INTRODUCTION:We aimed to evaluate the prevalence and relationship between childhood maltreatment (CMT) among patients with medication overuse headache (MOH) and to investigate whether CMT is associated with medication overuse in patients having headaches or with headaches that become chronic. Epidemiological studies report a relationship between childhood abuse and headache. There is growing knowledge about the evidence that childhood maltreatment leads to neurobiological sequel. Medication overuse is the most important problem for migraine to become chronic. But in the literature, there was no information about the role of childhood abuse in MOH and for migraine to become chronic.METHODS:A total of 116 patients with headache, aged from 15 to 65 years, were included in the study. Patients having chronic migraine (CM), MOH and episodic migraine (EM) were selected out of patients presented to the headache outpatient clinic. Types of headache were determined according to the revised International Headache Society (IHS) criteria published in 2004. The Childhood Trauma Questionnaire, Beck Depression Inventory and Beck Anxiety Inventory were performed. Presence of psychiatric co-morbidities was evaluated by a clinician using Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, the Fourth Edition.RESULTS:A total of 116 patients with headache were included in the study. Of patients, 64 had MOH, 25 had CM and 27 had EM. The prevalence of CMT, particularly emotional neglect (62%), physical neglect (44%) and emotional abuse (36.2%), was determined higher in all headache groups. There was no statistically significant difference in prevalence of childhood maltreatment between MOH, CM and EM groups. No statistically significant difference was detected between educational status, psychiatric co-morbidities and childhood trauma, except for physical neglect.CONCLUSION:Childhood maltreatment was observed in MOH as in other forms of migraine and headache. However, no significant difference was observed between the three groups of patients with headache.

Epilepsy affects not only the patient but also the patient's cohabiting relatives, to various degrees. This study investigated state and trait anxiety, depression, and social fear and avoidance levels in 48 adult patients with epilepsy and 48 family members, compared with 43 healthy control subjects, using the Beck Anxiety Inventory, the Beck Depression Inventory, the State-Trait Anxiety Inventory, and the Liebowitz Social Anxiety Scale. The results suggested that the patients and their first-degree relatives had higher levels of depression, state and trait anxiety, and avoidance compared with healthy subjects. The mothers of patients with epilepsy had the highest level of depression and anxiety.

Introduction: Major depressive disorder (MDD) is the most frequent comorbid psychiatric condition associated with obsessive-compulsive disorder (OCD).This study aimed to evaluate the prevalence of current depression in OCD, differences in socio-demographic and clinical characteristics, and obsessive-compulsive symptoms between OCD patients with and without depression.Additionally, factors associated with comorbid depression were investigated in our study.Methods: In total, 140 OCD patients, of which 63 were OCD patients with MDD (OCD+MDD, n=63) and 77 were OCD patients without depression (OCD-MDD, n=77) were included in the study.All patients were diagnosed with OCD using the Structured Clinical Interview for DSM-IV.The Yale-Brown Obsessive-Compulsive Scale, Beck Anxiety Scale, and Beck Depression Scale were administered to all patients.After the socio-demographic and clinical variables and scales were accomplished, the OCD patients divided into two groups as OCD with or without depression and we compared their mean scores of the variables and scales.Univariate analyses were followed by logistic regression.Results: There were no significant differences in age, gender, marital status, period without treatment, profession, medical and family history, and social support between the two groups.Anxiety, depression, and obsession and compulsion scores were significantly higher in the OCD+MDD group.The avoidance, insight, instability, and retardation scores of the OCD+MDD group were also significantly higher than those of the OCD-MDD group. Conclusion:Our study suggests that many factors are strongly associated with depression in OCD.Positive correlations between poor insight, severity of obsession and compulsion, and stressful life events during the last six months increased the risk of depression in OCD.Our study suggests that high level of avoidance, instability and retardation, history of suicidal attempt, and delayed treatment are other notable factors associated with the development of depression in OCD.

In this study, we investigated the effects of center-based childcare on the quality of life in healthy 2- to 4-year-old children. The study was conducted in the Başkent University School of Medicine Department of Pediatrics, and comprised 168 healthy 2- to 4-year-old children followed in the well-child outpatient clinic. After giving informed consent, the accompanying parent was asked to complete the parent proxy report of the Pediatric Quality of Life Inventory TM 4.0 and a sociodemographic information form. Among the children in the study group, 42.26% (n=71) were girls and 31.36 % (n=51) were attending childcare; 69% of the respondent parents were mothers (n=116). The mean total scale score of the study sample was 82.71 ±11.77. Total scale scores as well as psychosocial health, physical health, social functioning and emotional functioning subscale scores were significantly higher in children attending childcare. In particular, mothers whose children were attending center-based childcare perceived their children's quality of life as higher, regardless of their educational and employment status. Improving access to center-based childcare may help to improve the quality of life for young children in Turkey.

Objective: Attention Deficit/Hyperactivity Disorder (ADHD) is diagnosed using Diagnostic and Statistical Manual of Mental Disorders criteria, neuropsychological testing, examinations, and parent, teacher, and self-evaluation forms. Diagnosing of ADHD depends on clinical evaluation, others are auxilary methods. No biological, electrophysiological, or neuroimaging markers currently exist to diagnose ADHD. Many studies about the biological markers for diagnosing ADHD have been conducted. Olfactory and gustatory dysfunctions have not been well studied in ADHD for this purpose. For this reason this study aimed to evaluate both the olfactory and gustatory functions of children with ADHD. Methods: A total of 34 children with ADHD and a control group containing 31 children aged 6-15 years participated in the study. We used the Sniffin' Sticks odor tests and propylthiouracil (PROP) bitterness sensitivity test to examine odor and taste sensitivity, respectively. Results: We found no statistically significant differences between the ADHD and control groups in terms of odor sensitivity, odor discrimination, and odor identification. A statistically significant difference between groups was observed in PROP scores. Children in the ADHD group were less sensitive to bitterness than the control group. Conclusion: PROP bitterness test is in an advantageous state for being a marker in advanced years due to ease of use, independence of age and very short test period. As a result, in our study, it is concluded that PROP bitterness test may be a biological marker for ADHD diagnosis, however, further studies are needed.

INTRODUCTIONThe present study aimed to determine (a) the correlation between type and number of stressful life events and quality of life in patients with medication-overuse headache (MOH) and (b) whether stressful life events could be attributed to medication overuse and the conversion of headache to a chronic type.METHODSThe present study included 114 patients aged between 15 and 65 years who met the criteria for headache classification of International Headache Society (IHS). The patients were divided into three groups according to the revised 2004 IHS classification; MOH (n=64), chronic migraine (n=25) and episodic migraine (n=25). Detailed data on clinical and sociodemographic characteristics were recorded. Neurological and physical examinations were performed for differential diagnosis. The patients underwent structured clinical interviews for DSM-IV Inventory (SCID-I), Beck Anxiety Inventory, Beck Depression Inventory, Short Form-36 (SF-36) and Life Events List. Scores of these inventories were statistically compared.RESULTSComparing MOH group with episodic migraine group via SF-36, statistically significant decreases were observed in the subscales of physical role limitation (p=.024), pain (p=.0001), general health (p=.043) and social functioning (p=.004). There was a statistically significant correlation between the number of life events and the time the disease became chronic in the patient group with non-MOH chronic migraine (p=.027). Moreover, a statistically significant correlation was observed between stressful family life events and the body pain subscale of quality of life scale (p=.038).CONCLUSIONThe present study demonstrates that stressful life events impair quality of life in patients with MOH. It was also found that number of stressful life events could be attributed to the conversion of headache to a chronic type.

Anger plays a major role in psychodermatological diseases. Researchers have reported that anger and other psychological factors play a role in the etiology of chronic urticaria. This study aimed to examine symptoms of anger, anger-related behavioral patterns, thoughts associated with anger, situations that cause anger and experiences of interpersonal anger in patients with chronic spontaneous urticaria (CSU). The authors hypothesized that patients with CSU react to more situations with anger and experience more anger symptoms as compared to alopecia areata (AA) patients and healthy controls.

Background: Alopecia areata (AA) and psoriasis are common dermatological diseases which may be associated with psychosomatic origin. Close relationship with stressful life events has been shown both AA and psoriasis in previous studies. Dermatologic diseases which are thought to be psychosomatic origin are not examined about childhood traumas except AA. In the literature there is no study that investigates both stressful life events with childhood trauma in healthy indiviudals and dermatological diseases with psychosomatic origin such as AA and psoriasis.

Journal of Child and Adolescent PsychopharmacologyVol. 24, No. 4 Letters to the EditorRisperidone Treatment in a Case of Tourette Syndrome with Factor V Leiden Heterozygous MutationBurcu Akın Sarı, Nilgün Taşkıntuna, and Özhan YalçınBurcu Akın SarıPsychiatry Department, Başkent University Medical Faculty, Ankara, Turkey.Search for more papers by this author, Nilgün TaşkıntunaPsychiatry Department, Başkent University Medical Faculty, Ankara, Turkey.Search for more papers by this author, and Özhan YalçınChild and Adolescent Psychiatry Clinic, Bakirkoy Mental Health and Neurology Research Hospital, İstanbul, Turkey.Search for more papers by this authorPublished Online:19 May 2014https://doi.org/10.1089/cap.2013.0125AboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View article"Risperidone Treatment in a Case of Tourette Syndrome with Factor V Leiden Heterozygous Mutation." Journal of Child and Adolescent Psychopharmacology, 24(4), pp. 235–236FiguresReferencesRelatedDetailsCited byUpdate on the Pharmacological Treatment of Tics with Dopamine-Modulating Agents2 March 2018 | ACS Chemical Neuroscience, Vol. 9, No. 4 Volume 24Issue 4May 2014 InformationCopyright 2014, Mary Ann Liebert, Inc.To cite this article:Burcu Akın Sarı, Nilgün Taşkıntuna, and Özhan Yalçın.Risperidone Treatment in a Case of Tourette Syndrome with Factor V Leiden Heterozygous Mutation.Journal of Child and Adolescent Psychopharmacology.May 2014.235-236.http://doi.org/10.1089/cap.2013.0125Published in Volume: 24 Issue 4: May 19, 2014Online Ahead of Print:May 9, 2014PDF download

The aim of the study is to investigate the impact of psychiatric disorders with cardiac syndrome X (CSX) on the patients' quality of life, as well as the efficacy of psychiatric support. Fifty-six CSX and fifty-three Coronary Heart Disease patients were included in the study after coronary angiography. Patients were evaluated right after the angiography and 3 months thereafter. The socio-demographic characteristics, comorbid disorders, Beck Anxiety (BAI), Depression (BDI) Inventory, and Health Related Quality of Life (SF-36) were compared between groups. The most common mental disorders was depression which account for 41%, the next were anxiety disorders (64%, n = 36) and somatoform (24%, n = 14). Initially, BAI, BDI in the CSX group were significantly higher when compared to the control group. There was significant difference in all subgroups of SF-36 at the end of the second evaluation versus the first evaluation in the CSX patients. The present study revealed that patients with CSX have higher prevalence of psychiatric comorbidities and lower quality of life. Psychiatric approaches are benefit for CSX patients to improvement their quality of life.

OBJECTIVE:Delirium is frequently observed, but generally under recognized in elderly hospitalized patients. The aims of this study were to determine the prevalence of delirium in elderly patients hospitalized at a university hospital, and to determine the recognition rate by hospital staff during hospitalization.METHODS:The study included 108 consecutive patients aged ≥ 65 years that were hospitalized in the medical and surgical inpatient departments at Başkent University Hospital, Ankara, Turkey. All the patients were evaluated using the Mini Mental State Examination (MMSE) upon admission and Confusion Assessment Method (CAM) on a daily basis during hospitalization. Written documents and consultation requests from psychiatry and/or neurology departments were reviewed for recognition of delirium by hospital staff.RESULTS:Among the 108 patients in the study, delirium was noted in 18 (16.7%) during their hospital stay. Consultation from psychiatry or neurology departments was requested for 5 of the 18 patients, only 1 with a delirium diagnosis, indicating that 17 of the cases (94.4%) were not recognized by their primary physicians.CONCLUSIONS:The delirium non-recognition rate in elderly hospitalized patients was very high. We think that hospital staff must be trained to recognize the symptoms of delirium and identify high-risk patients.

Objective: The aim of this study was the management of emotional problems associated with chronic renal disease by using group psychotherapy in hemodialysis patients. Methods: 5 age-and education-matched subjects with emotional problems associated with their disease were included in the study. Group therapy has been conducted as "transactional group image therapy", for 1.5 hours, once a week, for a total of 11 sessions. Results: It was observed that the patients in the group therapy were going through either one or more stages of "denial, anger, bargaining, depression, acceptance". The stages were taken into consideration and the patients examined their own feelings and were able to talk about their disease. It was observed that the patients started to be able to cope with difficulties faced in daily life due to the disease, and that the compliance with treatment and their quality of life increased. As a result, it can be concluded that group psychotherapy was effective for patients with chronic renal disease in solving their emotional problems. Conclusion: It should be considered that enabling the widespread use of group therapy and conducting the therapy process with a longer duration would help these patients to cope with their disease easier. We assume that a structured scale would be a helpful tool in future studies on the effectiveness of group psychotherapy. (Archives xx Neuropsychiatry 2012;49: 63-7)