Ziel/Aim: In VISION, [177Lu]Lu-PSMA-617 (177Lu-PSMA-617) plus standard of care (SoC) significantly improved overall survival and radiographic progression-free survival in patients (pts) with PSMA-positive metastatic castration-resistant prostate cancer. In the VISION dosimetry sub-study, 177Lu-PSMA-617 had a good safety profile with low radiotoxicity. Here, we present the tumor dosimetry for 177Lu-PSMA-617 across cycles 1-6.