The reaction of 2,4-diacetyl-5-hydroxy-5-methyl-3-phenylcyclohexanone-1 with phenylhydrazine is conducted, and the crystal structures of its products, 1-(6-hydroxy-3,6-dimethyl)-2,4-diphenyl-4,5,6,7-tetrahydro-2H-indazol-5-yl)ethane-1-one and 1-(2-hydroxy-2-methyl-6-phenyl-4-(2-phenylhydrazono)-5-(1-(2-henylhydrazono)ethyl)cyclohexyl)ethane-1-one, are determined by single crystal XRD.

The 4H-pyran ring of the title compound, C17H16N2O2, is nearly planar [maximum deviation = 0.077 (2) Å] and the cyclohexene ring adopts a flattened chair conformation [puckering parameters:QT= 0.435 (2) Å, θ = 122.0 (3)° and φ = 53.5 (3)°]. The 4H-pyran ring is almost perpendicular to the benzene ring [dihedral angle = 87.23 (8)°] and is almost coplanar with the mean plane of the cyclohexene ring [dihedral angle = 8.01 (8)°]. In the crystal, inversion-related molecules are linked by pairs of intermolecular N—H...N hydrogen bonds, forming inversion dimers withR22(12) ring motifs. These dimers are further connected by N—H...O and C—H...N hydrogen bonds, forming a layer structure extending parallel to (0-12). Molecules within the layers interact with each otherviaC—H...π interactions.

Two major classes of compounds of hydroacridinones and hydroxanthenones have been synthesized in a satisfactory yield via three component condensation reaction of amino alcohols, dimedone and aromatic aldehydes. The applied amino alcohols acted as reactant in one reaction to afford 3,6,6-tetramethyl-,2,3,4,5,6,7,8,9,10-decahydroacridine1,8-diones and acted as catalyst in the other reaction to afford 1,8-dioxooctahydroxanthenones. The structure of products has been characterized by X-ray crystal structural analyses, C-NMR, H-NMR, IR and Mass spectra.

Microwave irradiation of three components of primar y amino alcohols 1, acetylacetone and aromatic aldehydes 2 afforded the formation of amino-cyclohexene derivat ives 3 in a very good yield (average 85%). The products h ave been characterized by HNMR,CNMR, IR and mass spectra.

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

The alkylation of some representatives of β-dicarbonyl compounds by 1,4-dibromo-2-butene and ethyl 2,3-dibromopropionate was investigated.

By condensation of ethyl ether of 2-oxoindoline-3-glyoxyle acids with 2-aminothiol the method of synthes of indolinesubstituted 1, 4-tetrahydrothiazin-2-nowe been worked out