Die vorliegende Datenanalyse geht auf die Aspekte der Patientenzufriedenheit nach Botulinumtoxin-A- (BTX-A-)Behandlung, die Veränderung bestimmter Parameter wie Miktionsfrequenz und Vorlagenverbrauch sowie insbesondere auf die Anwendbarkeit des ICIQ-SF („International Consultation on Incontinence Questionnaire Short-Form“) und der UPS („Urgency Perception Scale“) bei Patientinnen mit überaktiver Blase (OAB) ein.

Die überaktive Blase („overactive bladder“, OAB) betrifft in Deutschland knapp 6,5 Mio. Menschen im Alter von 40 oder mehr Jahren. Die primäre Therapie besteht in der Verabreichung von Anticholinergika oder β3-Mimetika. Die Therapietreue bei Anticholinergika ist gering und wird mit 40 % nach 4 Monaten angegeben. Dies ist möglicherweise auf den großen Anteil von Nonrespondern zurückzuführen. Voraussetzung für das Wirken der genannten Arzneimittel ist das Vorhandensein von Detrusorüberaktivitäten (DO). DO werden aber nur in einem geringen Anteil mit der Standardurodynamik nachgewiesen. Mit der WiKa können im In-vitro-Versuch über einen Zeitraum von bis zu 72 h DO erfasst werden. Ziel ist es, zukünftig durch DO-Nachweis eine gezielte OAB-Therapie zu realisieren.

In Germany, overactive bladder (OAB) syndrome affects around 6.5 million people over the age of 40. The primary treatment consists of anticholinergics or beta-3-receptor agonists. After an anticholinergic treatment period of around 4 months, compliance is around 40%, which is probably due a larger proportion of nonresponders. One condition of an efficient medication treatment is the presence of detrusor overactivity (DO). However, the detection rate of DO during standard urodynamics is very low. The primary goal in the future is to target OAB treatment by detection of DO. Using the Wille Capsule (WiCa) in an in vitro model, DO could be detected over a time period of 72 h, which would ensure a higher compliance to the OAB treatment in a positive way.

The urodynamics is considered as a standard diagnostic test for urinary incontinence. For this test, transurethral catheter tip sensors are used to measure the pressure inside the bladder. The measurement takes about 25 minutes, and often it is not possible to monitor pathological changes of pressure during this period. Additionally, different psychological factors could affect the results of standard urodynamics. We have developed a new system for catheterless urodynamic measurement. The system consists of an implantable intravesical capsule that measures the pressure for a period of more than 72 hours. It needs no components outside the human body, so an outpatient treatment is possible, which allows measurements under conditions of the patient's daily routine.

The injection of air or water into the scrotum has been described only a few times so far in the literature. Injection of air into the penis and its consequences has not been described at all. Here, we present the case of a young man who, acting on his previously suppressed sexual fantasies, injected air into his penis and caused generalized subcutaneous emphysema.

Urodynamics is considered as a standard diagnostic test for urinary incontinence using catheter tip sensors to measure the bladder pressure. Standard urodynamic measurement takes about 30 minutes, thus it is often not possible to monitor pathological change of pressure during this short period of time. In addition, different psychosocial factors could affect the result of standard urodynamics. In this paper we describe a new system for catheterless urodynamic measurement. The system consists of an implantable intravesical capsule that measures the pressure over a period of up to 72 hours. The system needs no components outside of the human body, so an outpatient treatment is possible, which allows measurements under conditions of the patient's daily routine.