Background/Purpose: Addenbrooke's Cognitive Examination-Revised [1] is a highly sensitive and specific bedside test for the diagnosis of dementia. The aim of this study was to validate a Greek version of this simple, bedside instrument and to investigate its psychometric properties.Method: We translated and administered the Greek version of the ACE-R to 95 individuals comprising two groups: a dementia group (n = 35) and an age-matched and education-matched healthy control group (n = 60).Results: Our results suggest high internal consistency and very good sensitivity, specificity and negative predictive value, but only adequate positive predictive value for the ACE-R, with excellent diagnostic accuracy. In our sample, the ratio of verbal fluency plus language scores to orientation plus memory (VLOM) subscore failed to discriminate patients in the target dementia group.Conclusion: The present findings support the usefulness of the ACE-R as a brief dementia screening tool in clinical practice. Further neuropsychologic evaluation is required for the differential diagnosis of dementia.