Gastric cancer is a major cause of cancer-related mortality, and reliable postoperative risk prediction is essential in critically ill patients. The C-reactive protein–albumin–lymphocyte (CALLY) index reflects inflammatory and nutritional status, while lactate indicates metabolic stress and tissue hypoperfusion. This study aimed to develop a lactate-based CALLY (CALLY-I) score and evaluate its prognostic value in postoperative gastric cancer patients admitted to the intensive care unit (ICU). This retrospective study included 186 patients who underwent gastric cancer surgery and required postoperative ICU care between January 2022 and January 2025. Demographic characteristics, laboratory parameters, APACHE II and SAPS II scores, and derived indices (CALLY and CALLY-I) were analyzed. Predictors of 30- and 90-day mortality were assessed using Receiver Operating Characteristic (ROC) analyses, and significant variables were included in multivariate logistic regression. The 30-day and 90-day mortality rates were 18.2

Objectives: The aim of this study is to investigate the relationship between the lactate/albumin ratio (LAR) and 28-day mortality in gastric cancer patients undergoing monitoring in a postoperative intensive care unit due to reasons such as haemodynamic instability, need for vasopressor support, or intraoperative bleeding. Methods: This retrospective study included patients followed up at the tertiary surgical intensive care unit of Kastamonu University Faculty of Medicine between January 2020 and October 2025 who were diagnosed with histologically confirmed gastric adenocarcinoma and underwent total open surgery or subtotal gastrectomy + D2 lymphadenectomy. The patients were categorized into two groups: non-survivors within 28 days (n: 45) and survivors within 28 days (n: 139). Results: A total of 184 critically ill patients (110 males, 74 females) who underwent gastric adenocarcinoma surgery and were followed up in the surgical intensive care unit were included in this study. The mean age of the patients was 72.2 ± 11.3 years. Of these patients, 139 (75.5%) were survivors, and 45 (24.5%) were non-survivors. Albumin, the C-reactive protein (CRP)/albumin ratio, lactate, and the lactate/albumin ratio were associated with 28-day mortality. Receiver operating characteristic (ROC) analysis showed that the LAR (area under the curve (AUC): 0.839) was superior to the serum albumin (AUC: 0.736) and lactate levels (AUC: 0.796) for predicting 28-day mortality. The optimal cut-off value of the LAR was 0.82, and an LAR of ≥ 0.82 was shown to be a significant and independent prognostic factor for 28-day mortality in patients with stomach cancer in a critical postoperative condition (odds ratio (OR): 4.78, confidence interval (CI): 1.09-21.08, p = 0.0386). Conclusions: The lactate/albumin ratio is a prognostic parameter for 28-day mortality in critically ill postoperative gastric cancer patients. The optimal cut-off value for the lactate/albumin ratio is 0.82.

Background: Hip fracture surgery patients admitted to the intensive care unit (ICU) have high postoperative mortality, and early risk stratification remains challenging. This study aimed to evaluate the predictive value of the C-reactive protein/albumin ratio (CAR) for 30-day and 90-day mortality in hip fracture surgery patients admitted to the ICU. Methods: This retrospective cohort study included 134 adult patients who underwent surgery for hip fracture and were admitted to the ICU between June 2021 and June 2023. Demographic characteristics, comorbidities, APACHE II and SAPS II scores, and laboratory parameters measured within the first 24 h of ICU admission were recorded. CAR was calculated by dividing CRP (mg/L) by albumin (g/dL). The primary outcomes were 30-day and 90-day mortality. Cox proportional hazards regression analysis was performed to identify independent predictors of mortality, and receiver operating characteristic (ROC) curve analysis was used to assess the discriminative ability of CAR. Results: The 30-day and 90-day mortality rates were 10.4% and 22.4%, respectively. CAR and serum albumin levels were significantly associated with both 30-day and 90-day mortality (p < 0.01), whereas CRP alone was not. In ROC analysis, CAR demonstrated excellent predictive performance for 30-day mortality (AUC: 0.991; 95% CI: 0.975–1.000; cutoff: 38.46; sensitivity: 92.9%; specificity: 92.5%) and good performance for 90-day mortality (AUC: 0.847; 95% CI: 0.776–0.918; cutoff: 25.43). Cox regression analysis identified CAR as an independent predictor of both 30-day (Exp(B) = 1.048, p < 0.001) and 90-day mortality (Exp(B) = 1.025, p = 0.002). Conclusions: The CRP/albumin ratio is a strong and independent predictor of short- and mid-term mortality in hip fracture surgery patients admitted to the ICU. Due to its simplicity and rapid availability, CAR may serve as a practical adjunctive biomarker for early risk stratification in this high-risk population.

Elderly patients with multiple comorbidities present significant anesthetic challenges during hip fracture surgery. In patients with limited cardiopulmonary reserve, both general and neuraxial anesthesia may be associated with substantial perioperative risk. This report describes the use of a combined regional anesthesia approach as an alternative strategy to achieve surgical anesthesia in a high-risk geriatric patient. An 82-year-old woman with severe cardiopulmonary comorbidities, including active pneumonia, reduced ejection fraction, pulmonary hypertension, dementia, and a potentially difficult airway, was scheduled for femoral neck fracture surgery. Following individualized multidisciplinary assessment of the patient’s respiratory, airway, and hemodynamic risks, an ultrasound-guided peripheral regional anesthetic strategy was selected. A combination of ultrasound-guided pericapsular nerve group (PENG), transmuscular quadratus lumborum (QLB III), and lateral femoral cutaneous nerve (LFCN) blocks was performed in the intensive care unit. Dexmedetomidine was continued without a loading dose, providing cooperative light sedation with a Richmond Agitation–Sedation Scale score between − 1 and 0. Surgery was performed in the lateral decubitus position and completed uneventfully. Hemodynamic stability and adequate oxygenation were maintained throughout the procedure, with no requirement for additional sedative or analgesic agents. Postoperative Faces Pain Scale scores were 0 at rest and 1 during movement, increasing to 4 at 12 h, when intravenous tramadol was administered. No anesthetic- or surgery-related complications were observed. The patient was transferred to the ward on postoperative day two. This case suggests that a carefully selected combination of regional anesthesia techniques may provide surgical anesthesia in selected high-risk geriatric patients when patient-specific considerations make general or neuraxial anesthesia less desirable. This individualized approach requires appropriate expertise, careful patient selection, and a clearly defined rescue plan.

Abstract Background The Parkland Grading Scale (PGS) is a practical intraoperative grading system used to assess operative difficulty during laparoscopic cholecystectomy. This study aimed to investigate the relationship between PGS scores and preoperative inflammatory indices and to evaluate whether these indices were associated with operative severity and intraoperative complexity. Methods This retrospective cross-sectional study included 1054 patients who underwent elective laparoscopic cholecystectomy for gallstone disease between January 2018 and January 2025. Demographic characteristics, laboratory parameters, inflammatory indices, operative duration, conversion rates, and PGS scores were analyzed. Univariate and multivariate logistic regression analyses were performed to identify variables independently associated with higher PGS severity. Receiver operating characteristic (ROC) curve analysis was used to determine diagnostic performance. Results According to the PGS classification, 451 patients were classified as PGS 1, 146 as PGS 2, 213 as PGS 3, 164 as PGS 4, and 80 as PGS 5. Operative duration and conversion from laparoscopic to open cholecystectomy increased significantly with increasing PGS scores ( p < 0.001). In multivariate logistic regression analysis, type 2 diabetes mellitus (T2DM), CRP/albumin ratio (CAR), neutrophil/lymphocyte ratio (NLR), and inflammatory burden index (IBI) were identified as independent predictors of higher PGS scores (all p < 0.001). ROC analysis demonstrated that IBI had the highest discriminatory performance (AUC: 0.792), followed by NLR (AUC: 0.766) and CAR (AUC: 0.764). Conclusions Preoperative inflammatory indices, particularly IBI, NLR, and CAR, were significantly associated with higher PGS scores and increased operative difficulty in laparoscopic cholecystectomy. These markers may help identify patients with increased operative complexity and improve preoperative surgical planning.

Background/Objectives: Our study aimed to identify risk factors for the development of ARDS (acute respiratory distress syndrome) in patients with sepsis resulting from peptic ulcer perforation. Methods: Between January 2018 and December 2025, patients aged 18 years and older who underwent open surgery for peptic ulcer perforation and were diagnosed with sepsis due to intra-abdominal infection related to peptic ulcer perforation during postoperative follow-up or hospitalization were included in the study. Daily ARDS screening was performed within 7 days of sepsis diagnosis. Patients were divided into groups with and without ARDS. Laboratory values were recorded within the first 24 h after sepsis diagnosis, and APACHE II score, SOFA score, NEWS, and SAPS II were calculated based on these values and the patient's clinical condition. Results: The SOFA score showed the highest discriminative ability, with an AUC of 0.710 (95% CI: 0.619-0.794) at a cutoff of 9.0, representing 54.2% sensitivity and 83.1% specificity. Albumin level showed an AUC of 0.654 (95% CI: 0.560-0.748) at a cutoff of 2.40 g/dL; its specificity was high (85.1%), but its sensitivity was relatively low (41.7%). CAR showed moderate predictive performance with an AUC of 0.627 (95% CI: 0.522-0.730) at a cutoff of 61.11, representing 60.4% sensitivity and 72.1% specificity. The combined model demonstrated the best predictive performance with an AUC of 0.727 (95% CI: 0.635-0.820), 70.8% sensitivity, and 72.7% specificity. Conclusions: SOFA score demonstrated the best overall clinical applicability for early ARDS risk stratification, while both SOFA score and APACHE II score showed independent associations with ARDS in separate multivariable models.

Sepsis is a life-threatening clinical syndrome associated with high morbidity and mortality in patients admitted to intensive care units. Early prediction of mortality risk is essential for timely interventions and optimal use of critical care resources. Although various prognostic scoring systems are available, many are complex or not easily applicable in daily clinical practice. Therefore, simple and reliable tools for early risk stratification are needed. The aim of this study was to evaluate the prognostic performance of the A-VIVO score in predicting early mortality in patients with sepsis. This retrospective, single-center observational study reviewed electronic medical records of adult patients diagnosed with sepsis according to the Sepsis-3 criteria and admitted to the intensive care unit between January 2020 and January 2025. Patients aged 18 years or older who were monitored for at least 48 h were included. Patients with missing data or unavailable mortality outcomes were excluded. Patients were classified as survivors or non-survivors based on 30-day mortality. The A-VIVO score was calculated using eight clinical and laboratory parameters, each scored from 0 to 2 points. A total of 683 patients were included. Of these, 400 patients (58.6

Aims: In recent years, the rate of admission to intensive care in the elderly population has been increasing. We aimed to investigate the relationship between the serum creatinine/alanine transaminase ratio (sCr/ALT), which is thought to be a simpler method for predicting mortality in the elderly patient group instead of intensive care scoring systems that are difficult to calculate, and mortality. Methods: Medical records of patients treated in the intensive care unit due to acute ischemic stroke between January 2017 and October 2021 were evaluated. The study included 189 patients over the age of 85 who were diagnosed with cerebrovascular disease, had no known liver or kidney disease, and had a creatinine value of <1.5 mg/dl. APACHE II, SAPS II, and NIHSS scores calculated during admission to the intensive care unit were calculated from system data and patient records. Demographic data, additional diseases, hospital stay, laboratory values, sCr/ALT ratios and 28-day mortality status of the patients were recorded. Results: In a total of 189 patients, 66 male and 123 female, included in the study, mortality occurred at a rate of 65.1% (n: 123) in the first 28 days. The presence of coronary artery disease (p=0.044) was significantly higher in mortal cases. There were statistically significant differences in APACHE II score (p<0.001), SAPS II (p<0.001), AST (p=0.008), creatinine (p<0.001), sCr/ALT ratio (p<0.001), neutrophil/lymphocyte ratio (p=0.049), ferritin (p=0.003) and CRP (p=0.006) in mortal cases and non-mortals. In mortal cases, NIHSS severe (p<0.001) percentage was significantly higher than in other patients. ALT (p<0.001), lymphocyte (p=0.009) and albumin (p<0.001) values were statistically significantly lower in mortal cases than in non-mortals. When we evaluated the 28-day mortality prediction performances of the variables, the sCr/ALT ratio was found to have 85.4% sensitivity and 84.8% specificity, the albumin value had 85.4% sensitivity and 60.6% specificity, and the APACHE II score had 61.8% sensitivity and 90.9% specificity . Conclusion: NIHSS, APACHI II and SAPS II are used as mortality and disease severity indicators in elderly intensive care patients with acute ischemic stroke. When compared with these scores, the sCr/ALT value is a valuable indicator in predicting mortality. We found that the sCr/ALT ratio, which is easily worked on and calculated in many centers, can better predict mortality in elderly patients with ischemic stroke.

Knee and hip arthroplasty are common orthopedic procedures that are frequently associated with moderate to severe postoperative pain. Regional anesthesia techniques play a crucial role in multimodal analgesia strategies for managing postoperative pain. The suprainguinal fascia iliaca (SIFI) block is an effective regional anesthesia technique frequently used for postoperative analgesia in lower extremity surgeries, including knee and hip arthroplasty. These techniques can be safely applied either as a single-shot injection or via continuous catheter insertion. In this case report, we describe our experience with the use of continuous SIFI block for postoperative analgesia in knee and hip arthroplasty.

A distal femur fracture is an orthopedic condition that can be seen in all age groups and causes severe pain both preoperatively and postoperatively. Poorly managed pain can lead to hemodynamic changes, the need for additional analgesic drugs containing opioids, increased hospital stay, delayed mobilization, and patient dissatisfaction. Regional anesthesia techniques can be used for preoperative and postoperative analgesia. Suprainguinal fascia iliaca block and pericapsular nerve group block are applications included in regional techniques that preserve motor functions of the thigh. We also share our experience of suprainguinal fascia iliaca block and pericapsular nerve group block catheter application that we applied to a patient who underwent tenolysis surgery due to a distal femur fracture and adhesion in the quadriceps muscle group.

Background We aimed to investigate the correlation between the inferior vena cava collability index(IVC-CI) used in the evaluation of fluid volume and the Nutrition Risk Index(NRI), Prognostic Nutrition Index(PNI), Geriatric Nutrition Risk Index(GNRI) and Controlling Nutritional Status Scoring(CONUT) used in the evaluation of malnutrition. MethodsThis study is a prospective observational study. Demographic data, laboratory data, Body Max Indexes(BMI), NRI, PNI, GNRI and CONUT in the first 24 hours of admission to the intensive care unit of 96 critically ill patients admitted to the tertiary intensive care unit with assisted invasive mechanical ventilator support and IVC-CI values were recorded. Patients with an IVC-CI >45% were evaluated as hypovolemia. Of the patients, 61 (63.5%) patients with an IVC-CI value of 45%≥ were group 1, and 35 (36.5%) patients with an IVC-CI value of >45% were determined as group 2. Correlation between the IVC-CI and malnutrition scores was investigated between the groups. Results As a result of the statistical analysis; there was a statistically significant difference between the two groups in terms of BMI, NRI, PNI, GNRI and CONUT (p<0.001). According to the correlation analysis results, NRI (rs=-0.716, p<0.001), PNI (rs=-0.743, p<0.001), GNRI (rs=-0.723, p<0.001), CONUT (rs=0.741, p<0.001) were significantly correlated with the IVC-CI.ConclusionsThis study shows that there is a correlation between the IVC-CI used in the evaluation of fluid volume and malnutrition.

Background This study by aiming to investigate the relationship of serum creatinine/alanine transaminase ratio(sCr/Alt) with mortality of patients aged 85 and over treated for acute ischemic stroke Methods Medical records of patients aged 85 and over treated for acute ischemic stroke between January-2017 and October-2021 were evaluated. A total of 189 patients over the age of 85 with a diagnosis of cerebrovascular disease were included in the study. Results When we evaluated the 28-day mortality prediction performance of the variables, ALT(p < 0.001), serum creatinine(p < 0.001), serum creatinine/alanine transaminase(p < 0.001) were significantly higher in the mortal cases than in the other patients. We evaluated the 28-day mortality prediction performances of the variables, the sCr/Alt ratio was found to have 85.4% sensitivity and 84.8% specificity. Conclusion sCr/Alt value is a more valuable marker compared to NIHSS, APACHE II and SAPS II values which are mortality markers in advanced elderly patients with acute ischemic stroke in intensive care.

Ultrasonography (USG) is a non-invasive, portable, bedside, reproducible, radiation-free, inexpensive, and easily accessible imaging method. It provides morphological and functional information. It allows for diagnosis, monitoring, and guiding treatment. The usage areas of USG in the ICU are broad. In interventional procedures (thoracentesis, vascular interventions, percutaneous tracheostomy), evaluation of lung pathologies (pneumothorax, pleural effusion, pulmonary edema, consolidation, A-line, B line), diaphragm evaluation, abdominal imaging (trauma, kidney, liver), diagnosis and follow-up of deep vein thrombosis and the assessment and follow-up of fluid resuscitation (IVCI) and neuromonitoring. USG-guided neuromonitoring can detect stenosis or occlusion of intracranial arteries, monitor the development of patients with vasospasm after subarachnoid hemorrhage, detect cerebral embolism, evaluate the cerebral collateral system, and determine brain death. It can also indirectly calculate intracranial pressure (ICP) and cerebral perfusion under USG guidance.

Background/Purpose: The aim of this study is to association the Prognostic Nutrition Index(PNI) and Geriatric Nutrition Risk Index(GNRI) with 28-day mortality in critically very elderly patients and compare these indexes with APACHE II and SAPS II scores. Methods: This study is a observational and retrospective study. A total of 189 patients aged 85 years and older who were followed up in the intensive care unit between 2017 and 2021 were included in the study. Demographic data of the patients included in the study, length of stay in the intensive care unit, comorbidities, laboratory data of hospitalization in the intensive care unit, neutrophil/lymphocyte ratios, thrombocyte/lymphocyte ratios, APACHE II, SAPS II, PNI and GNRI index values of intensive care admissions were recorded. Results: In the statistical analysis performed for PNI and GNRI between Survival and Non- survival groups, a statistically significant difference was found between the groups (p=0.022 for PNI, p=0.010 for GNRI). The optimal threshold values of PNI and GNRI were 33.8 and 92.6, respectively. Sensitivity and specificity were 56.1% and 56.9% for PNI, 60.6% and 60.2% for the GNRI. Conclusion: The prognostic nutrition index and geriatric nutrition risk index are associated with 28-day mortality and malnutrition in very elderly patients treated in the intensive care unit. However, these scorings are not as sensitive and specific as APACHE II and SAPS II scores in predicting 28-day mortality.

Background and Objectives: Cardiopulmonary bypass (CPB) is an extracorporeal circuit that provides surgical access to an immobile and bloodless area, allowing for technical and procedural advances in cardiothoracic surgery. CBP can alter the integrity of the blood–brain barrier and cause changes in intracranial pressure (ICP) postoperatively. Optical nerve sheath diameter (ONSD) measurement is among the alternative non-invasive methods for ICP monitoring. In this study, we aimed to evaluate the optic nerve sheath diameter measurements under the guidance of ultrasonography for ICP changes during the extracorporeal circulation process. Materials and Methods: The study population included 21 patients over 18 years of age who required extracorporeal circulation. Demographic data of the patients, such as age, gender, comorbidity, American Society of Anesthesiologists (ASA) classification and reason for operation (coronary artery disease or mitral or aortic valve disease) were recorded. The ONSD was measured and evaluated before the extracorporeal circulation (first time) and at the 30th minute (second time), 60th minute (third time) and 90th minute (fourth time) of the extracorporeal circulation. Non-invasive ICP (ICP ONSD) values were calculated based on the ONSD values found. Results: The mean ONSD values measured before the extracorporeal circulation of the patients were found to be 4.13 mm (3.8–4.6) for the right eye and 4.36 mm (4.1–4.7) for the left eye. Calculated nICPONSD values of 11.0 mm Hg (1.0–21.0) for the right eye and 10.89 mm Hg (1.0–21.0) for the left eye were found. It was observed that there was a significant increase in the ONSD and nlCPONSD values recorded during the extracorporeal circulation of all patients compared to the baseline values (p < 0.005). Conclusions: During extracorporeal circulation, ultrasound-guided ONSD measurement is an easy, inexpensive and low-complication method that can be performed at the bedside during the operation to monitor ICP changes.

Background The coronavirus disease 2019 (COVID-19) pandemic has resulted in high mortality among patients in critical intensive care units. Hence, identifying mortality markers in the follow-up and treatment of these patients is essential. This study aimed to evaluate the relationships between mortality rates in patients with COVID-19 and the neutrophil/lymphocyte ratio (NLR), derived NLR (dNLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), systemic inflammation response index (SII), and systemic inflammatory response index (SIRI). Methodology In this study, we assessed 466 critically ill patients diagnosed with COVID-19 in the adult intensive care unit of Kastamonu Training and Research Hospital. Age, gender, and comorbidities were recorded at the time of admission along with NLR, dNLR, MLR, PLR, SII, and SIRI values from hemogram data. Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and mortality rates over 28 days were recorded. Patients were divided into survival (n = 128) and non-survival (n = 338) groups according to 28-day mortality. Results A statistically significant difference was found between leukocyte, neutrophil, dNLR, APACHE II, and SIRI parameters between the surviving and non-surviving groups. A logistic regression analysis of independent variables of 28-day mortality identified significant associations between dNLR (p = 0.002) and APACHE II score (p < 0.001) and 28-day mortality. Conclusions Inflammatory biomarkers and APACHE II score appear to be good predictive values for mortality in COVID-19 infection. The dNLR value was more effective than other biomarkers in estimating mortality due to COVID-19. In our study, the cut-off value for dNLR was 3.64.

Aim: The incidence of adverse postoperative outcomes in surgeries for femur fractures is high and is associated with malnutrition. In this study, it was aimed to determine the independent factors for 6-month survival in patients with femur fracture and to evaluate the predictive value of the prognostic nutrition index (PNI). Material and Method: One hundred and sixteen patients operated on only for femoral fracture were divided into survival and non-survival groups according to mortality.Demographic characteristics of the patients, operation data, fracture sites, need for intensive care unit and length of stay, postoperative hospital stay, and preoperative laboratory values, prognostic nutrition indices and mortality were evaluated. Results: Twenty-six (22.4%) of 116 patients who were operated for femoral fracture resulted in 6-month mortality. CRP, albumin, prealbumin, crp/albumin ratio and PNI values at admission were independent risk factors for postoperative mortality (p=0.014, p

Background Our aim in this observational prospective study is to determine whether the prone position has an effect on intracranial pressure, by performing ultrasound-guided ONSD (Optic Nerve Sheath Diameter) measurements in patients with acute respiratory distress syndrome (ARDS) ventilated in the prone position. Methods Patients hospitalized in the intensive care unit with a diagnosis of ARDS who were placed in the prone position for 24 h during their treatment were included in the study. Standardized sedation and neuromuscular blockade were applied to all patients in the prone position. Mechanical ventilation settings were standardized. Demographic data and patients’ pCO 2 , pO 2 , PaO 2 /FiO 2 , SpO 2 , right and left ONSD data, and complications were recorded at certain times over 24 h. Results The evaluation of 24-hour prone-position data of patients with ARDS showed no significant increase in ONSD. There was no significant difference in pCO 2 values either. PaO 2 /FiO 2 and pO 2 values demonstrated significant cumulative increases at all times. Post-prone SPO2 values at the 8th hour and later were significantly higher when compared to baseline (p < 0.001). Conclusion As a result of this study, it appears that the prone position does not increase intracranial pressure during the first 24 h and can be safely utilized, given the administration of appropriate sedation, neuromuscular blockade, and mechanical ventilation strategy. ONSD measurements may increase the safety of monitoring in patients ventilated in the prone position.

Aim: Malnutrition can increase the frequency of infections by reducing the immune system response. Parenteral nutrition (PN) is considered an important treatment for patients who cannot receive adequate oral or enteral nutrition. The contents of nutritional products may be different. In this study, we aimed to investigate the effects of soy-based and olive oil-based parenteral nutrition products on infection parameters. Material and Method: A total of 82 patients were included in the study, 50 of which were soy (Group 2) and 32 were olive-based (Group 1) parenteral nutrition. Patient files and laboratory results were reviewed. Age, gender, 1st, 7th, 14th and 21st days in intensive care, leukocyte and platelet counts, Neutrophil lymphocyte ratio (NLR), C-Reactive Protein (CRP) values, Acute Physiology and Chronic Health Evaluation (Apache II) score and first blood culture results after hospitalization were recorded. Results: The 7th and 21st day CRP values in Group 1 were statistically significantly lower than the 7th and 21st days CRP values in Group 2. In Group 1, growth in blood culture was statistically significantly lower and in Group 2 there was a statistically significant early growth. Conclusion: As a result, it was found that olive oil-based lipid-containing nutritional solutions were more advantageous in terms of infection on intensıve care than soy-based nutrition products. It was concluded that patients who received postoperative mechanical ventilator support fed with olive oil-based parenteral nutrition products had less infectious growth.