The chromatographic behavior of a series of tosylated xylitol derivatives has been studied on silica gel and on C-8- and C-18-modified silica gel layers with, respectively, binary nonaqueous and aqueous mobile phases. The slopes and intercepts of the linear relationships between the retention constant (R-M) and the logarithm of the volume fraction of the polar component of the nonaqueous mobile phase, and of the volume fraction of organic component of the aqueous-organic mobile phase, have been calculated and are discussed in relation to the properties of the solute and of the mobile and stationary phases. The retention and relative retention of compounds depend largely on the retention behavior of their substituents.

The retention behavior of a series of steroids in liquid - solid chromatography has been studied as a function of the concentration of the diluent in ternary nonaqueous mobile phases. The relationship between the retention constant R(M) and the concentration of a diluent in the mobile phase was linear, with the slope values depending on the molecular structures of the compounds.