Service 135 Latest Publications in Cytometry Part A You Should Not Miss 139 News / Ticker 141 Meetings and Conferences 121 Imprint 143 Guidelines for Authors Thrombozytentransfusion Review Article 102 Effektivität und Nebenwirkungen der Thrombozytentransfusion – produktspezifische Unterschiede Hellstern, P. (Ludwigshafen) Originalarbeiten 106 Signifikant erhöhte Spenderexposition und erhöhte Infektionsraten als unmittelbare Folge eines generellen Wechsels vom AphererseThrombozytenkonzentrat zum PoolThrombozytenkonzentrat Heuft, H.-G.; Mende, W.; Blasczyk, R. (Hannover) 114 Versorgung mit Thrombozytenkonzentraten aus der Sicht des Blutspendedienstes des Bayrischen Roten Kreuzes Weinauer, F. (München) 118 Französische Hämovigilanzdaten zur Thrombozytentransfusion Willaert, B.; Vo Mai, M.-P.; Caldani, C. (Saint-Denis) Klinische Information 122 Malaria Arbeitskreis Blut, Untergruppe «Bewertung Blutassoziierter Krankheitserreger» Abstract Service 135 Aktuelle Veröffentlichungen in Cytometry Part AService 135 Aktuelle Veröffentlichungen in Cytometry Part A 139 News / Ticker 141 Tagungen und Kongresse 121 Impressum 142 Hinweise für Autoren Einen Ausblick auf den Inhalt der kommenden Hefte finden Sie auf Seite 144. Forthcoming Papers are listed on page 144. 066_068_Inhalt_2_08:066_068_Inhalt_2_08 27.03.2008 7:05 Uhr Seite 68

The French Hemovigilance Network has been established in 1994 and records all adverse events associated with the transfusion of a labile blood products ( LBP) regardless of their severity. From 1994 to 2006 35,423,172 LBP were issued, 85,812 adverse transfusion reactions notified, and 139 cases of transfusion related acute lung injury ( TRALI) observed. The LBP most at risk is fresh frozen plasma ( FFP), followed by platelets concentrates ( PC) and packed red cells ( PRC). However, because the use of FFP is not frequent in France, it only accounts for about 10% of TRALI, whereas PRC and PC are involved in the remaining cases. In no case, pooled FFP treated with solvent-detergent were involved. Patients' profiles are peculiar with a high disease burden. Therefore, targeting a prevention policy only on FFP would result in a marginal reduction of TRALI in France.

Background: ABO incompatibilities (ABOi) usually result from the failure to comply with Standard Operating Procedures (SOP). Continuous training (CT) is the main way to ensure their proper use in ultra-high security systems like civil aviation but little is known for transfusion. In France, SOP include a Beth-Vincent test at the bedside before the transfusion of Packed Red Cells (PRC). At the hospitals, Hemovigilance Officers (HO) are in charge of transfusion safety along with the settlement of traceability and the notification of all Adverse Effects (AE). If SOP and CT are requested by Law since 1993 for blood banks, they are only advised for hospitals even though the bedside Beth-Vincent test requires a special training. However, HO have more and more transposed the model of blood banks in hospitals especially since 2000. Objective: to describe time-trends of ABOi observed in e-fit, the French Hemovigilance database. Population and methods: All AE with “acute ABOi” as the final diagnostic were considered. Time-trends were studied according to the Box and Jenkins model (ARMA).