Two new antimicrobial metabolites, zopfiellamides A (1) and B (2) were isolated from fermentations of the facultative marine fungus Zopfiella latipes CBS 611.97. Their structures were elucidated by spectroscopic techniques, and they are pyrrolidinone derivatives.
The antifungal and cytostatic compound strobilurin M (1) is a new variant of the strobilurins produced by Mycena sp. 96097, a tropical basidiomycete. The same fungus was found to produce tetrachloropyrocatechol (3a) and tetrachloropyrocatechol methyl ether (3b), new natural products, which exhibit antifungal, antibacterial and cytotoxic activities.