Addition of an aldehyde and zinc chloride to a cyclobutanone enolate, prepared by the reaction of an α-chlorocyclobutanone with dimethylcopperlithium, gave an aldol adduct in good yield.
A method was devised for the recovery of dialkylnitrosamines in the parts/109 level. The procedure involved the addition of K2CO3 to water samples and concentration of the nitroso compounds on Amberlite XAD-2 resin. The recoveries of dimethyl- and diethylnitrosamines were greater than 90%