A chemo-enzymatic method is proposed for the preparation of ( S,S )-2,2′-(ethylenediamino)dibutan-1-ol based on the synthesis of racemic (±)- N -carbobenzoxy-2-amino-butan-1-ol and its enantioselective acylation in the presence of lipase at a key resolution step to release the optically active alcohol.

We showed a possibility of using 5-hydroxy-1-phenylimidazolidine-2-thione as an amidoalkylating agent in the reactions with 1-methyloxindole, 3-pyrazolone, and pyrazole derivatives to obtain a number of new unsymmetric bis-heterocyclic compounds with a direct C-C bond containing a combination of pharmacophoric groups of two classes of heterocycles.

Amidoalkylation of indole, oxindole, pyrazolone, and pyrazole derivatives using 5-hydroxy-1-phenylimidazolidin-2-one afforded a number of new unsymmetric bis-heterocyclic compounds with a direct C-C bond. The 3-(2-oxoimidazolidin-5-yl)indole derivatives were found to possess anti-inflammatory activity and relatively low cytotoxicity.

The review systematizes material by key types of reactions promoted by iron carbonyls. The reaction types are subdivided into several principal directions, focusing mainly on new examples where iron carbonyls are used in the synthetically valuable C-C bond formation processes.

The fluorenyl dendrimers 1,3,5-tris(2-fluorenyl)benzene and 1,3,5-tris[2-(9,9-dioctylfluorenyl)]benzene, which are model compounds for branched oligophenylenefluorenes, are prepared via the cyclocondensation of unsubstituted and dioctyl-substituted acetylfluorenes, respectively. Branched oligophenylenefluorenes are synthesized via the copolycondensation of phenyl-bis(pinacol diborate) with tribromoarylenes in the presence of the ferrocenyl complex of Pd via the Suzuki reaction A 3 + B 2 . For solutions of model compounds and oligophenylenefluorenes, absorption and fluorescence spectra are measured and interpreted. In the case of the branched oligomers, no aggregation of luminophore fragments occurs, an advantageous feature that distinguishes the branched oligomers from well-known linear luminescent polymers.

Different behaviors of α- and β-carbynes under conditions of high temperatures and pressures were studied.

The literature data concerning the effect of high pressures (9 GPa) and temperatures (1800°C) on polyadamantane is revised. A new diamond-like carbon is formed, whose structure is similar to that of natural skeletal diamond.

The structure of a new cubic form of diamond-like carbon, obtained by heating amorphous carbyne on the surface of materials with cubic crystal lattices, was investigated. This form was shown to have a well-like structure.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The influence of the structure of carbyne on the preparation of diamond was considered. Carbyne obtained by the dehydrohalogenation of polyvinylidene halides is a precursor of diamond and α-carbyne.

Highly disperse diamond (HDD) was obtained by heating amorphous carbyne in the presence of small amounts of HDD.

The transformation of carbyne into a new diamond-like form of carbon under normal pressure at a temperature of 360–400 °C was observed.