The polynuclear complex [{mu-C1,C4,N,N ''-C6H2{C(H)=N(Bu-n)}(2)-2,5}{Pd(mu-OAc)}](2) (I) reacts with tbbpy (4,4 '-di-tert-butyl-2,2 '-bipyridine) and TlOTf to form the dinuclear complex [{mu-C1,C4,N,N ''-C6H2{C(H)=N(Bu-n)}(2)-2,5}{Pd(tbbpy)}(2)] (1). The hydrolysis of I with acetic acid in a 5:1 acetone/water mixture, in the presence of two equivalents of tbbpy and excess NaX (X = Br, I), yields the dipalladated terephthalaldehyde complexes [C6H2{PdX(tbbpy)}(2)-1,4-(CHO)(2)-2,5] [X = Br (2a), X = I (2b)], which are the first fully characterized complexes of this type. The reaction of 2a,b with CO results in the insertion of CO into both aryl-Pd bonds, forming [C6H2{C(O){PdX(tbbpy)}}(2)-1,4-(CHO)(2)-2,5] [X = Br (3a), X = I (3b)], which are the first examples of complexes with CO inserted into two separate aryl-metal bonds involving the same ligand. The bromo complex 2a reacts with excess XylNC in acetone, causing the precipitation of the dinuclear complex 2,3,6,7-tetrahydrobenzo[1,2-c:4,5-c ']dipyrrole-1,5-dione-2,6-dixylyl-3,7-bis{=C(NHXyl)-C(=NXyl)-[PdBr(CNXyl)(2)]} (4), which is the result of the insertion of three molecules of the isocyanide into each aryl-Pd bond and the nucleophilic attack of one of them at each formyl group. When complex 4 reacts with TlOTf and residual water in 1,2-dichloroethane at 70 degrees C, depalladation occurs, and the organic compound 2,3,6,7-tetrahydrobenzo[1,2-c:4,5-c ']dipyrrole-1,5-dione-2,6-dixylyl-3,7-bis{=C(NHXyl)-C(O)NHXyl} (5) can be isolated. The crystal structures of 14CHCl(3), 42CH(2)Cl(2)3hexane, and 52CDCl(3) have been determined by X-ray crystallography.

The first synthesis of the marine natural product cyanogramide D is reported. The key step is the acetylation of a beta-carboline N-oxide, followed by acetyl migration. Since in this particular case it was not possible to incorporate the styryl side chain by Buchwald coupling, a phenylethanolamine side chain was attached, which was dehydrated with Martin's sulfurane after assembly of the tetracycle. Pentacyclic products were obtained under Appel conditions. The synthesis will facilitate the exploration of the biomimetic oxidative spirocyclization of cyanogramide D to the spirooxindole cyanogramide.

The compounds 2',3',4',6'-tetra-O-acetyl-β-d-gluco-pyranosyl N'-cyano-N-phenyl-carbamimido-thio-ate (C22H25N3O9S, 5a), 2',3',4',6'-tetra-O-acetyl-β-d-galacto-pyranosyl N'-cyano-N-phenyl-carbamimido-thio-ate, (C22H25N3O9S, 5b), 2',3',4',6'-tetra-O-acetyl-β-d-galacto-pyranosyl N'-cyano-N-methyl-carbamimido-thio-ate (C17H23N3O9S, 5c), and 2',3',4',6'-tetra-O-acetyl-β-d-galacto-pyranosyl N'-cyano-N-p-tolyl-carbamimido-thio-ate (C23H27N3O9S, 5d) all crystallize in P212121 with Z = 4. For all four structures, the configuration across the central (formal) C=N(CN) double bond of the carbamimido-thio-ate group is Z. The torsion angles C5-O1-C1-S (standard sugar numbering) are all close to 180°, confirming the β position of the substituent. Compound 5b involves an intra-molecular hydrogen bond N-H⋯O1; in 5c this contact is the weaker branch of a three-centre inter-action, whereas in 5a and 5d the H⋯O distances are much longer and do not represent significant inter-actions. The C-N bond lengths at the central carbon atom of the carbamimido-thio-ate group are almost equal. All C-O-C=O torsion angles of the acetyl groups correspond to a synperiplanar geometry, but otherwise all four mol-ecules display a high degree of conformational flexibility, with many widely differing torsion angles for equivalent groups. In the crystal packing, 5a, 5c and 5d form layer structures involving the classical hydrogen bond N-H⋯Ncyano and a variety of 'weak' hydrogen bonds C-H⋯O or C-H⋯S. The packing of 5b is almost featureless and involves a large number of borderline 'weak' hydrogen bonds. In an appendix, a potted history of wavelength preferences for structure determination is presented and it is recommended that, even for small organic crystals in non-centrosymmetric space groups, the use of Mo radiation should be considered.

The compounds 2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyl N′-cyano-N-phenylcarbamimidothioate (C22H25N3O9S, 5a), 2′,3′,4′,6′-tetra-O-acetyl-β-D-galactopyranosyl N′-cyano-N-phenylcarbamimidothioate, (C22H25N3O9S, 5b), 2′,3′,4′,6′-tetra-O-acetyl-β-D-galactopyranosyl N′-cyano-N-methylcarbamimidothioate (C17H23N3O9S, 5c), and 2′,3′,4′,6′-tetra-O-acetyl-β-D-galactopyranosyl N′-cyano-N-p-tolylcarbamimidothioate (C23H27N3O9S, 5d) all crystallize in P212121 with Z = 4. For all four structures, the configuration across the central (formal) C=N(CN) double bond of the carbamimidothioate group is Z. The torsion angles C5—O1—C1—S (standard sugar numbering) are all close to 180°, confirming the β position of the substituent. Compound 5b involves an intramolecular hydrogen bond N—H...O1; in 5c this contact is the weaker branch of a three-centre interaction, whereas in 5a and 5d the H...O distances are much longer and do not represent significant interactions. The C—N bond lengths at the central carbon atom of the carbamimidothioate group are almost equal. All C—O—C=O torsion angles of the acetyl groups correspond to a synperiplanar geometry, but otherwise all four molecules display a high degree of conformational flexibility, with many widely differing torsion angles for equivalent groups. In the crystal packing, 5a, 5c and 5d form layer structures involving the classical hydrogen bond N—H...Ncyano and a variety of ‘weak’ hydrogen bonds C—H...O or C—H...S. The packing of 5b is almost featureless and involves a large number of borderline ‘weak’ hydrogen bonds. In an appendix, a potted history of wavelength preferences for structure determination is presented and it is recommended that, even for small organic crystals in non-centrosymmetric space groups, the use of Mo radiation should be considered.

Bis(2-methylpyridine)gold(I) dibromidoaurate(I), [Au(C6H7N)2][AuBr2], (1), crystallizes in space group C2/c with Z = 4. Both gold atoms lie on twofold axes and are connected by an aurophilic contact. A second aurophilic contact leads to infinite chains of alternating cations and anions parallel to the b axis, and the residues are further connected by a short H...Au contact and a borderline Br...Br contact. Bis(3-methylpyridine)gold(I) dibromidoaurate(I), [Au(C6H7N)2][AuBr2], (2), crystallizes in space group C2/m with Z = 2. Both gold atoms lie on special positions with symmetry 2/m and are connected by an aurophilic contact; all other atoms except for one methyl hydrogen lie in mirror planes. The extended structure is closely analogous to that of 1, although the structures are formally not isotypic. Bis(3,5-dimethylpyridine)gold(I) dichloridoaurate(I), [Au(C7H9N)2][AuCl2], (3) crystallizes in space group P\overline{1} with Z = 2. The cation lies on a general position, and there are two independent anions in which the gold atoms lie on inversion centres. The cation and one anion associate via three short H...Cl contacts to form a ribbon structure parallel to the b axis; aurophilic contacts link adjacent ribbons. Bis(3,5-dimethylpyridine)gold(I) dibromidoaurate(I), [Au(C7H9N)2][AuBr2], (4) is isotypic to 3. Attempts to make similar compounds involving 2-bromopyridine led instead to 2-bromopyridinium dibromidoaurate(I)–2-bromopyridine (1/1), (C5H5BrN)[AuBr2]·C5H4BrN, (5), which crystallizes in space group P\overline{1} with Z = 2; all atoms lie on general positions. The 2-bromopyridinium cation is linked to the 2-bromopyridine molecule by an N—H...N hydrogen bond. Two formula units aggregate to form inversion-symmetric dimers involving Br...Br, Au...Br and H...Br contacts.

The structures of seven gold(III) halide derivatives of general formula LAuX 3 (L = methylpyridines or dimethylpyridines, X = Cl or Br) are presented: trichlorido(2-methylpyridine)gold(III), [AuCl3(C6H7N)], 1 (as two polymorphs 1a and 1b); tribromido(2-methylpyridine)gold(III), [AuBr3(C6H7N)], 2; tribromido(3-methylpyridine)gold(III), [AuBr3(C6H7N)], 3; tribromido(2,4-dimethylpyridine)gold(III), [AuBr3(C7H9N)], 4; trichlorido(3,5-dimethylpyridine)gold(III), [AuCl3(C7H9N)], 5; tribromido(3,5-dimethylpyridine)gold(III), [AuBr3(C7H9N)], 6, and trichlorido(2,6-dimethylpyridine)gold(III), [AuCl3(C7H9N)], 7. Additionally, the structure of 8, the 1:1 adduct of 2 and 6, [AuBr3(C6H7N)]·[AuBr3(C7H9N)], is included. All the structures crystallize solvent-free, and all have Z′ = 1 except for 5 and 7, which display crystallographic twofold rotation symmetry, and 4, which has Z′ = 2. 1a and 2 are isotypic. The coordination geometry at the gold(III) atoms is, as expected, square-planar. Four of the crystals (1a, 1b, 2 and 8) were non-merohedral twins, and these structures were refined using the ‘HKLF 5’ method. The largest interplanar angles between the pyridine ring and the coordination plane are observed for those structures with a 2-methyl substituent of the pyridine ring. The Au—N bonds are consistently longer trans to Br (average 2.059 Å) than trans to Cl (average 2.036 Å). In the crystal packing, a frequent feature is the offset-stacked and approximately rectangular dimeric moiety (Au—X)2, with antiparallel Au—X bonds linked by Au...X contacts at the vacant positions axial to the coordination plane. The dimers are connected by further secondary interactions (Au...X or X...X contacts, `weak' C—H...X hydrogen bonds) to form chain, double chain (`ladder') or layer structures, and in several cases linked again in the third dimension. Only 1b and 7 contain no offset dimers; these structures instead involve C—H...Cl hydrogen bonds combined with Cl...Cl contacts (1b) or Cl...π contacts (7). The packing patterns of seven further complexes LAuX 3 involving simple pyridines (taken from the Cambridge Structural Database) are compared with those of 1–8.

The structures of fourteen halochalcogenylphosphonium tetrahalogenidoaurates(III), phosphane chalcogenide derivatives with general formula [R13–nR2nPEX][AuX4] (R1 = t-butyl; R2 = isopropyl; n = 0 to 3; E = S or Se; X = Cl or Br) are presented. The eight possible chlorido derivatives are: 17a, n = 3, E = S; 18a, n = 2, E = S; 19a, n = 1, E = S; 20a, n = 0, E = S; 21a, n = 3, E = Se; 22a, n = 2, E = Se; 23a, n = 1, E = Se; and 24a, n = 0, E = Se, and the corresponding bromido derivatives are 17b–24b in the same order. Structures were obtained for all compounds except for the tri-t-butyl derivatives 24a and 24b. Isotypy is observed for 18a/18b/22a/22b, 19a/23a, 17b/21b and 19b/23b. In eleven of the compounds, X...X contacts (mostly very short) are observed between the cation and anion, whereby the E—X...X groups are approximately linear and the X...X—Au angles approximately 90°. The exceptions are 17a, 19a and 23a, which instead display short E...X contacts. Bond lengths in the cations correspond to single bonds P—E and E—X. For each group with constant E and X, the P—E—X bond-angle values increase monotonically with the steric bulk of the alkyl groups. The packing is analysed in terms of E...X, X...X (some between anions alone), H...X and H...Au contacts. Even for isotypic compounds, some significant differences can be discerned.

Luminosity determination within the ALICE experiment is based on the measurement, in van der Meer scans, of the cross sections for visible processes involving one or more detectors (visible cross sections). In 2015 and 2018, the Large Hadron Collider provided Pb$-$Pb collisions at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\rm NN}} = 5.02$ TeV. Two visible cross sections, associated with particle detection in the Zero Degree Calorimeter (ZDC) and in the V0 detector, were measured in a van der Meer scan. This article describes the experimental set-up and the analysis procedure, and presents the measurement results. The analysis involves a comprehensive study of beam-related effects and an improved fitting procedure, compared to previous ALICE studies, for the extraction of the visible cross section. The resulting uncertainty of both the ZDC-based and the V0-based luminosity measurement for the full sample is 2.5%. The inelastic cross section for hadronic interactions in Pb$-$Pb collisions at $\sqrt{s_{\rm NN}} = 5.02$ TeV, obtained by efficiency correction of the V0-based visible cross section, was measured to be $7.67 \pm 0.25$ b, in agreement with predictions using the Glauber model.

Multiplicity ($N_{\rm ch}$) distributions and transverse momentum ($p_{\rm T}$) spectra of inclusive primary charged particles in the kinematic range of $|\eta| < 0.8$ and 0.15 GeV/$c$ $< p_{T} <$ 10 GeV/$c$ are reported for pp, p-Pb, Xe-Xe and Pb-Pb collisions at centre-of-mass energies per nucleon pair ranging from $\sqrt{s_{\rm NN}} = 2.76$ TeV up to $13$ TeV. A sequential two-dimensional unfolding procedure is used to extract the correlation between the transverse momentum of primary charged particles and the charged-particle multiplicity of the corresponding collision. This correlation sharply characterises important features of the final state of a collision and, therefore, can be used as a stringent test of theoretical models. The multiplicity distributions as well as the mean and standard deviation derived from the $p_{\rm T}$ spectra are compared to state-of-the-art model predictions. Providing these fundamental observables of bulk particle production consistently across a wide range of collision energies and system sizes can serve as an important input for tuning Monte Carlo event generators.

The production yields of non-prompt D-s(+) smesons, namely D-s(+) smesons from beauty-hadron decays, were measured for the first time as a function of the transverse momentum (p(T)) at midrapidity (|y| < 0.5) in central and semi-central Pb-Pb collisions at a centre-of-mass energy per nucleon pair root s(NN)= 5.02TeVwith the ALICE experiment at the LHC. The D-s(+) smesons and their charge conjugates were reconstructed from the hadronic decay channel D-s(+) -> phi pi+, with phi -> K- K+, in the 4 < pT< 36GeV/cand 2 < pT< 24GeV/cintervals for the 0-10% and 30-50% centrality classes, respectively. The measured yields of non-prompt D-s(+) smesons are compared to those of prompt D-s(+) sand non-prompt D-0 mesons by calculating the ratios of the production yields in Pb-Pb collisions and the nuclear modification factor R-AA. The ratio between the R-AA of non-prompt D-s(+) sand prompt D-s(+) smesons, and that between the R-AA of non-prompt D-s(+) sand non-prompt D-0 mesons in central Pb-Pb collisions are found to be on average higher than unity in the 4 < p(T) < 12GeV/c interval with a statistical significance of about 1.6 sigma and 1.7 sigma, respectively. The measured R-AA ratios are compared with the predictions of theoretical models of heavy-quark transport in a hydrodynamically expanding QGP that incorporate hadronisation via quark recombination. (c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP3.

Measurements of the elliptic flow coefficient relative to the collision plane defined by the spectator neutrons $v_2${$\Psi_{\rm SP}$} in collisions of Pb ions at center-of-mass energy per nucleon-nucleon pair $\sqrt{s_{\rm NN}}$=2.76 TeV and Xe ions at $\sqrt{s_{\rm NN}}$=5.44 TeV are reported. The results are presented for charged particles produced at midrapidity as a function of centrality and transverse momentum. The ratio between $v_2${$\Psi_{\rm SP}$} and the elliptic flow coefficient relative to the participant plane $v_2${4}, estimated using four-particle correlations, deviates by up to 20% from unity depending on centrality. This observation differs strongly from the magnitude of the corresponding eccentricity ratios predicted by the TRENTo and the elliptic power models of initial state fluctuations that are tuned to describe the participant plane anisotropies. The differences can be interpreted as a decorrelation of the neutron spectator plane and the reaction plane because of fragmentation of the remnants from the colliding nuclei, which points to an incompleteness of current models of initial state fluctuations. A significant transverse momentum dependence of the ratio $v_2${$\Psi_{\rm SP}$}/$v_2${4} is observed in all but the most central collisions, which may help to understand whether momentum anisotropies at low and intermediate transverse momentum have a common origin in initial state fluctuations. The ratios of $v_2${$\Psi_{\rm SP}$} and $v_2${4} to the corresponding initial state eccentricities for Xe-Xe and Pb-Pb collisions at similar initial entropy density show a difference of $(7.0 \pm 0.9)$% with an additional variation of +1.8% when including RHIC data in the TRENTo parameter extraction. These observations provide new experimental constraints for viscous effects in the hydrodynamic modeling of the expanding quark-gluon plasma.

Fluctuation measurements are important sources of information on the mechanism of particle production at LHC energies. This article reports the first experimental results on third-order cumulants of the net-proton distributions in Pb-Pb collisions at a center-of-mass energy root s(NN) = 5.02 TeV recorded by the ALICE detector. The results on the second-order cumulants of net-proton distributions at root s(NN) = 2.76 and 5.02TeV are also discussed in view of effects due to the global and local baryon number conservation. The results demonstrate the presence of long-range rapidity correlations between protons and antiprotons. Such correlations originate from the early phase of the collision. The experimental results are compared with HIJING and EPOS model calculations, and the dependence of the fluctuation measurements on the phase-space coverage is examined in the context of lattice quantum chromodynamics (LQCD) and hadron resonance gas (HRG) model estimations. The measured third-order cumulants are consistent with zero within experimental uncertainties of about 4% and are described well by LQCD and HRG predictions. (c) 2022 The Author. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP(3).

Measurements of (anti)proton, (anti)deuteron, and (anti)3He production in the rapidity range -1 < y < 0 as a function of the transverse momentum and event multiplicity in p-Pb collisions at a center-of-mass energy per nucleon-nucleon pair root s(NN) = 8.16 TeV are presented. The coalescence parameters B2 and B3, measured as a function of the transverse momentum per nucleon and of the mean charged-particle multiplicity density, confirm a smooth evolution from low to high multiplicity across different collision systems and energies. The ratios between (anti)deuteron and (anti)3He yields and those of (anti)protons are also reported as a function of the mean charged-particle multiplicity density. A comparison with the predictions of the statistical hadronization and coalescence models for different collision systems and center-of-mass energies favors the coalescence description for the deuteron-to-proton yield ratio with respect to the canonical statistical model. (c) 2023 European Organization for Nuclear Research. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons .org /licenses /by /4 .0/). Funded by SCOAP3.

This letter reports measurements which characterize the underlying event associated with hard scatterings at mid-pseudorapidity (|eta| < 0.8) in pp, p-Pband Pb-Pb collisions at centre-of-mass energy per nucleon pair, root sNN= 5.02TeV. The measurements are performed with ALICE at the LHC. Different multiplicity classes are defined based on the event activity measured at forward rapidities. The hard scatterings are identified by the leading particle defined as the charged particle with the largest transverse momentum (pT) in the collision and having 8< pT< 15GeV/c. The p(T) spectra of associated particles (0.5= pT< 6GeV/c) are measured in different azimuthal regions defined with respect to the leading particle direction: toward, transverse, and away. The associated charged particle yields in the transverse region are subtracted from those of the away and toward regions. The remaining jet-like yields are reported as a function of the multiplicity measured in the transverse region. The measurements show a suppression of the jet-like yield in the away region and an enhancement of high-p(T) associated particles in the toward region in central Pb-Pb collisions, as compared to minimum-bias pp collisions. These observations are consistent with previous measurements that used two-particle correlations, and with an interpretation in terms of parton energy loss in a high-density quark gluon plasma. These yield modifications vanish in peripheral Pb-Pb collisions and are not observed in either high-multiplicity pp or p-Pb collisions. (c) 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP(3).

The performance of the electromagnetic calorimeter of the ALICE experiment during operation in 2010–2018 at the Large Hadron Collider is presented. After a short introduction into the design, readout, and trigger capabilities of the detector, the procedures for data taking, reconstruction, and validation are explained. The methods used for the calibration and various derived corrections are presented in detail. Subsequently, the capabilities of the calorimeter to reconstruct and measure photons, light mesons, electrons and jets are discussed. The performance of the calorimeter is illustrated mainly with data obtained with test beams at the Proton Synchrotron and Super Proton Synchrotron or in proton-proton collisions at √s = 13 TeV, and compared to simulations.

Here, we present a new route to dyes of the BODIPY family. We first built up a N-Boc-protected dipyrromethene scaffold via an aminopalladation cascade. Subsequentially, the pyrrole moiety was deprotected and the BF2 unit inserted. Depending on the terminating reaction, BODIPYs with either aryl or alkynyl moieties were accessible.

The first experimental information on the strong interaction between Λ and Ξ− strange baryons is presented in this Letter. The correlation function of Λ–Ξ− and Λ‾–Ξ‾+ pairs produced in high-multiplicity proton–proton (pp) collisions at s=13 TeV at the LHC is measured as a function of the relative momentum of the pair. The femtoscopy method is used to calculate the correlation function, which is then compared with theoretical expectations obtained using a meson exchange model, chiral effective field theory, and Lattice QCD calculations close to the physical point. Data support predictions of small scattering parameters while discarding versions with large ones, thus suggesting a weak Λ–Ξ− interaction. The limited statistical significance of the data does not yet allow one to constrain the effects of coupled channels like Σ–Ξ and N–Ω.

The production of prompt Lambda(+)(c) baryons has been measured at midrapidity in the transverse momentum interval 0 < pT < 1 GeV/c for the first time, in pp and p-Pb collisions at a center-of-mass energy per nucleon-nucleon collision root s(NN) = 5.02 TeV. The measurement was performed in the decay channel Lambda(+)(c) . pK0 S by applying new decay reconstruction techniques using a Kalman-Filter vertexing algorithm and adopting a machine-learning approach for the candidate selection. The pT -integrated Lambda(+)(c) production cross sections in both collision systems were determined and used along with the measured yields in Pb-Pb collisions to compute the pT -integrated nuclear modification factors RpPb and RAA of Lambda(+)(c) baryons, which are compared to model calculations that consider nuclear modification of the parton distribution functions. The Lambda(+)(c) /D0 baryon-to-meson yield ratio is reported for pp and p-Pb collisions. Comparisons with models that include modified hadronization processes are presented, and the implications of the results on the understanding of charm hadronization in hadronic collisions are discussed. A significant (3.7s) modification of the mean transverse momentum of Lambda(+)(c) baryons is seen in p-Pb collisions with respect to pp collisions, while the pT -integrated Lambda(+)(c) /D0 yield ratio was found to be consistent between the two collision systems within the uncertainties.

Two-particle correlations with K-S(0), Lambda/(Lambda) over bar, and charged hadrons as trigger particles in the transverse momentum range 8 3 GeV/c as expected from strong in-medium energy loss, while an enhancement develops at low p(T), assoc on both the near and away sides, reaching I-AA approximate to 1.8 and 2.7 respectively. These findings are in good agreement with previous ALICE measurements from two-particle correlations triggered by neutral pions (pi(0)-h) and charged hadrons (h-h) in Pb-Pb collisions at root s(NN) = 2.76 TeV. Moreover, the correlations with K-S(0) mesons and Lambda/(Lambda) over bar baryons as trigger particles are compared to those of inclusive charged hadrons. The results are compared with the predictions of Monte Carlo models.

The production of prompt $\rm \Lambda_{\rm c}^{+}$ baryons at midrapidity ($|y|<0.5$) was measured in central (0-10%) and mid-central (30-50%) Pb-Pb collisions at the center-of-mass energy per nucleon-nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the ALICE detector. The $\rm \Lambda_{\rm c}^{+}$ production yield, the $\rm \Lambda_{\rm c}^{+}$/D$^0$ production ratio, and the $\rm \Lambda_{\rm c}^{+}$ nuclear modification factor $R_{\rm AA}$ are reported. The results are more precise and more differential in transverse momentum ($p_{\rm T}$) and centrality with respect to previous measurements. The $\rm \Lambda_{\rm c}^{+}$/D$^0$ ratio, which is enhanced with respect to the pp measurement for $4< p_{\rm T} < 8$ GeV/$c$, is described by theoretical calculations that model the charm-quark transport in the quark-gluon plasma and include hadronization via both coalescence and fragmentation mechanisms.