At the beginning of 2003, in Casablanca (Morocco), three persons (two men and one woman) were found dead in different places and in different slots: they were horribly mutilated. The man suspected for the murders was found hanged. We performed DNA analysis for the identification of each victim by comparison with the alleged relatives to test the paternity of the woman's son, to verify the siblings relation, and to discover to whom some hairs belonged that were found on the scene of the 3rd homicide.
The authors report a case of malignant melanoma of the cervix uteri diagnosed in a young 35-year-old patient. Isolated genital bleeding was the beginning symptom. The physical exam showed a cervical dark tumor, with extension into the vagina (superior third), the parametrium was free. Cervical biopsy concluded to a malignant melanoma. No other abnormalities were observed and the tumor was classed stage IIA-FIGO. A total hysterectomy with bilateral annexectomy and pelvic lymphadenectomy was performed. In the way, the patient died after ten months by local and general recurrence. Primitive malignant melanoma of the cervix uteri is rare. Only 39 cases are reported in literature at this day. It is usually initially misdiagnosed mainly in the achromic forms, then the immuno-histochemical study is useful. Its treatment is not well codified and its histogenesis was controversial for a long time.
Les auteurs rapportent un cas de mélanome malin primitif du col utérin chez une patiente de 35 ans, révélé par des métrorragies isolées, de moyenne abondance. L’examen gynécologique a retrouvé une tumeur noirâtre du col atteignant le tiers supérieur du vagin sans atteinte paramétriale, dont la biopsie a conclu à un mélanome malin. La recherche de la lésion primitive et de métastases est resté négative permettant ainsi de conclure à un mélanome malin primitif du col utérin classé stade IIA de la FIGO. Le traitement a consisté en une hystérectomie totale avec annexectomie bilatérale et lymphadénectomie pelvienne. L’évolution a été marquée par le décès de la malade après dix mois de recul dans un tableau de récidive locorégionale et de métastase. Le mélanome malin primitif du col utérin est une entité rare ; seulement 39 cas sont décrits dans la littérature à ce jour. Son diagnostic est souvent initialement erroné surtout dans les cas achromiques, l’étude immunohistochimique est alors d’une grande utilité. Sa thérapeutique n’est pas codifiée et son histogenèse a été longtemps débattue.