Diagnostic reference levels (DRLs) have been proven to be a useful tool for optimizing patient radiation exposure. National DRLs (NDRLs) are defined based on data from a representative sample of the healthcare facilities in a particular country. This project presents the survey to update the NDRLs for cardiac interventional procedures in Switzerland. Healthcare facilities performing cardiac procedures in Switzerland were asked to provide radiation dose data for adult cardiac interventional procedures performed over the course of one year. The dataset included the procedure name and the corresponding air kerma area product, air kerma at the reference point, fluoroscopy time and number of cine acquisitions. Thirty-five healthcare facilities (95% of the total) provided data. The procedures were grouped into 11 electrophysiology procedures, 4 cardiac catheterization procedures, and 3 structural heart procedures. For each healthcare facility and radiation quantity, the median values were calculated. Updated NDRLs were determined as the 75th percentile of the distribution of these median values. For example, the updated NDRL for air kerma area product was set at 24 Gy∙cm2 for coronary angiography and at 2 Gy∙cm2 for pacemaker implantation, reflecting a substantial reduction from the prior NDRL values of 50 and 30 Gy∙cm2, respectively. These new NDRL values are substantially lower than the previous ones, highlighting the importance of conducting regular updates to accommodate continuous patient dose optimization of and technological advancements.
OBJECTIVES:The study aims to compare recurrent CT imaging practices across multiple centres in Europe using incidence and prevalence metrics, and to test the feasibility of establishing a new benchmarking tool for recurrent imaging practice across facilities. METHODS:Data of CT exposure were collected in 31 facilities from 18 European countries. The incidence proportion in a single year (I 100; 1), cumulative incidence over 3 consecutive years (I 100; 3), and 3-year prevalence proportion (P 100; 3) of patients with cumulative effective dose (CED) ≥ 100 mSv were calculated, and statistical analyses performed to correlate them with other relevant indicators. The reference year for data collection was 2023, and the 3-year period covered 2022-2024. RESULTS:The database included 711,749 patients in the reference year who underwent 1,658,246 CT exams, with an average number of 1.5 ± 0.6 CT exams per patient in the reference year and 2.4 ± 0.6 exams per patient in three years. Across facilities, I 100; 1 ranged from 0 to 2.9%, I 100; 3 from 0 to 8.6%, and P 100; 3 ranged from 0% to 4.4%. Strong linear correlation was found between the 3rd quartile values of yearly CED and I 100; 1. Multiple linear relationship was identified between I 100; 3, 3rd quartile of yearly CED and percentage of recurrent patients. The facilities' 3rd quartiles of yearly CED varied between 7.5 and 29.5 mSv, and the 75th percentile of their distribution was 17.6 mSv, which are lower than in previous studies. CONCLUSION:Incidence proportion is recommended as the primary metric for future studies assessing recurrent imaging, since prevalence indexes substantially underestimate the rates of recurrent imaging. The 75th percentile of distribution of 3rd quartiles of yearly CED is a reasonable benchmark for facilities to trigger optimisation. Investigating the underlying factors and addressing high recurrent rates can contribute to enhanced patient care.
Background/Objectives: T1 relaxation time has been shown to be valuable in detecting and characterizing tumors in various organs. This study aims to determine whether native T1 relaxation time can serve as a useful tool in distinguishing sarcomas from benign tumors. Methods: In this retrospective study, patients with histologically confirmed soft tissue sarcomas and benign tumors were included. Only patients who had not undergone prior treatment or surgery and whose magnetic resonance imaging (MRI) included native T1 mapping were considered. Images were acquired using both 1.5 T and 3 T MRI scanners. T1 histogram parameters were measured in regions of interest encompassing the entire tumor volume, as well as in healthy muscle tissue. Results: Out of 316 cases, 16 sarcoma cases and 9 benign tumor cases were eligible. The T1 values observed in sarcoma did not significantly differ from those in benign lesions in both 1.5 T and 3 T MRIs (p1.5T = 0.260 and p3T = 0.119). However, T1 values were found to be lower in healthy tissues compared to sarcoma at 3 T (p = 0.020), although this difference did not reach statistical significance at 1.5 T (p = 0.063). At both 1.5 T and 3 T, no significant difference between healthy muscle measured in sarcoma cases or benign tumor cases was observed (p1.5T = 0.472 and p3T = 0.226). Conclusions: T1 mapping has the potential to serve as a promising tool for differentiating sarcomas from benign tumors in baseline assessments. However, the standardization of imaging protocols and further improvements in T1 mapping techniques are necessary to fully realize its potential.
This study aims to provide radiation reference levels in orthopaedic surgery. A total of 753 procedures were collected within 1 y. Categories containing several similar procedures were created based on four criteria: same anatomical area, same level of complexity, only single procedures, and at least 10 cases per category. Exposure was defined in terms of air kerma-area product, fluoroscopy time, and air kerma at the patient entrance reference point. For common procedures, median effective doses to patient were calculated using the Monte Carlo Software PCXMC. Most irradiating procedure in this study i.e. intramedullary nailing of the proximal femur was equivalent to an air kerma at the patient entrance reference point of 37.1 mGy, which is similar to 50 times lower than the threshold for acute deterministic effects of radiation. Optimization remains a must to reduce the dose while maintaining the image quality and reducing the likelihood of stochastic effects.
The aim of this study is to propose diagnostic reference levels (DRLs) values for mammography in Switzerland. For the data collection, a survey was conducted among a sufficient number of centres, including five University hospitals, several cantonal hospitals, and large private clinics, covering all linguistic regions of Switzerland to be representative of the clinical practice. The data gathered contained the mean glandular dose (MGD), the compressed breast thickness (CBT), the mammography model and the examination parameters for each acquisition. The data collected was sorted into the following categories: 2D or digital breast tomosynthesis (DBT) examination, craniocaudal (CC) or mediolateral oblique (MLO) projection, and eight categories of CBT ranging from 20 mm to 100 mm in 10 mm intervals. A total of 24 762 acquisitions were gathered in 31 centres on 36 mammography units from six manufacturers. The analysis showed that the data reflects the practice in Switzerland. The results revealed that the MGD is larger for DBT than for 2D acquisitions for the same CBT. From 20-30 mm to 90-100 mm of CBT, the 75th percentile of the MGD values obtained increased from 0.81 mGy to 2.55 mGy for 2D CC acquisitions, from 0.83 mGy to 2.96 mGy for 2D MLO acquisitions, from 1.22 mGy to 3.66 mGy for DBT CC acquisitions and from 1.33 mGy to 4.04 mGy for DBT MLO acquisitions. The results of the survey allow us to propose Swiss DRLs for mammography according to the examination type (2D/DBT), projection (CC/MLO) and CBT. The proposed values are very satisfactory in comparison with other studies.
It is well known that foetuses are highly sensitive to ionising radiation and special attention to justification and optimisation of radiological procedures involving a pregnant patient is required. A task to review, validate and compare different approaches to managing the pregnant patient and to estimating the associated foetal doses arising from a diagnostic or interventional radiology (DIR) procedure was designed in the framework of EUR-ADOS working group 12.As a first step, a survey of radiation protection practice including dosimetry considerations among EURADOS members was performed using online questionnaire. Then, to evaluate the possible differences in the estimated foetal doses, a comparison of assessed dose values was made for three cases of pregnant patients that underwent different CT procedures.More than 120 professionals from 108 institutions and 17 countries that are involved in managing pregnant patients undergoing DIR procedures answered the questionnaire. Most of the respondents use national or hospital guidelines on the management of pregnant patients undergoing DIR procedures. However, the guidelines differ considerably among respondents. Comparison of foetal dose assessments performed by dosimetry experts showed the variety of methods used as well as large variability of estimated foetal doses in all three cases.Although European and International commission on radiation protection guidelines already exist, they are more than 20 years old and, in some aspects, they are obsolete. This paper shows that there is a need to revise and update these guidelines.
Clinical audit is an important quality improvement activity and has significant benefits for patients in terms of enhanced care, safety, experience and outcomes. Clinical audit in support of radiation protection is mandated within the European Council Basic Safety Standards Directive (BSSD), 2013/59/Euratom. The European Society of Radiology (ESR) has recognised clinical audit as an area of particular importance in the delivery of safe and effective health care. The ESR, alongside other European organisations and professional bodies, has developed a range of clinical audit-related initiatives to support European radiology departments in developing a clinical audit infrastructure and fulfilling their legal obligations. However, work by the European Commission, the ESR and other agencies has demonstrated a persisting variability in clinical audit uptake and implementation across Europe and a lack of awareness of the BSSD clinical audit requirements. In recognition of these findings, the European Commission supported the QuADRANT project, led by the ESR and in partnership with ESTRO (European Association of Radiotherapy and Oncology) and EANM (European Association of Nuclear Medicine). QuADRANT was a 30-month project which completed in Summer 2022, aiming to provide an overview of the status of European clinical audit and identifying barriers and challenges to clinical audit uptake and implementation. This paper summarises the current position of European radiological clinical audit and considers the barriers and challenges that exist. Reference is made to the QuADRANT project, and a range of potential solutions are suggested to enhance radiological clinical audit across Europe.
BACKGROUND:Patients can be exposed to high skin doses during complex interventional cardiology (IC) procedures.PURPOSE:To identify which clinical and technical parameters affect patient exposure and peak skin dose (PSD) and to establish dose reference levels (DRL) per clinical complexity level in IC procedures.MATERIAL AND METHODS:Validation and Estimation of Radiation skin Dose in Interventional Cardiology (VERIDIC) project analyzed prospectively collected patient data from eight European countries and 12 hospitals where percutaneous coronary intervention (PCI), chronic total occlusion PCI (CTO), and transcatheter aortic valve implantation (TAVI) procedures were performed. A total of 62 clinical complexity parameters and 31 technical parameters were collected, univariate regressions were performed to identify those parameters affecting patient exposure and define DRL accordingly.RESULTS:Patient exposure as well as clinical and technical parameters were collected for a total of 534 PCI, 219 CTO, and 209 TAVI. For PCI procedures, body mass index (BMI), number of stents ≥2, and total stent length >28 mm were the most prominent clinical parameters, which increased the PSD value. For CTO, these were total stent length >57 mm, BMI, and previous anterograde or retrograde technique that failed in the same session. For TAVI, these were male sex, BMI, and number of diseased vessels. DRL values for Kerma-area product (PKA), air kerma at patient entrance reference point (Ka,r), fluoroscopy time (FT), and PSD were stratified, respectively, for 14 clinical parameters in PCI, 10 in CTO, and four in TAVI.CONCLUSION:Prior knowledge of the key factors influencing the PSD will help optimize patient radiation protection in IC.
Osteoarthritis (OA) is a prevalent disease and the leading cause of pain, disability, and quality of life deterioration. Our study sought to evaluate the image quality and dose of cone-beam computed tomography arthrography (CBCT-A) and compare them to digital radiography (DR) for OA diagnoses. Overall, 32 cases of CBCT-A and DR with OA met the inclusion criteria and were prospectively analyzed. The Kellgren and Lawrence classification (KLC) stage, sclerosis, osteophytes, erosions, and mean joint width (MJW) were compared between CBCT-A and DR. Image quality was excellent in all CBCT-A cases, with excellent inter-observer agreement. OA under-classification was noticed with DR for MJW (p = 0.02), osteophyte detection (<0.0001), and KLC (p < 0.0001). The Hounsfield Unit (HU) values obtained for the cone-beam computed tomography CBCT did not correspond to the values for multi-detector computed tomography (MDCT), with a greater mean deviation obtained with the MDCT HU for Modeled Based Iterative Reconstruction 1st (MBIR1) than for the 2nd generation (MBIR2). CBCT-A has been found to be more reliable for OA diagnosis than DR as revealed by our results using a three-point rating scale for the qualitative image analysis, with higher quality and an acceptable dose. Moreover, the use of this imaging technique permits the preoperative assessment of extremities in an OA diagnosis, with the upright position and bone microarchitecture analysis being two other advantages of CBCT-A.
BACKGROUND:Optimizing patient exposure in interventional cardiology is key to avoid skin injuries.PURPOSE:To establish predictive models of peak skin dose (PSD) during percutaneous coronary intervention (PCI), chronic total occlusion percutaneous coronary intervention (CTO), and transcatheter aortic valve implantation (TAVI) procedures.MATERIAL AND METHODS:A total of 534 PCI, 219 CTO, and 209 TAVI were collected from 12 hospitals in eight European countries. Independent associations between PSD and clinical and technical dose determinants were examined for those procedures using multivariate statistical analysis. A priori and a posteriori predictive models were built using stepwise multiple linear regressions. A fourfold cross-validation was performed, and models' performance was evaluated using the root mean square error (RMSE), mean absolute percentage error (MAPE), coefficient of determination (R²), and linear correlation coefficient (r).RESULTS:Multivariate analysis proved technical parameters to overweight clinical complexity indices with PSD mainly affected by fluoroscopy time, tube voltage, tube current, distance to detector, and tube angulation for PCI. For CTO, these were body mass index, tube voltage, and fluoroscopy contribution. For TAVI, these parameters were sex, fluoroscopy time, tube voltage, and cine acquisitions. When benchmarking the predictive models, the correlation coefficients were r = 0.45 for the a priori model and r = 0.89 for the a posteriori model for PCI. These were 0.44 and 0.67, respectively, for the CTO a priori and a posteriori models, and 0.58 and 0.74, respectively, for the TAVI a priori and a posteriori models.CONCLUSION:A priori predictive models can help operators estimate the PSD before performing the intervention while a posteriori models are more accurate estimates and can be useful in the absence of skin dose mapping solutions.
Objectives Contact shielding (CS) of patients during X-ray studies has been used for decades to protect radiosensitive organs. This practice has not changed much despite increasing evidence that CS is not useful in many cases. The Gonad And Patient Shielding (GAPS) group—founded by representatives of the main European bodies involved in radiology—promoted this survey to assess the current practice of CS among European radiology departments and the attitude towards a non-shielding policy. Methods Over a four-month period (15 May–15th September 2021) European Society of Radiology and European Society of Paediatric Radiology radiologist members were invited to respond to a web-based questionnaire consisting of 59 questions. Results 225 centres from 35 countries responded to this survey. CS was routinely applied in at least one radiological modality in 49.2% of centres performing studies in adults, 57.5% of centres performing studies in children, and 47.8% of centres performing studies on pregnant women. CS was most frequently used in conventional radiography, where the most frequently shielded organs were the gonads, followed by thyroid, female breasts, and eye lens. 83.6% respondents would follow European recommendations on the use of CS when provided by the main European bodies involved in radiology. Conclusions This review shows that CS is still largely used across Europe. However, a non-shielding policy could be adopted in most departments if European professional societies provided recommendations. In this regard, a strong commitment by European and national professional societies to educate and inform practitioners, patients and carers is paramount. Clinical relevance statement According to this survey expectations of patients and carers, and skepticism among professionals about the limited benefits of CS are the most important obstacles to the application of a no-shielding policy. A strong commitment from European and national professional societies to inform practitioners, patients and carers is fundamental. Graphical Abstract
Purpose: Patient shielding during medical X-ray imaging has been increasingly criticized in the last years due to growing evidence that it often provides minimal benefit and may even compromise image quality. In Europe, and as also shown in a short assessment in Switzerland, the use of patient shielding is inhomogeneous. The aim of this study was to systematically review recent literature in order to assess benefits and appraise disadvantages related to the routine use of patient shielding. Methods: To evaluate benefits and disadvantages related to the application of patient shielding in radiological procedures, a systematic literature review was performed for CT, radiography, mammography and fluoroscopyguided medical X-ray imaging. In addition, reports from medical physics societies and authorities of different countries were considered in the evaluation. Results: The literature review revealed 479 papers and reports on the topic, from which 87 qualified for closer analysis. The review considered in- and out-of-plane patient shielding as well as shielding for pregnant and pediatric patients. Dose savings and other dose and non-dose related effects of patient shielding were considered in the evaluation. Conclusions: Although patient shielding has been used in radiological practice for many years, its use is no longer undisputed. The evaluation of the systematic literature review of recent studies and reports shows that dose savings are rather minimal while significant dose- and non-dose-related detrimental effects are present. Consequently, the routine usage of patient protection shielding in medical X-ray imaging can be safely discontinued for all modalities and patient groups.
EURADOS (European Radiation Dosimetry Group) Working Group 12 (WG12) SG1 activities are aimed at occupational radiation protection and individual monitoring in X-ray and nuclear medicine practices. In recent years, many studies have been carried out in these fields, especially for interventional radiology and cardiology workplaces (IC/IR). The complexity of the exposure conditions of the medical staff during interventional practices makes the radiation protection and monitoring of the exposed workers a challenging task. The scope of the present work is to review some of the main results obtained within WG12 activities about scattered field characterization and personal dosimetry that could be very useful in increasing the quality of radiation protection of the personnel, safety, and awareness of radiation risk. Two papers on Monte Carlo modelling of interventional theater and three papers on active personal dosimeters (APDs) for personnel monitoring were considered in the review. More specifically, Monte Carlo simulation was used as the main tool to characterize the levels of exposure of the medical staff, allowing to determine how beam energy and direction can have an impact on the doses received by the operators. Indeed, the simulations provided information about the exposure of the operator’s head, and the study concluded with the determination of an eye-lens protection factor when protection goggles and a ceiling shielding are used. Moreover, the review included the results of studies on active personal dosimeters, their use in IC/IR workplaces, and how they respond to calibration fields, with X-ray standard and pulsed beams. It was shown that APDs are insensitive to backscatter radiation, but some of them could not respond correctly to the very intense pulsed fields (as those next to the patient in interventional practices). The measurements during interventional procedures showed the potential capability of the employment of APDs in hospitals.
The use of patient contact-shielding has become a topic of intensive scientific debate. While it has been common practice during the last decades, some studies have questioned the efficiency of using such shielding while others have highlighted the inconsistencies in its application. The objective of this work is to review current recommendations and legislative documents on the use of out-of-field shielding in X-ray imaging, including those from national authorities and from international and national organisations and professional bodies. The review, performed within the framework of the activities of EURADOS Working Group 12, covers available recommendations on use of contact shielding in adult, pregnant and paediatric patients in general radiography, fluoroscopy, computed tomography, mammography and dental radiology. It includes a comprehensive search of 83 documents from 32 countries and 6 international organisations over the last 39 years. In general, using shielding is recommended only under two conditions: if it does not compromise the diagnostic task and the performance of the procedure and/or if it reassures the patient and comforters that they are appropriately protected against potentially harmful effects of radiation. There are very few specific regulatory requirements to use shielding in a particular imaging modality, although they may consider use of shielding either as part of good radiological practice or as requirements for availability of protective or ancillary tools, without further specification of their use. There is a wide variety of positions among documents that recommend out-offield shielding, those that do not recommend it and those that are not specific. Therefore, evidence-based consensus is still needed to ensure best and consistent practice.
Cone beam computed tomography (CBCT) has been available since the late 1990s for use in dentistry. European legislation requires optimisation of protection and the use of diagnostic reference levels (DRLs) as well as regular quality control (QC) of the imaging devices, which is well outlined in existing international recommendations. Nevertheless, the level of application is not known. Earlier studies have indicated that few European countries have established DRLs and that patient doses (exposure parameters) have not been properly optimised. The EURADOS Working Group 12-Dosimetry in Medical Imaging undertook a survey to identify existing practices in Member States. Questionnaires were developed to identify equipment types, clinical procedures performed, and exposure settings used. The surveys were circulated to 22 countries resulting in 28 responses from 13 countries. Variations were identified in the exposure factors and in the doses delivered to patients for similar clinical indicators. Results confirm that patient doses are still not properly optimised and DRLs are largely not established. There is a need to promote the importance of performing QC testing of dental CBCT equipment and to further optimise patient exposure by establishment and use of DRLs as a part of a continuous optimisation process.
Purpose: Online and offline software products can estimate the maximum skin dose (MSD) delivered to the patient during interventional cardiology procedures. The capabilities and accuracy of several skin dose mapping (SDM) software products were assessed on X-ray systems from the main manufacturers following a common protocol. Methods: Skin dose was measured on four X-ray systems following a protocol composed of nine fundamental irradiation set-ups and three set-ups simulating short, clinical procedures. Dosimeters/multimeters with semiconductor-based detectors, radiochromic films and thermoluminescent dosimeters were used. Results were compared with up to eight of 10 SDM products, depending on their compatibility. Results: The MSD estimates generally agreed with the measurements within ? 40% for fundamental irradiation set-ups and simulated procedures. Only three SDM products provided estimates within ? 40% for all tested configurations on at least one compatible X-ray system. No SDM product provided estimates within ? 40% for all combinations of configurations and compatible systems. The accuracy of the MSD estimate for lateral irradiations was variable and could be poor (up to 66% underestimation). Most SDM products produced maps which qualitatively represented the dimensions, the shape and the relative position of the MSD region. Some products, however, missed the MSD region when situated at the intersection of multiple fields, which is of radiation protection concern. Conclusions: It is very challenging to establish a common protocol for quality control (QC) and acceptance testing because not all information necessary for accurate MSD calculation is available or standardised in the radiation dose structured reports (RDSRs).
Purpose: In interventional cardiology, patients may be exposed to high doses to the skin resulting in skin burns following single or multiple procedures. Reviewing and analysing available software (online or offline) may help medical physicists assessing the maximum skin dose to the patient together with the dose distribution during (or after) these procedures. Method and results: Capabilities and accuracy of available software were analysed through an extensive bibliography search and contacts with both vendor and authors. Their markedly differed among developers. In total, 22 software were identified and reviewed according to their algorithms and their capabilities. Special attention was dedicated to their main features and limitations of interest for the intended clinical use. While the accuracy of the 12 software products validated with measurements on phantoms was acceptable (within +/- 25%), the agreement was poor for the two products validated on patients (within +/- 43% and +/- 76%, respectively). In addition, no software has been validated on angiographic units from all manufacturers, though several software developers claimed vendor-independent transportability. Only one software allows for multiple procedures dose calculation. Conclusion: Large differences among vendors made it clear that work remains to be done before an accurate and reliable skin dose mapping is available for all patients.
In interventional cardiology (IC), patients may be exposed to high doses to the skin resulting in tissue reactions (skin burns) following single or multiple procedures. As the number and complexity of IC procedures have been steadily growing, online and offline software has been developed to estimate the maximum skin dose (MSD) to the patient during (or after) IC procedures. However, the capabilities and accuracy of such skin dose calculation (SDC) software to estimate MSD and 2D dose distributions markedly differ among vendors. In addition, there is currently no protocols for testing such systems prior to release into clinical use or on regular basis. Acceptance and quality control (QC) testing protocols for the accuracy of SDC software in interventional cardiology were developed. The Acceptance protocol is composed of 13 fundamental irradiation set-ups and 3 clinical procedures, intended to represent more realistic conditions. The QC protocol is based upon the Acceptance protocol and is made of 8 fundamental irradiation setups. Measurements were performed following the Acceptance protocol on a GE Innova IGS 540, a Philips Allura Xper, a Siemens Artis Zee biplane and a Canon Infinix CF-i biplane. Calibrated solidstate dosimeters (multimeters), gafchromic films and thermoluminescent dosimeters were used for the measurements. Skin dose estimates were performed with 10 SDC software products in total: CareMonitor, Dose Tracking System, DOSE by Qaelum, DoseMap, em.dose, OpenSkin, Radiation Dose Monitor, DoseWatch Skin Dose Map (two versions) and SkinCare. At least 4 software products and up to 8 were used in combinations with a specific angiographic unit, depending on compatibility. The MSDs estimated by most SDC software products was within ±40% of the measurements during the fundamental irradiations and the clinical procedures. However, about half of the software products could not provide MSD estimates for lateral irradiations because a flat phantom was used. Among the remaining software products, accuracy of the MSD estimate for lateral irradiations was quite variable and could be very poor. Most SDC software produced maps representing acceptably the dimensions, the shape and the relative position of the MSD region. Some software, however, could miss the MSD region when situated at the thin intersection of multiple fields. The dimensions and shape of the MSD region were inaccurate for all SDC software on the Philips system because wedge filters were used, while most SDC software assumes square irradiation fields SDC software solutions can produce acceptable results and may include fine technical details of the procedure as calculation input; however, the determination of the patient body contour and position remains challenging. This can dramatically degrade the software accuracy particularly for lateral irradiations and irradiations that are not centred on the patient’s back.
Objective Estimations of radiation dose absorbed by the fetus from computed tomography (CT) in pregnant patients is mandatory, but currently available methods are not feasible in clinical routine. The aims of this study were to develop and validate a tool for assessment of fetal dose from CT of pregnant patients and to develop a user-friendly web interface for fast fetal dose calculations. Methods In the first study part, 750 Monte Carlo (MC) simulations were performed on phantoms representing pregnant patients at various gestational stages. The MC code simulating vendor-independent dose distributions was validated against CT dose index (CTDI) measurements performed on CT scanners of 2 vendors. The volume CTDI–normalized fetal dose values from MC simulations were used for developing the computational algorithm enabling fetal dose assessments from CT of various body regions at different exposure settings. In the institutional review board–approved second part, the algorithm was validated against patient-specific MC simulations performed on CT data of 29 pregnant patients (gestational ages 8–35 weeks) who underwent CT. Furthermore, the tool was compared with a commercially available software. A user-friendly web-based interface for fetal dose calculations was created. Results Weighted CTDI values obtained from MC simulations were in excellent agreement with measurements performed on the 2 CT systems (average error, 4%). The median fetal dose from abdominal CT in pregnant patients was 2.7 mGy, showing moderate correlation with maternal perimeter (r = 0.69). The algorithm provided accurate estimates of fetal doses (average error, 11%), being more accurate than the commercially available tool. The web-based interface (www.fetaldose.org) enabling vendor-independent calculations of fetal doses from CT requires the input of gestational age, volume CTDI, tube voltage, and scan region. Conclusions A tool for fetal dose assessments from CT of pregnant patients was developed and validated being freely available on a user-friendly web interface.