Journal of the European Academy of Dermatology and VenereologyVolume 16, Issue 3 p. 284-285 Widespread and unusual presentations of cutaneous larva migrans acquired in tropical sandy beach resorts G Yosipovitch, Corresponding Author G Yosipovitch National Skin Centre, 1 Mandalay Road, Singapore 308205.Corresponding author, National Skin Centre, 1 Mandalay Road, Singapore 308205, tel. +65 2534455; fax +65 3506682; E-mail: gil@nsc.gov.sg===Search for more papers by this authorM Widijanti Sugeng, M Widijanti Sugeng National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this authorCS Seow, CS Seow National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this authorCL Goh, CL Goh National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this author G Yosipovitch, Corresponding Author G Yosipovitch National Skin Centre, 1 Mandalay Road, Singapore 308205.Corresponding author, National Skin Centre, 1 Mandalay Road, Singapore 308205, tel. +65 2534455; fax +65 3506682; E-mail: gil@nsc.gov.sg===Search for more papers by this authorM Widijanti Sugeng, M Widijanti Sugeng National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this authorCS Seow, CS Seow National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this authorCL Goh, CL Goh National Skin Centre, 1 Mandalay Road, Singapore 308205.Search for more papers by this author First published: 27 June 2002 https://doi.org/10.1046/j.1468-3083.2002.00487_1.xCitations: 15Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume16, Issue3May 2002Pages 284-285 RelatedInformation

International Journal of DermatologyVolume 40, Issue 1 p. 6-11 Post herpetic neuralgia and the dermatologist Maria Widijanti Sugeng MBBS, Maria Widijanti Sugeng MBBS National Skin Centre, SingaporeSearch for more papers by this authorGil Yosipovitch MD, Gil Yosipovitch MD National Skin Centre, SingaporeSearch for more papers by this authorGoh Chee Leok MBBS, MRCP(UK), FRCP(Edin.), Goh Chee Leok MBBS, MRCP(UK), FRCP(Edin.) National Skin Centre, SingaporeSearch for more papers by this author Maria Widijanti Sugeng MBBS, Maria Widijanti Sugeng MBBS National Skin Centre, SingaporeSearch for more papers by this authorGil Yosipovitch MD, Gil Yosipovitch MD National Skin Centre, SingaporeSearch for more papers by this authorGoh Chee Leok MBBS, MRCP(UK), FRCP(Edin.), Goh Chee Leok MBBS, MRCP(UK), FRCP(Edin.) National Skin Centre, SingaporeSearch for more papers by this author First published: 21 December 2001 https://doi.org/10.1046/j.1365-4362.2001.00079.xCitations: 4 Correspondence, Gil Yosipovitch, md, National Skin Centre, 1 Mandalay Road, Singapore 308205. E-mail: [email protected]Drug namesacyclovir: Zoviraxamytriptyline: Elavilcapsaicin cream: Zostrix creamcarabamazepin: Tegretolfamciclovir: Famvirlidocaine: Lidodermlorazepam: Ativanvalaciclovir: Valtrexvalproate sodium: Depakene Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Citing Literature Volume40, Issue1January 2001Pages 6-11 RelatedInformation

BACKGROUNDTreatment modalities for keloids, which are commonly found in Asians, include intralesional corticosteroid injections and cryotherapy as well as a combination of these two modalities. Few studies have been performed in a controlled fashion to evaluate the efficacy of these treatments.OBJECTIVEA controlled study, to evaluate the combined effect of intralesional corticosteroid injection with cryotherapy vs. intralesional corticosteroid or cryotherapy alone.METHODSTen patients completed the study: eight patients had at least three keloids and two had two keloids. Patients were treated for at least three sessions 4 weeks apart. The outcome of the lesions was compared between the treatments regarding the thickness of the lesion using a caliper and photographic assessment, and the presence of itch and pain before and after treatment using a visual analogue scale.RESULTSIn terms of thickness, the keloids responded significantly better to combined cryotherapy and triamcinolone vs. triamcinolone alone or cryotherapy alone (P < 0.001). Pain intensity was significantly lowered with all treatment modalities; however, itch was lowered only with the combined treatment and intralesional corticosteroid alone. No significant side effects were noted with any of the treatments and no re-occurrence of keloids was noted with the combined therapy.CONCLUSIONCombined injection of intralesional steroids with cryotherapy appears to be superior to other current modalities.

BACKGROUND:Lichen simplex chronicus is a troublesome intractable itchy dermatosis, which may persist despite intensive topical treatments. Recently it has been demonstrated that topical aspirin solution with dichloromethane has a significant antipruritic effect in an experimentally induced itch.OBJECTIVE:The aim of this double-blind, crossover placebo trial was to evaluate the efficacy of this solution in the treatment of lichen simplex chronicus.METHODS:Twenty-nine patients with lichen simplex chronicus of at least 3 months' duration that did not respond to topical corticosteroids were randomized in a double-blind fashion to receive aspirin/dichloromethane solution in treatment period 1 for 2 weeks followed by placebo in treatment period 2 or placebo followed by aspirin in period 2 with a crossover design after a 2-week washout. The patients rated the pruritus intensity before and during therapy with a visual analog scale; a blinded investigator performed photographic assessment.RESULTS:A significant therapeutic response was achieved in 11 (46%) of the patients who completed the study compared with 3 patients (12%) receiving placebo. Overall, aspirin-treated patients experienced an average decrease in the visual analog scale of 2.18 +/- 2.86 versus 0.69 +/- 2.31 of those receiving placebo. The difference between the 2 treatments for week 2 was significant (P =.03).CONCLUSION:The study suggests that topical aspirin/dichloromethane might be a practical treatment for lichen simplex chronicus.

INTRODUCTION:Dermatomyositis is a condition well-known to medical physicians, especially rheumatologists and dermatologists. Classically, patients present with typical cutaneous features and proximal muscle weakness. Amyopathic dermatomyositis has been reported in recent literature where patients present with skin changes without muscle involvement.MATERIALS AND METHODS:We reviewed 28 patients diagnosed with dermatomyositis at the National Skin Centre over a 3-year period from 1996 to 1998 to assess the prevalence of this amyopathic variant in our local population and its association with malignancy.RESULTS:Out of the 28 patients, 13 (46.4%) had no clinical or laboratory evidence of myositis at presentation. Nine patients (32.1%) had clinical muscle weakness and 6 patients (21.4%) had laboratory evidence of myositis. Malignancies were detected in 12 patients (42.8%), half of which were nasopharyngeal carcinomas. There was no significant difference in the prevalence of malignancy between those with detectable muscle weakness (33.3%) and those without (47.4%). However, there was a significant higher prevalence of malignancy in those with clinical and laboratory evidence of myositis (66.6%) than those without (15.4%).CONCLUSION:We conclude that amyopathic dermatomyositis is a common presentation in our population and may have a lower risk of malignancy than the classical variant. Screening for malignancy, especially nasopharyngeal carcinoma, is recommended for all dermatomyositis patients.

BACKGROUND:Bacterial skin infections in children and adults are caused by different organisms with different antimicrobial susceptibility.METHODS:A comparative retrospective study was carried out on 233 adults and 53 children with bacterial skin infections. Skin swab cultures and sensitivity tests were performed using standard methods. Statistical analysis was performed using the Pearson chi-squared and Fisher tests. A P value of < 0.05 was considered to be significant.RESULTS:Primary and secondary skin infections occurred in equal proportions in children, whereas secondary skin infections were more common in adults (70.8%). Staphylococcus aureus was the main cause of skin infections, particularly in children (72.6%). S. aureus in children and adults was highly susceptible to cloxacillin, cephalexin, chloramphenicol, neomycin, cotrimoxazole, and clindamycin, moderately susceptible to erythromycin, and insensitive to tetracycline, ampicillin, and penicillin.CONCLUSIONS:It is important to monitor the trends of bacterial infections and their antibiotic susceptibility as this can assist medical practitioners in their choice of antimicrobial therapy. Such monitoring will also help to detect the emergence of resistant bacterial strains and caution us to take care in the use of certain drugs.

Cutaneous manifestations of dermatomyositis commonly include Gottron's papules, heliotrope rash, photosensitivity, poikiloderma and nailfold telangiectasia. Vesicles and bulla are rare. We report a patient with dermatomyositis who presented with blisters and oral ulcers. It is important to recognise this bullous variant in order to avoid a delay in diagnosis. Bullous dermatomyositis may also portend a poorer prognosis. Our patient was subsequently diagnosed to have undifferentiated nasopharyngeal carcinoma.