The Globally Harmonised System of Classification (GHS) is a framework within which the intrinsic hazards of substances may be determined and communicated. It is not a legislative instrument per se, but is enacted into national legislation with the appropriate legislative instruments. GHS covers many aspects of effects upon health and the environment, including adverse effects upon sexual function and fertility or on development. Classification for these effects is based upon observations in humans or from properly designed experiments in animals, although only the latter is covered herein. The decision to classify a substance based upon experimental data, and the category of classification ascribed, is determined by the level of evidence that is available for an adverse effect on sexual function and fertility or on development that does not arise as a secondary non-specific consequence of other toxic effect. This document offers guidance on the determination of level of concern as a measure of adversity, and the level of evidence to ascribe classification based on data from tests in laboratory animals.

Community Health StudiesVolume 4, Issue 3 p. 197-200 Free to Read COMMUNITY PREFERENCES FOR SEX OF DOCTOR Peter Lee, Peter Lee Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorMichele Bellarot-Lazonde, Michele Bellarot-Lazonde Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorJim Farrent, Jim Farrent Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorJeff Harvey, Jeff Harvey Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorBruce Mugford, Bruce Mugford Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorStuart Reader, Stuart Reader Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorCelia Williamson, Celia Williamson Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorCarolyn Wong, Carolyn Wong Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this author Peter Lee, Peter Lee Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorMichele Bellarot-Lazonde, Michele Bellarot-Lazonde Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorJim Farrent, Jim Farrent Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorJeff Harvey, Jeff Harvey Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorBruce Mugford, Bruce Mugford Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorStuart Reader, Stuart Reader Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorCelia Williamson, Celia Williamson Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this authorCarolyn Wong, Carolyn Wong Student Office, Flinders Medical Centre, Bedford Park, S.A.Search for more papers by this author First published: October 1980 https://doi.org/10.1111/j.1753-6405.1980.tb00298.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume4, Issue3October 1980Pages 197-200 RelatedInformation