This paper reports on the design, development, and test of a multi-channel wireless micro-electrocorticography (µECoG) system. The system consists of a semi-implantable, ultra-compact recording unit and an external unit, interfaced through a 2.4 GHz radio frequency data telemetry link with 2 Mbps (partially used) data transfer rate. Encased in a 3D-printed 2.9 cm × 2.9 cm × 2.5 cm cubic package, the semi-implantable recording unit consists of a microelectrode array, a vertically-stacked PCB platform containing off-the-shelf components, and commercially-available small-size 3.7-V, 50 mAh lithium-ion batteries. Two versions of microelectrode array were developed for the recording unit: a rigid 4 × 2 microelectrode array, and a flexible 12 × 6 microelectrode array, 36 of which routed to bonding pads for actual recording. The external unit comprises a transceiver board, a data acquisition board, and a host computer, on which reconstruction of the received signals is performed. After development, assembly, and integration, the system was tested and validated in vivo on anesthetized rats. The system successfully recorded both spontaneous and evoked activities from the brain of the subject.

This paper reports on the design and development of a compact micro-electrocorticography (μECoG) system. The system is designed to record 8 channels of ECoG signals. Recorded neural data are sent off the system through a capacitive data telemetry link to the external world. The system has been prototyped using off-the-shelf electronic components and custom-designed electrodes, link, and package. For the verification of the function of the system, function of the building blocks was first individually tested, and then the cascade of the electrode array followed by the analog signal preconditioning block was tested in-vivo.