Analyses of women dermatology literature authorship from 2018 to 2022 reveal a slight increase in total female authors, female first authors, and female senior authors with no substantial immediate impact of COVID-19 on current trends, encouraging future examination of long-term effects and ongoing promotion of systemic initiatives to support gender equity.
Background: Dermatologists are uniquely positioned within their highly innovative and fast-paced field to identify the limitations of existing technologies and devise original solutions to address them.
Background: Dermatologists continuously educate patients about the proper use of photoprotective products. Sunscreens formulated with zinc and titanium provide a physical barrier on the surface of the skin and demonstrate the most broad-spectrum protection against UVA and UVB light rays, but can leave a white cast on the skin. Tinted formulations offer a more cosmetically pleasing option, especially for individuals with Skin of Color (Fitzpatrick III-VI skin types). However, tinted sunscreens may be less affordable and more sparingly applied, thereby compromising photoprotection. Prices per ounce and percent differences in price between tinted sunscreens and their non-tinted counterparts were assessed on five popular skincare retailer websites (Amazon, Walmart, Ulta, Target, and Dermstore) in August 2022. A total of 156 products (78 pairs of tinted sunscreen and their non-tinted counterparts) were examined. Tinted sunscreens generally retailed for a higher price per ounce (median $17.64/ounce, range $4.59-$128.80/ounce) compared to non-tinted sunscreens (median $16.28/ounce, range $2.71-$67.73/ounce), and were found to cost an average of 23% more than non-tinted correlates. Average percentage differences in pricing between tinted and non-tinted sunscreens varied between retailers, ranging from 3.9% at Dermstore to 37.8% more for tinted products at Walmart. Higher prices for tinted sunscreens highlights a greater economic burden for individuals with darker skin who desire products matching their skin color. Dermatologists must be cognizant of cost discrepancies and financial barriers when recommending products. Dermatologists are encouraged to investigate products or work closely with product representatives in order to provide darker-skinned patients with affordable access to tinted sunscreens.
Background: Photoprotection in the form of sunscreen is indicated to decrease the deleterious effects of ultraviolet (UV) radiation, including skin damage and photocarcinogenesis. Cannabidiol (CBD), a natural occurring phytocannabinoid, has demonstrated anti-inflammatory and antioxidative properties in several studies, but limited research has explored the properties of CBD-containing sunscreen. To summarize current knowledge, the PubMed database was searched for peer-reviewed publications related to cannabidiol, UV, and anti-oxidant/anti-inflammatory keywords and Medical Subject Headings (MeSH) topic search terms. The full text of each publication was independently reviewed by two authors, and all non-English language and duplicate material was excluded. The content of 12 articles published between 2019-2021 was included and analyzed for study type, safety and efficacy of CBD, potential mechanisms of action, and any features of supporting evidence. Of the 12 analyzed articles, 10 discussed anti- oxidative properties, 6 discussed anti-inflammatory effects, 5 discussed cell-signaling perturbations, and 3 discussed barrier integrity as affected by CBD. A majority (7) of the articles included experimental studies on human cell lines, while the others included animal studies (2), human studies (1), and reviews (2). All articles discussed beneficial effects of topical CBD treatment, with an overarching theme of sun protection with application. Preliminary evidence suggests that CBD may independently confer a dose- dependent UV-protective effect for keratinocytes and melanocytes related to its antioxidant characteristics. CBD may be a promising addition to sunscreen, but further investigation is required to assess safety, tolerability, and efficacy.
Gliomas are highly aggressive primary brain tumors that extensively invadethe surrounding normal tissue prior to the onset of symptoms. They are clas-sified from low to high grade (I–IV) malignancy depending on specific histo-logical characteristics [24]. High-grade gliomas (most commonly glioblastomamultiforme, WHO grade IV) are distinguished by necrosis and are the mostcommon type of gliomas found in adults, as well as the most rapidly grow-ing and the most invasive. Patients with glioblastomas (GBM) have a 100%fatality rate and a median survival time of 10–12 months after diagnosis andtreatment, with very few patients surviving beyond three years [2]. This com-bination of high degree of invasiveness and the inability of current medicalimaging technology to capture the full extent of invasion creates an ideal sit-uation for the development of a mathematical model that can shed light onthe extent of invasion and the possibility of improving treatments.The present mathematical model characterizes glioma growth and inva-sion in terms of only two dominant parameters: net rates of diffusion/motility(