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1VIOMYCIN 1. MITT. STRUKTUR DES GUANIDIN ENTHALTENDEN TEILS 2. MITT. STRUKTUR DES CHROMOPHORS

B. W. Bycroft,L. R. Croft, A. W. Johnson, T. Webb, D. Cameron,A. Hassanali-Walji

1972

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2ChemInform Abstract: VIOMYCIN 1. MITT. STRUKTUR DES GUANIDIN ENTHALTENDEN TEILS 2. MITT. STRUKTUR DES CHROMOPHORS

B. W. BYCROFT,L. R. CROFT,A. W. JOHNSON,T. WEBB,D. CAMERON,A. HASSANALI‐WALJI

Chemischer InformationsdienstVolume 3, Issue 22 Isocyclic Compounds ChemInform Abstract: VIOMYCIN 1. MITT. STRUKTUR DES GUANIDIN ENTHALTENDEN TEILS 2. MITT. STRUKTUR DES CHROMOPHORS B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorA. HASSANALI-WALJI, A. HASSANALI-WALJISearch for more papers by this author B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorA. HASSANALI-WALJI, A. HASSANALI-WALJISearch for more papers by this author First published: May 30, 1972 https://doi.org/10.1002/chin.197222440AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume3, Issue22May 30, 1972 RelatedInformation

1972Chemischer Informationsdienst

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3Viomycin. Part II. the Structure of the Chromophore

B W Bycroft,D Cameron,L R Croft,A Hassanali-Walji,A W Johnson,T Webb

The chromophoric unit of viomycin is shown to be the monoureide of C-formylglycine, which is present in peptide combination. Hydrogenolysis of viomycin followed by hydrolysis yields alanine, which is not present in viomycin hydrolysates and which is derived from the chromophore. Other reactions of viomycin which involve the chromophore are discussed. The rate of evolution of urea during mild hydrolyses of viomycin is shown to correspond to the rate of loss of the chromophore; the unstable product, deureidoviomycin, can be recombined with urea to reconstitute the antibiotic.

1972Journal of the Chemical Society Perkin transactions 1（1972）引用：23

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4Viomycin .2. Structure Of Chromophore

B. W. Bycroft,D. Cameron,L. R. Croft,A. Hassanali-Walji,A. W. Johnson,T. Webb

1972JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1（1972）引用：10

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5Viomycin. Part I. the Structure of the Guanidine-Containing Unit

B W Bycroft,L R Croft,A W Johnson,T Webb

Viomycidine, a bicyclic guanidino-amino-acid obtained from viomycin by acidic hydrolysis, is shown to be an artefact derived by cyclisation from a monocyclic guanidino-carbinol unit. Several reactions of viomycin find close analogies in the chemistry of tetrodotoxin, which also contains a guanidino-carbinol fragment. The structural relationship between viomycin and capreomycin has been established.

1972Journal of the Chemical Society Perkin transactions I/Journal of the Chemical Society Perkin transac...（1972）引用：13

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6Viomycin .1. Structure of Guanidine-Containing Unit

BW BYCROFT,LR CROFT,T WEBB,AW JOHNSON

1972JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1（1972）引用：17

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7The Total Structure of Viomycin, a Tuberculostatic Peptide Antibiotic

B. W. Bycroft,D. Cameron,L. R. Croft,A. Hassanali-Walji,A. W. Johnson,T. Webb

Die Struktur von Viomycin wird durch seine Zerfallseigenschaften bestimmt und das Vorhandensein von Guanidin-Carbinol sowie von Dehydroserin oder Formylglycin bestätigt.

1971Experientia（1971）引用：43

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8ChemInform Abstract: TOTALSTRUKTUR VON CAPREOMYCIN IB, EINEM TUBERCULOSTATISCHEN PEPTID‐ANTIBIOTICUM

B. W. BYCROFT,D. CAMERON,L. R. CROFT, A. HASSANALI, A. WALJI,A. W. JOHNSON,T. WEBB

Chemischer Informationsdienst. Organische ChemieVolume 2, Issue 36 Natural Products ChemInform Abstract: TOTALSTRUKTUR VON CAPREOMYCIN IB, EINEM TUBERCULOSTATISCHEN PEPTID-ANTIBIOTICUM B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. HASSANALI, A. HASSANALISearch for more papers by this authorA. WALJI, A. WALJISearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this author B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. HASSANALI, A. HASSANALISearch for more papers by this authorA. WALJI, A. WALJISearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this author First published: September 7, 1971 https://doi.org/10.1002/chin.197136393Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume2, Issue36September 7, 1971 RelatedInformation

1971Chemischer Informationsdienst Organische Chemie（1971）

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9Total Structure of Capreomycin IB, a Tuberculostatic Peptide Antibiotic.

BW BYCROFT,D CAMERON,LR CROFT, HASSANAL.A,AW JOHNSON,T WEBB

Analytical data suggest that the capreomycins and viomycin are members of the same closely related family of antibiotics.

1971Nature（1971）引用：58

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10ChemInform Abstract: TOTALSTRUKTUR VON VIOMYCIN, EINEM TUBERKULOSTATISCHEN PEPTIDANTIBIOTICUM

B. W. BYCROFT,D. CAMERON,L. R. CROFT,A. HASSANALI‐WALJI,A. W. JOHNSON,T. WEBB

Chemischer Informationsdienst. Organische ChemieVolume 2, Issue 32 Organic Dyes ChemInform Abstract: TOTALSTRUKTUR VON VIOMYCIN, EINEM TUBERKULOSTATISCHEN PEPTIDANTIBIOTICUM B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. HASSANALI-WALJI, A. HASSANALI-WALJISearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this author B. W. BYCROFT, B. W. BYCROFTSearch for more papers by this authorD. CAMERON, D. CAMERONSearch for more papers by this authorL. R. CROFT, L. R. CROFTSearch for more papers by this authorA. HASSANALI-WALJI, A. HASSANALI-WALJISearch for more papers by this authorA. W. JOHNSON, A. W. JOHNSONSearch for more papers by this authorT. WEBB, T. WEBBSearch for more papers by this author First published: August 10, 1971 https://doi.org/10.1002/chin.197132335Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume2, Issue32August 10, 1971 RelatedInformation

1971Chemischer Informationsdienst Organische Chemie（1971）

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11The Structure, Stereochemistry and Reactions of the Guanidine Moiety of Viomycin.

BW BYCROFT,LR CROFT,AW JOHNSON,T WEBB

Recently we presented evidence to suggest that the tuberculostatic antibiotic viomycin contains the unit I1}.More recently several papers2'3>4) have lent support to this

1969The Journal of Antibiotics（1969）引用：21

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12The Chromophore and Partial Structure of Viomycin