A study of the reaction of phenyl magnesium bromide with various N-(cyanomethyl)oxazolidines showed that product formation (essentially 3-imidazolines and 2-aminomorpholines) is highly sensitive to the substitution pattern and stereochemistry, and appears to involve initial complexation of the Grignard reagent to ring-oxygen. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
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