AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Sulfated mono- and disaccharides were synthesised by a novel sulfation method via regioselective activation of the saccharides to their dibutyltin stannylene acetals, followed by treatment with sulfur trioxide-trimethylamine. This methodology was applied to the synthesis of 3'-sulfated lactosides 15 and 23, galactosylceramide sulfatide 3 and 2'-sulfated maltosides 30, 32 and 34.

Observations of Capybaras, Hydrochoerus hydrochaeris , in the Venezuelan savannah during the dry season show that the sexes differ in the structure and size of their scent glands and in the way they deploy odours. Males have a greatly enlarged nose gland or morrillo, from which they smear copious secretion on vegetation. They also have detachable, secretion‐coated hairs within their large anal pockets. Vegetation marked by the morrillo may also be marked by dragging the anal pockets across it, and by urination. The morrillos of females resemble those of males, but are poorly developed and infrequently used. The anal pockets of females are highly developed, and differ externally from those of males in having a more ampulla‐like shape and in lacking detachable hairs (osmetrichia). During the dry season, scent marks of all types made by members of both sexes seem to be deployed throughout the Capybaras home range. At this time, males mark more frequently than females, and larger animals have larger, more active morrillos and anal glands than smaller ones, and probably use them more often. The histology of both glands is described: both are composed of sebaceous tissue. The detachable hairs of males were examined through scanning electron microscopy and found to be coated in regular layers of a largely crystaline deposit. The structure of the hairs may be adapted to retain secretion. The chemistry of the secretion of male morrillos and female anal pockets was investigated. The two secretions are different, although both contain lipids including sterols and/or terpenes, and both contain amines and amino acids. The same compounds were generally represented in the secretion of the same gland from different individuals, but in different quantities and proportions, hence suggesting that individual recognition is possible on the basis of a “chemical fingerprint”. The most volatile substance from the male morrillo was a hydrocarbon C 30 H 50 , whereas the bulk of the secretion is a complex mixture of esters.

AbstractThe fragmentation of simple alkyl acridines closely resembles that of the analogous quinoline derivatives. Interaction between the heteroatom and a 4‐alkyl substituent dramatically influences the fragmentation pattern with resultant γ‐cleavage or rearrangement to the heteroatom and corresponding elimination of an alkene fragment. The fragmentation of the 9‐chloroalkylacridines closely resembles that of the acridines with the loss of the clorine atom superposed on the alkylacridine fragmentation. Redistribution of the centre of apparent charge localization occurs for the acridones with a tendency for interaction with the 9‐position.

AbstractThe mass spectral behaviour of a series of naturally occurring and synthetic 3,4‐A‐seco‐triterpenes has been examined and fragmentations characteristic of the 3,4‐A‐seco function observed. Deuterium labelling has been used to investigate the origins of their characteristic fragments.

Die Rimino-Phenazin-Verbindung (Präparat B663 — Lampren® Clofazimine) mit starker Wirkung gegenMycobacterium leprae wurde 41/2 Monate an Mäuse verfüttert. Lichtmikroskopisch, dünnschichtchromatographisch und massenspektrometrisch wurde festgestellt, dass die B663-Kristalle im Cytoplasma der Makrophagen mit den in der Grundsubstanz vorhandenen identisch sind.

AbstractStudies of both high and low resolution spectra, and of metastable decompositions occurring in both the first and second field‐free regions of the mass spectrometer have led to a postulated scheme for the fragmentation of acridine under electron‐impact. There is no specific loss of label from either [9‐2H1]acridine or [4,5‐2H2]acridine in any fragmentation, nor is there any total scrambling of label in either molecular ion prior to loss of HCN. There is certainly some degree of scrambling preceding HCN loss from [M]+˙ at 70 eV, but this does not involve the 9‐H to any detectable extent. There is no strong evidence for the acridine molecular ion having the same structure as that of four other C13H9N isomers.

Chemischer Informationsdienst. Organische ChemieVolume 2, Issue 25 Heterocyclic Compounds ChemInform Abstract: UNTERSUCHUNG DER HONGKONG-RUBIACEEN 8. MITT. STRUKTUR VON SPINOSSAEURE A, EINEM TRITERPENOID-SAPOGENIN AUS RANDIA SPINOSA (THUNB.) POIR. R. T. APLIN, R. T. APLINSearch for more papers by this authorW. H. HUI, W. H. HUISearch for more papers by this authorC. T. HO, C. T. HOSearch for more papers by this authorC. W. YEE, C. W. YEESearch for more papers by this author R. T. APLIN, R. T. APLINSearch for more papers by this authorW. H. HUI, W. H. HUISearch for more papers by this authorC. T. HO, C. T. HOSearch for more papers by this authorC. W. YEE, C. W. YEESearch for more papers by this author First published: June 22, 1971 https://doi.org/10.1002/chin.197125381AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue25June 22, 1971 RelatedInformation

Spinosic acid A, one of the sapogenins from Randia spinosa, has been shown to be 3β, 19β-dihydroxyolean-12-en-28-oic acid. Other sapogenins isolated include oleanolic acid, siaresinolic acid, and another new triterpenoid, spinosic acid B. The sterols, β-sitosterol and stigmasterol have also been obtained.

AbstractDie Ozonolyse des Lupanols (I) und des Lupens (II) führt zum Lupanon (III) (Ausbeute 90%) bzw. zum Norketon (IV).

Die flüchtigen Anteile aus den männlichen Duftorganen von 7 Gattungen der Noctuiden wurden gaschromatographisch identifiziert.

AbstractThe mass spectra of a number of alkyl and aryl acetylenic ketones of the type RCO·CC·CC·R′ have been examined. All the spectra exhibit molecular ions together with the expected intense fragments arising from cleavage α‐to the carbonyl group. The most striking feature of the ketone spectra is the loss of CO from the molecular ion. This process dominates the spectra of the aryl ketones, the spectra below [M – 28]+˙. being virtually identical to those of the corresponding phenylacetylenes. The spectra of the piperidene and/or morpholine adducts of the alkyl ketones are very similar to those of the parent ketone whereas those of the aryl ketones are dominated by the loss HO˙ from the molecular ion. Deuterium labelling has established the site of the hydrogen involved as being the carbons α‐ to the nitrogen of the heterocyclic ring.

AbstractThe mass spectra of six β‐ketoalkylidenephosphoranes have been examined. The spectra all exhibit an electron‐impact induced migration of oxygen to phosphorus reminiscent of their thermal decomposition.

AbstractComparison of the acetyl‐, trifluoroacetyl‐, benzyloxycarbonyl‐, methoxycarbonyl‐, ethoxycarbonyl, methylaminocarbonyl, phenylaminocarbonyl‐, phthanoyl‐, and stearoyl‐derivatives of glycylleucylphenylalanine methyl ester has shown that acetyl derivative is the most volatile. The relative abundances of the sequence ions in the mass spectra od these compounds have been determined and compared: the acetyl derivative provides the best combination of volatility and abundance of sequence ions. Evidence is presented to show that the use of acid‐catalysed esterification procedure for the chemical modification of peptides prior to mas spectrometric investigation can lead to degraded derivatives.

Ozonolysis of methyl acetylbetulinate (II) gives number of products in addition to the nor-ketone (V) formed by the normal fission of the isopropenyl double-bond. They include the Baeyer–Villiger oxidation product (VIII) of the nor-ketone and two trisnor-compounds. In one of these (XVIII) the isopropenyl group has been lost and a Δ18,19 double-bond has been formed at the carbon to which it was attached. In the other (XI) the isopropenyl group has been replaced by hydrogen. A possible mechanism for the formation of these products is discussed.

Spectrometric examination established the structures of the steroids named in the title. In the mass spectrum of one of the ring-D-lactams (the 17-aza-16-oxo-isomer) the base peak arises from the (M– 15) ion, and no other peak has an abundance of more than 8%. Distinction between the ring-A lactams depends upon differentiation, by 1H n.m.r., between the units [graphic omitted]CH·CH2·CO·NH·CH2– and [graphic omitted]CH·CH2·NH·CO·CH2–.

RECENT investigations have shown that benzaldehyde is the chief component of the pheromone extracted from the abdominal scent-brushes of Leucania impura (Huebner), Leucania conigera (Schiffermueller) and Phlogophora meticulosa (Linnaeus).