Objectives: To investigate selected perceptual determinants of pharmacy students' expected job satisfaction. Such determinants included: (1) Students' perceptions of the effects of demands upon pharmacists' job satisfaction, (2) students' perceptions of the effects of other health care providers' demands upon pharmacists' job satisfaction, and (3) students' perceived professional image upon pharmacists' job satisfaction.Material and methods: This research makes use of the personal survey questionnaire method for measuring perceptions of job satisfaction. Subjects for the study were fifth-year professional students in an entry-level Doctor of Pharmacy program class of 192 students. Surveys were returned by 107 students (55.7% of those asked to participate), of which 103 were complete enough to use in the analysis using job satisfaction assessment.Results: Stepwise linear regression within this sample found job satisfaction perceptions of students were best predicted by their beliefs in the encounters they will have with physicians and other health care providers (p = .0016) and by the professional image they perceive the pharmacy profession to have (p = .0015). Patient demands had no statistically significant predictive value in this sample of students' perceptual job satisfaction scores on overall job satisfaction (p = .2496).Conclusion: These results have important implications for human resource managers and administrators of pharmaceutical care delivery systems whose major concerns are to retain as well as recruit sufficient numbers of young job seekers who are pursuing pharmacy as a career. (C) 2011 Elsevier Inc. All rights reserved.

Figure 1. A polycyclic, papular eruption on the face. A 24-year-old transgender woman with Treacher-Collins syndrome (mandibulofacial dysostosis) and AIDS (CD4 + cell count, 151 cells/mm 3) presented with a 1-month history of a pruritic, mildly erythematous, polycyclic papular eruption distributed diffusely over her face. She had no history of any similar eruptions and no history of facial implants or facial surgeries for Treacher-Collins syndrome. She denied fever, chills, or other systemic symptoms and had no contact with plants, metals, or new cosmetics. The remaining findings of the review of systems were unremarkable. The patient had been sexually active within the previous 6 months, often without barrier protection. She had received a diagnosis of AIDS 4 years earlier and had been receiving continuous antiretroviral therapy , with the exception of a break in therapy just prior to the onset of the skin eruption. The patient had no recent travel

CORRESPONDENCEdaily dialysis [5].Thirty-two years after this first extended daily dialysis, Peter Kramer introduced continuous arteriovenous hemofiltration as a method of "fluid withdrawal in over-hydrated patients resistant to diuretics" which enabled the physician to "ensure a negative fluid balance even at a mean blood pressure of only 60 mm Hg" [6], which would not have been able by using intermittent hemodialysis in this patient population at the time.Therefore, the statement by Mushatt and colleagues that "the original extended dialysis modality was continuous arteriovenous hemofiltration" is incorrect.

Slow extended daily dialysis (SLEDD) is the newest form of dialysis that is being used increasingly to replace continuous venovenous hemodialysis (CVVHD) for critically ill patients; it is less expensive to administer and has similar safety for patients who are prone to hemodynamic instability. Unfortunately, there are limited data regarding the appropriate dosing of antimicrobial agents for patients undergoing SLEDD. Furthermore, many nonnephrologists are not familiar with the differences between SLEDD, other continuous renal replacement therapies-for example, CVVHD-and routine hemodialysis. Thus, there is potential for inaccurate and, at worst, inadequate dosing of critical antimicrobial agents for this patient population. We review the available pharmacokinetic data on SLEDD and give preliminary recommendations for how to approach dosing in this situation.

Current evidence suggests that controlling antibiotic resistance requires the monitoring of both susceptibility trends and antimicrobial usage within specific patient-care areas of the hospital. To assess the differences between antimicrobial usage-versus-susceptibility relationships found in the hospital and those relationships found in specific patient-care areas, susceptibility and antimicrobial usage data collected over a 5-year period (1992-1996) at the Medical University of South Carolina were analyzed. For each area, the relationship between drug use and susceptibility was analyzed for 8 gram-negative organisms with respect to 19 different agents and for 3 staphylococci with respect to 10 agents with use of simple linear regression. The relationships found in the hospital had a poorer overall agreement with the relationships found in the intensive care units (ICUs; <20%) than they did with the relationships found in the non-ICUs ( approximately 65%). Surveillance should include both susceptibility and drug usage patterns in individual areas within an institution.