A 81-year-old black hypertensive patient noted some respiratory distress, cough and dysphagia four days after starting lisinopril. Three days later, with worsening of symptoms, the patient went to the emergency department were angioedema was diagnosed. Shortly after, he went in respiratory and cardiac arrest and CPR was started. The airway was managed with an orotracheal tube and mechanical ventilation was started until full neurologic recover. Corticoid and antihistaminic therapy was also started. On the third ICU day went under self-extubation. Initially there was not any respiratory distress, but slowly on the next two days the patient developed a worsening thoracic pain, stridor with broncospam and subcutaneous emphysema, which led to promptly re-intubation. After a clean thoracic X-ray, a thoracic CT scan revealed anterior herniation of the left lung through 5 fractured ribs, with bilateral air dissection of the muscular plans. The patient underwent surgery, with hernia reduction and prosthesis placement on 3 of 5 broken ribs. This case report describes a rare but known side effect of a commonly used anti-hypertensive drug. The angioedema developed into respiratory arrest and required CPR. This maneuver was life saving, however led to lung herniation, a rare complication in a conscious and non ventilated patient. Traumatic intercostal hernias usually occur medial to the costochondral junction. Eighty percent of lung herniations are secondary to trauma or surgery and the remaining 20% are congenital defects. Lung herniation after CPR is a rare complication end although there are some cases reported, the real percentage is not clear. The usual management of a lung hernia is conservative. Surgery is reserved for large or incarcerated hernias, for those that are intractably and painful, or those that are cosmetically unacceptable. Surgical repair was undertaken in this case because of respiratory failure, incarceration of lung tissue, and pain localized to the defect.