A series of hitherto unreported μ-oxy-bis[triphenylantimony(V)]dicarboxylates and μ-oxy-bis[triphenylantimony(V)] chlorocarboxylates of general formula Ph3Sb(L)-O-Sb(L)Ph3 and Ph3Sb(Cl)-O-Sb(L)Ph3, respectively have been synthesized by the metathetical reaction of μ-oxybis-[triphenylantimony(V)]dichloride and silver salts of corresponding carboxylic acids in 1:2 and 1:1 molar ratio [where L = thiosalicyclic acid, p-nitrobenzoic acid, p-aminobenzoic acid, p-fluorobenzoic acid, o-chlorobenzoic acid]. The newly isolated antimony carboxylates have been identified on the basis of melting points, elemental analysis, FT-IR, 1H NMR,13C NMR, 19F NMR. The molecular weight and conductivity data indicate the monomeric and non-electrolytic behaviour in solution. Compounds have been evaluated for their antifungal and antibacterial activity.

Tetra & Penta-coordinate neutral adducts (C6H5)2 SbCl.L and (C6H5)SbCl2.2L [L= α, β & γ-picoline, HMPA, Ph3PO, TU, Py] have been synthesized. Molecular adducts are monomeric in benzene and non- electrolyte in acetonitrile. IR spectra and conductance measurement suggest the presence of coordination of Oxygen, Nitrogen, and Sulphur donar ligands in adducts. Spectroscopic data conform to the requirement of tetra coordinate and penta coordinate configuration for neutral adducts.

Detailed examples of μ-oxy-bis[triphenylantimony(V)] carboxylate preparation are described below and the conditions Several unknown μ-oxybis[triphenylantimony]dicarboxylates and μ-oxy bis[triphenylantimony]chloro-carboxylates of the general formula Ph3Sb(L)-O-Sb(L)Ph3 and Ph3Sb(Cl)-O-Sb (L)Ph3, respectively have been synthesised by the metathetical reactions of μ-oxybis[triphenylantimony]dichloride reactions and silver salts of corresponding carboxylic acids in 1:2 and 1:1 ratio [where L= 2-pyrazine carboxylic acid, p-methoxy mandelic acid, salicylic acid, benzillic acid and p(trifluoromethyl)mandelic acid)]. The compounds were non-effective against the tested soil born fungi. This shows that the compounds do not interfere with soil fungal flora. They show compatibility with the beneficial bio-fungicide. Trichoderma at least up to 100 g/ml. The newly synthesized antimony derivatives have been characterized on the basis of melting point, elemental analysis, IR 1 H and 13 C NMR spectra. The molecular weight and conductivity data indicate the monomeric and non-electrolytic behavior in solution.

Perfluorophenyl antimony(III) and antimony(V) chlorides experimentally scanned earlier for antifungal activity against Aspergillus flavus and Aspergillus niger, and insecticidal activity viz., contact toxicity, stomach toxicity, antifeedant activity and acaricidal activity against Spodoptera litura and Tetranychus urticae of mites. These activities have been theoretically predicted by DFT method using B88-LYP GGA energy functional with DZVP basis set. Comparison of the experimental values and the values obtained by theoretical calculations has been presented pictorially and shows close resemblance.

Several unknown mu-oxybis[triphenylbismuth]dicarboxylates and mu-oxy-bis[triphenylbismuth]chloro-carboxylates of the general formula Ph3Bi(L)-O-Bi(L)Ph-3 and Ph3Bi(Cl)-O-Bi(L) Ph-3, respectively have been synthesised by the metathetical reactions of mu-oxybis[triphenylbismuth]dichloride reactions and silver salts of corresponding carboxylic acids in 1:2 and 1:1 ratio [where L=2-pyrazine carboxylic acid, p-methoxy mandelic acid, salicylic acid, benzillic acid and p-(trifluoromethyl)mandelic acid)]. The newly synthesized bismuth derivatives have been characterized on the basis of melting point, elemental analysis, IR H-I and C-13 NMR spectra. The molecular weight and conductivity data indicate the monomeric and non electrolytic behaviour in solution.

13 C NMR spectroscopy, molecular weight and conductance measurements. The newly synthesized derivatives are monomeric in benzene and non ionic in acetonitrile. In the solid state a penta coordinate dispensation around bismuth having monodentate OCOR group indicated on the basis of spectroscopic and physic chemical datas.

A series of tris (α-naphthyl) bismuth (V) carboxylates (α-C10H7)3Bi(OCOR)2 where OCOR = p-trifluoromethyl mandelate, pmethoxy mandelate, salicylate, 2pyrazine carboxylate, mandelate have been synthesised and characterised by solid state infrared, H and C NMR spectroscopy, molecular weight and conductance measurements. The newly synthesized derivatives are monomeric in benzene and non ionic in acetonitrile. In the solid state a penta coordinate dispensation around bismuth having monodentate OCOR group indicated on the basis of spectroscopic and physic chemical datas. Keywords— Tris (α-naphthyl) bismuth carboxylates, IR, H NMR, CNMR spectra, monomeric, non ionic ——————————  ——————————

A series of new tri and tetra-organoantimony (V) aryloxyacetates of the general formula R3Sb(OCOCH 2OR') 2; and R4Sb(OCOCH2OR') (where R = p-OCH 3C 6H4-, C 6H5- & R' = p-CH3C6H4-, m-CH 3C6H 4-, o-CH3C 6H4-, β-C10H 7-, o-ClC 6H 4-), have been synthesised and characterised. These complexes are monomeric in benzene and non-electrolyte in acetonitrile. IR, NMR spectral data suggest the hepta-coordination with weak secondary interaction in between antimony and carbonyl oxygen of aryloxyacetate ligands.

A series of sterically hindered μ-oxo bis [tricyclohexylantimony (V)] carboxylates [(cyclo-C6H11)3Sb-O-Sb(cycloC6H11)3](OCOR)2 where -OCOR = p-trifluoromethyl mandelate, p-methoxy mandelate, salicyclate, 2pyrazine carboxylate, mandelate has been synthesised and characterised by solid state infrared, H , Fand C NMR spectroscopy, molecular weight and conductance measurements. The newly synthesized derivatives are monomeric in benzene and non ionic in acetonitrile with pentacoordination dispensation around antimony. Keywords—μ-oxo bis [tricyclohexylantimony (V)] carboxylates, halocarboxylates, IR, H, F NMR, CNMR spectra, monomeric, non ionic. ——————————  ——————————

Interactions of HgX2 (X = Cl, Br, I, SCN, CN, NCO), SbCl3, TeCl4 and PhTeCl3 with (p-FC6H4)(3)Sn-O-Sn(p-FC6H4)(3) at room temperature have been found to proceed with the simultaneous cleavage of Sn-O and Sn-C bonds, invariably yielding (p-FC6H4)(2)SnO, (p-FC6H4)(3)SnX and the corresponding organo-mercury, -antimony and -tellurium derivatives. The course of the reactions suggests the instability of the Sn-O-M (M = Hg, Sb, Te) system.

Halo and pseudohalo demetallation reactions of higher valent pentaphenyl –arsenic and antimony and, tetrapolyfluorophenyl tin have been carried out employing halogens X2 (X = Br, I) interhalogens IX (X = Cl, Br), ICl3, pseudohalogen (SCN)2, halo-pseudohalogens XSCN (X = Cl, Br) IN3, INCO and, metallic halides TeCl4 and (NH4)2PbCl6. Reaction of (C6H5)5M (M= As,Sb) with these electrophiles afforded corresponding arsonium and stibonium derivatives (C6H5)4MX while reactions of tetrafluorophenyl tin (C6F5)4Sn with halogens and interhalogens yielded corresponding (C6F5)nSnX4-n (X = Cl, Br n = 2,3) derivatives depending upon the molar ratio of reactants and the reaction conditions. The products have been identified by m.p. elemental analysis and spectroscopic data.

Several hitherto to unknown µ-oxybis[triarylantimony(V)]dicarboxylates & µ-oxybis[triarylantimony]halo-carboxylates of the general formula R3Sb(L)-O-Sb(L)R3 & R3Sb(Cl)-O-Sb(L)R3 respectively have been synthesised by the metathetical reactions of µ-oxybis(triarylantimony)dichloride reactions and silver salts of corresponding carboxylic acids in 1:2 & 1:1 ratio [where L= 2-pyrazine carboxylic acid, p-methoxy medallic acid, salicylic acid, benzillic acid, )]. The newly synthesised antimony derivatives have been characterised on the basis of melting point, elemental analysis, IR IH & 13C NMR spectra. The molecular weight & conductivity data indicate the monomeric & non electrolytic behaviour in solution, these have been found to exhibit moderate to significant antimicrobial activity.

Interactions of HgX2 (X = Cl, Br, I, SCN, CN, NCO), SbCl3, TeCl4, and PhTeCl3 with Ph3Sn-O-SiPh3 at room temperature have been found to proceed with the simultaneous cleavage of Sn-O and Si-O bonds, invariably yielding Ph2SnO, Ph3SiX, and the corresponding organo-mercury, -antimony, and -tellurium derivatives. The course of the reactions suggests the instability of the Sn-O-M (M = Hg, Sb, Te) system.

A series of hitherto unreported solid salts of penta-coordinated cations of the general formula [R2SbL3](3+), where R = C6H5, P-ClC6H4, p-CH3C6H4, p-(CH3O)C6H4; L = DMSO, Ph3AsO, Py-N-oxide, DMF, alpha-, beta-, and gamma-picoline have been prepared in the presence of tetraphenyl and tetrafluoro-borate counterions. The, complexes have been formulated and characterized on the basis of elemental analyses, molar conductances, molecular weights, and solid state IR and solution state H-1 NMR spectral data. The physico-chemical data are consistent with five-coordinate antimony complexes.

Interaction of metallic salts (M = Hg, Sb, and Te) with bis(triorganotin)oxide, (R3Sn)(2)O, where (R = C6H5, p-CH3C6H4, and cyclo-C6H11) at room temperature proceeded with the simultaneous cleavage of the Sn-C and Sn-O bonds, invariably yielding R2SnO along with other products. Thus the treatment of HgX2 (X = Cl, CN, SCN) with (R3Sn)(2)O resulted in the formation of polymeric diorganotin oxide R2SnO along with R3SnX and RHgX derivatives. The reaction of SbCl3 with (R3Sn)(2)O was found to give R2SnO, R3SnCl, and RSbCl2, whereas interaction with SbCl5 provided R2SnO, R2SnCl2, and R2SbCl3. Treatment of TeCl4 with (R3Sn)(2)O provided R2SnO, R3SnCl, and RTeCl3 at room temperature. At reflux temperature, reaction of PhTeCl3 with (R3Sn)(2)O yielded R2SnO, R3SnCl, and mixed diorganotellurium dichloride, RPhTeCl2. The course of reaction indicated the instability of Sn-O-Sn system proceeding via a four-centered mechanism, providing organometallic compounds in profitable yield. (C) 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:278-283, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10. 1002/hc.20547

Benzoxazole derivatives show various types of biological properties such as antiviral, antineoplastic, anti-HIV-1, antitubercular, anthelmintic, antimicrobial, and antifungal activities. In the last few years 2-substituted benzoxazole derivatives have been studied extensively for their antitumor, antiviral, and antimicrobial activities. In an effort to identify new candidates that may be of value in designing new, potent, selective, and less toxic anticancer, antiviral, and/or antimicrobial agents, we synthesized 2-[(arylhydrazono) cyanomethyl]-5-chloro benzoxazoles (II), 2-[(arylidene)cyanomethyl]-5-halo benzoxazoles (III), and 2-[(cycloalkylidine)cyanomethyl]-5-chlorobenzoxazoles (IV), and tested them for anticancer, antifungal, and antibacterial activities. Some of these (compounds 11, 14) were found to possess anticancer activity and remarkable antifungal as well as antibacterial activities.

Several hitherto unreported pentacoordinated tetraphenylstibonium(V) carboxylates of general formula (C6H5)(4)SbL, where L = o-OHC6H5 COO-, (C6H5)(2)C(OH)COO-, 2-(6-OCH3C10H6)CH (CH3)COO-, ArCH(OH)COO- (Ar=C6H5, p-CF3-[GRAPHICS]C6H4, and p-OCH3C6H4), have been prepared and characterized by elemental analysis, solid state IR, H-1 NMR, and C-13 NMR spectra, conductivity, and molecular weight measurements. Spectroscopic data together with solution phase studies conform to the requirement of triagonalbipyramidal configuration for these compounds. They were tested for in vitro antifungal (against Aspergillus flavus and Aspergillus niger) and antibacterial (against Staphylococcus aureus and Klebsiella pneumoniae) activities. The in vitro antitumor activity of all stibonium carboxylates was examined against MCF-7 cell line. A few of them were found to exhibit moderate to significant biological activity. (C) 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:688-693, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20498