨老年性玻璃体切除联合白内障手术治疗增生性糖尿病视网膜病变患者家庭关怀度与自我感受负担的相关性.方法 选取2014年1月至2017年10月我院行老年性玻璃体切除联合白内障手术治疗的增生性糖尿病视网膜病变患者64例,采用家庭关怀度量表、自我感受负担量表对患者进行调查,分析该类患者的家庭关怀及自我感受负担现状,比较不同程度自我感受负担患者的家庭关怀度评分,采用Pear-son相关分析自我感受负担评分与家庭关怀度评分的相关性.结果 行老年性玻璃体切除联合白内障手术治疗的增生性糖尿病视网膜病变患者的家庭关怀度评分为(7.41±1.52)分,自我感受负担量表评分为(32.69±4.17)分;不同程度自我感受负担患者的家庭关怀度评分及各维度评分比较差异有统计学意义(P<0.05);自我感受负担量表评分与家庭关怀度评分及各维度评分呈负相关(P<0.05).结论 老年性玻璃体切除联合白内障手术治疗增生性糖尿病视网膜病变患者的自我感受负担普遍较重,通过提高患者的家庭关怀度,如亲密度、适应度、情感度等,有助于减轻患者的自我感受负担.

目的 探讨超声乳化术联合小梁切除术治疗白内障合并青光眼的疗效.方法 100例白内障合并青光眼患者作为研究对象,按照随机数字表法分为对照组和观察组,每组50例.对照组患者采取小梁切除术,观察组采取超声乳化联合小梁切除术.观察比较两组患者疗前后的眼压、裸眼视力、中央前房深度、临床疗效及并发症发生情况.结果 两组患者治疗后上述各项视力指标均明显改善,且观察组眼压、裸眼视力、中央前房深度分别为(12.892±4.262)mm Hg(1 mm Hg=0.133 kPa)、(0.352±0.033)、(2.782±0.325)mm,均明显优于对照组的(21.856±3.682)mm Hg、(0.235±0.075)、(2.345±0.382)mm,差异均有统计学意义(P<0.05).观察组患者治疗总有效率为94.00％(47/50),明显高于对照组的80.00％(40/50),差异有统计学意义(χ2=4.332,P=0.037<0.05).观察组患者的并发症发生率为6.00％(3/50),明显低于对照组的28.00％(14/50),差异有统计学意义(χ2=8.575,P=0.003<0.05).结论 超声乳化术联合小梁切除术治疗白内障合并青光眼的疗效显著,安全性较高,值得临床推广应用.

目的 研究分析深圳地区青少年干眼症的发病机制、症状特点以及临床治疗方法 .方法 30600例深圳地区青少年作为研究对象,根据生长发育年龄分为A组(13~15周岁)、B组(16~18周岁)、C组(19~21周岁)、D组(22~24周岁),均为7650例.分别对其开展干眼症的流行病学问卷调查、宣教以及相关眼部检查,统计分析干眼症青少年不同年龄段、用眼时间以及空气环境特点.结果 30600例干眼症患者中有3375例,患病率为11.03%;青少年干眼症发病率随年龄的升高而升高,四组比较,差异具有统计学意义(P<0.05).干眼症症状主要表现为眼睛干涩、异物感、烧灼感、流泪、眼红、畏光、痒、视物疲劳、模糊以及视力下降等.用眼时间、屈光不正、视觉终端暴露、滥用降压药物及滴眼液以及空气污染是青少年干眼症发病的高危因素.结论 深圳地区青少年干眼症的发病率居高不下,防治情势十分严峻,应根据不同人群的特点,积极采取治疗干预措施,从而有效预防干眼症的发生.

目的：研究分析玻璃体内注射康柏西普联合激光治疗视网膜分支静脉阻塞合并黄斑囊性水肿的临床疗效。方法60例视网膜分支静脉阻塞合并黄斑囊性水肿患者，随机分成对照组(给予视网膜激光进行光凝治疗)及观察组(在对照组基础上联合采用玻璃体内注射康柏西普治疗)，各30例。比较两组患者治疗前后的黄斑中心凹视网膜厚度(CMT)、最佳矫正视力(BCVA)水平。结果治疗后，两组患者CMT、BCVA水平均较治疗前改善，且观察组[(209.48±109.74)μm、(0.31±0.02)]改善程度优于对照组[(469.21±101.32)μm、(0.23±0.03)]，差异具有统计学意义(P<0.05)。结论玻璃体内注射康柏西普联合激光治疗视网膜分支静脉阻塞合并黄斑囊性水肿能够有效减轻黄斑囊性水肿，提高视力水平。

Objective To study changes and significance of hemorheology and enfothelin-1(ET-1)of patients with primary glaucoma.Methods 84 cases with primary glaucoma in our hospital were collected,were randomly divided into group A (mild vision damage group),group B (moderate vision damage group)and group C (severe vision damage group),and 28 senile cataract patients were collected as group D (control group).Hemorheology and ET-1 of the four groups were compared.Results Hemorheology indexes and ET-1 levels of group A,group B and group C were signifi-cantly higher than group D (P <0.05).Whole blood viscosity and ET-1 of group A1,group B1 and group C1 were sig-nificantly higher than group A2,group B2 and group C2(P <0.05).Blood plasma viscosity,erythrocyte deposited and fibrinogen level of group A1,group B1 and group C1 were higher than them of group A2,group B2 and group C2,but there was no statistically significant difference(P >0.05).Conclusion Changes of hemorheology of patients with pri-mary glaucoma can affect the optic nerve.Increased levels of ET-1 can participate in the process of vascular dysfunc-tion.Both are the important pathogenesis of primary glaucoma.

目的 探讨翼状胬肉大小与角膜地形图间的相关性,总结手术切除翼状胬肉的临床价值.方法 选取2010年1月-2013年1月间于我院诊治的原发性翼状胬肉患者100例进行回顾性分析.结果 P-屈光度明显低于角膜平均屈光度、中心屈光度及最平径值,组间差异在统计学上有意义(P＜0.05);胬肉横径及竖径均与散光度呈正相关性,而其p-距离则与散光度呈负相关性;术后患者P-屈光度及散光度指标均明显优于术前各相应指标,术前、后差异在统计学上有意义(P＜0.05);翼状胬肉横径与散光度呈正相关性,且手术时胬肉横径越短,患者术后散光度值恢复效果越佳.结论 翼状胬肉大小与角膜地形图具有一定的相关性,手术治疗可改善患者角膜屈光度,且手术时间宜早.

Objective To explore the quality of life (QOL) status and psychology characteristics of patients with Sudden Deafness. Methods One hundred and thirty-five patients with sudden deafness were enrolled by random,their QOL scores were assessed by using Chinese version of the SF-36,their psychological scores were assessed by filling out SAS,SDS. The demographic characteristics of sudden deafness group and health group were compared. Results Compared with health group,there was a significant impairment in all QOL dimensions in patients with allergic rhinitis(P < 0.05).Especially in mental health,role limitations due to emotional problems,vitality,general health perceptions,role limitations due to physical health dimensions. SAS and SDS scores of a sudden deafness patients had significant increase compared with norm(P<0.001).Conclusion Sudden deafness patients experience significant impairment in QOL and they have evident anxiety and depression.

目的探讨内镜鼻窦开放术后使用纳吸绵鼻腔填塞止血材料的临床疗效观察。方法将98例鼻腔鼻窦手术患者随机分为两组，一组采用纳吸绵止血材料填塞止血；另一组采用Merocel高膨胀材料填塞止血，比较两组患者在术后48h内、抽取填塞物时的临床症状及取出填塞物后鼻腔的局部表现。结果使用纳吸绵组术后48h内头痛、鼻痛及鼻渗/出血发生率低于Merocel高膨胀材料组（P＜0.05），抽取鼻腔填塞物时疼痛率及出血率明显低于Merocel高膨胀材料组（P＜0.01），术后鼻腔恢复通气天数、术腔上皮化时间较短，发生鼻腔粘连数、术腔肉芽、囊泡数均比Merocel高膨胀材料组少（P＜0.05）。结论纳吸绵疗效确切，不良反应少，病人痛苦少，是理想的鼻腔填塞材料。

Objectives To evaluate the feasibility of myeloperoxidase(MPO) served as diagnostic and prognostic markers in the course of coronary artery disease.Methods MPO,cardiac troponin I(TnI),creatine kinase-MB(CK-MB),Creactive protein(CRP),fibrinogen and D-dimers(DD) were measured by enzyme immunoassay(Bio-Check) and diagnostic sensitivities of them were compared.Results Serum concentration of MPO increased systematically with the advancement of coronary artery disease.As diagnostic and prognostic markers for coronary artery disease,the sensitivity of MPO was higher than those of TnI,CK-MB,CRP,fibrinogen and DD.Conclusions MPO may serve as attractive diagnostic and prognostic markers in the assessment of the risk for unstable atheroma in the course of coronary artery disease.