Organic Mass SpectrometryVolume 28, Issue 3 p. 289-290 OMS Letter Structural characterization of a glycoalkaloid at the femtomole level by means of four-sector tandem mass spectrometry and scanning-array detection† Syd Evans, Syd Evans Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorRod Buchanan, Rod Buchanan Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorAndrew Hoffman, Andrew Hoffman Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorFred A. Mellon, Fred A. Mellon AFRC Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, UKSearch for more papers by this authorKeith R. Price, Keith R. Price AFRC Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, UKSearch for more papers by this authorS. Hall, S. Hall School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorF. C. Walls, F. C. Walls School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorA. L. Burlingame, A. L. Burlingame School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorSu Chen, Su Chen Institute of Mass Spectrometry and Department of Chemistry, University of Warwick, Coventry CV4 7AL, UKSearch for more papers by this authorPeter J. Derrick, Peter J. Derrick Institute of Mass Spectrometry and Department of Chemistry, University of Warwick, Coventry CV4 7AL, UKSearch for more papers by this author Syd Evans, Syd Evans Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorRod Buchanan, Rod Buchanan Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorAndrew Hoffman, Andrew Hoffman Kratos Analytical Ltd, Barton Dock Road, Urmston, Manchester, UKSearch for more papers by this authorFred A. Mellon, Fred A. Mellon AFRC Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, UKSearch for more papers by this authorKeith R. Price, Keith R. Price AFRC Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, UKSearch for more papers by this authorS. Hall, S. Hall School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorF. C. Walls, F. C. Walls School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorA. L. Burlingame, A. L. Burlingame School of Pharmacy, University of California, San Francisco, California 94143, USASearch for more papers by this authorSu Chen, Su Chen Institute of Mass Spectrometry and Department of Chemistry, University of Warwick, Coventry CV4 7AL, UKSearch for more papers by this authorPeter J. Derrick, Peter J. Derrick Institute of Mass Spectrometry and Department of Chemistry, University of Warwick, Coventry CV4 7AL, UKSearch for more papers by this author First published: March 1993 https://doi.org/10.1002/oms.1210280326Citations: 16 † Presented at Kyoto '92 Biological Mass Spectrometry, Kyoto, September 1992. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume28, Issue3Special Issue: Dedicated to Professor Dr H. Budzikiewicz on the Occasion of his 60th BirthdayMarch 1993Pages 289-290 RelatedInformation

This chapter describes detectors. Detectors for mass spectrometers fall into two main categories: direct measurement detectors, which detect the charge arriving at the detector, and multiplier detectors, which use electron multiplication to give a signal of sufficient intensity to enable single-ion detection and rapid scanning. The choice of detector depends on the application. Direct measurement methods are essential for high-accuracy isotope ratio measurements, as the gain of electron multiplier vanes not only with mass but also with the structure of the ion. The simplest way to detect an ion beam is to place a metal plate in its path and measure the charge falling on the plate by connecting it to an amplifier using a large feedback resistor. However, when an ion strikes a surface with the sort of energy typically used in a sector-field mass spectrometer, secondary electrons are produced. The charge associated with an electron leaving a surface has the same magnitude and polarity as a positive ion arriving at the surface, and, typically, several electrons are produced for each incident ion.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacteristics of a multichannel electrooptical detection system and its application to the analysis of large molecules by fast atom bombardment mass spectrometryJohn S. Cottrell and Syd. EvansCite this: Anal. Chem. 1987, 59, 15, 1990–1995Publication Date (Print):August 1, 1987Publication History Published online1 May 2002Published inissue 1 August 1987https://pubs.acs.org/doi/10.1021/ac00142a021https://doi.org/10.1021/ac00142a021research-articleACS PublicationsRequest reuse permissionsArticle Views85Altmetric-Citations79LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Rapid Communications in Mass SpectrometryVolume 1, Issue 1 p. 1-2 Article The application of a multichannel electro-optical detection system to the analysis of large molecules by FAB mass spectrometry John S. Cottrell, Corresponding Author John S. Cottrell Kratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKKratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKSearch for more papers by this authorSyd Evans, Syd Evans Kratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKSearch for more papers by this author John S. Cottrell, Corresponding Author John S. Cottrell Kratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKKratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKSearch for more papers by this authorSyd Evans, Syd Evans Kratos Analytical Instruments, Barton Dock Road, Urmston, Manchester M31 2LD, UKSearch for more papers by this author First published: May 1987 https://doi.org/10.1002/rcm.1290010103Citations: 17AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume1, Issue1May 1987Pages 1-2 RelatedInformation