Alternative and Complementary TherapiesVol. 18, No. 2 Hops (Humulus lupulus): An Evidence-Based Systematic Review by the Natural Standard Research CollaborationCatherine Ulbricht, Ethan Basch, Samuel Basch, Wendy Chao, Julie Conquer, Dawn Costa, Samantha Culwell, Cynthia Dacey, Jacquelyn Guilford, Paul Hammerness, Elizabeth R.B. Higdon, Richard Isaac, Margaret Lynch, Carolyn Williams Orlando, Erica Rusie, Minney Varghese, Mamta Vora, Regina C. Windsor, and Jen WoodsCatherine UlbrichtSearch for more papers by this author, Ethan BaschSearch for more papers by this author, Samuel BaschSearch for more papers by this author, Wendy ChaoSearch for more papers by this author, Julie ConquerSearch for more papers by this author, Dawn CostaSearch for more papers by this author, Samantha CulwellSearch for more papers by this author, Cynthia DaceySearch for more papers by this author, Jacquelyn GuilfordSearch for more papers by this author, Paul HammernessSearch for more papers by this author, Elizabeth R.B. HigdonSearch for more papers by this author, Richard IsaacSearch for more papers by this author, Margaret LynchSearch for more papers by this author, Carolyn Williams OrlandoSearch for more papers by this author, Erica RusieSearch for more papers by this author, Minney VargheseSearch for more papers by this author, Mamta VoraSearch for more papers by this author, Regina C. WindsorSearch for more papers by this author, and Jen WoodsSearch for more papers by this authorPublished Online:20 Apr 2012https://doi.org/10.1089/act.2012.18204AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetails Volume 18Issue 2Apr 2012 Information© 2012, Mary Ann Liebert, Inc.To cite this article:Catherine Ulbricht, Ethan Basch, Samuel Basch, Wendy Chao, Julie Conquer, Dawn Costa, Samantha Culwell, Cynthia Dacey, Jacquelyn Guilford, Paul Hammerness, Elizabeth R.B. Higdon, Richard Isaac, Margaret Lynch, Carolyn Williams Orlando, Erica Rusie, Minney Varghese, Mamta Vora, Regina C. Windsor, and Jen Woods.Hops (Humulus lupulus): An Evidence-Based Systematic Review by the Natural Standard Research Collaboration.Alternative and Complementary Therapies.Apr 2012.98-108.http://doi.org/10.1089/act.2012.18204Published in Volume: 18 Issue 2: April 20, 2012PDF download

Objective: To assess the prevalence of depression and psychologic disorders and their effect on the quality of life in women with polycystic ovary syndrome. Methods: We performed a PubMed search of major relevant articles published during the period from 1985 to 2009 dealing with polycystic ovary syndrome, associated psychologic morbidity, and the relationship to clinical and biochemical changes affecting the quality of life. Results: In patients with polycystic ovary syndrome, the presence of depression and allied disorders was frequently noted to diminish mental well-being, affect, and self-worth. The symptoms often associated with this syndrome, such as hirsutism, obesity, irregular menses, and self-worth. The symptoms often associated with this syndrome, such as hirsutism, obesity, irregular menses, and subfertility, were a major source of psychologic morbidity. Obesity was the most prevalent cause of mental distress, whereas other features such its hirsutism and infertility were less well defined as major factors. Although the findings in some studies have been inconclusive, the presence of clinically significant eating disorders and a 7-fold increase in the suicide rate have been reported in women with polycystic ovary syndrome. Conclusion: Women with polycystic ovary syndrome have a high risk for depression and affective disorders that impair their quality of life. The presence of obesity, eating disorders, hirsutism, poor self-image, and a significant suicide rate makes evaluation of their emotional state an integral part of their assessment and treatment. For adequate treatment of the woman with polycystic ovary syndrome, it biopsychosocial model should be used, with all aspects of the patient's mental status considered before implementation of optimal intervention. (Endocr Pract. 2009;15:475-482)

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

(2005). An Evidence-Based Systematic Review of Echinacea (E. angustifolia DC, E. pallida, E. purpurea) by the Natural Standard Research Collaboration. Journal of Herbal Pharmacotherapy: Vol. 5, No. 2, pp. 57-88.

Review Methodology: Systematic Aggregation, Analysis, and Review of the Literature.Search Strategy: To prepare each Natural Standard monograph, electronic searches are conducted in nine databases, including AMED, CANCERLIT, CINAHL, CISCOM, the Cochrane Library, EMBASE, HerbMed, International Pharmaceutical Abstracts, Medline, and NAPRALERT. Search terms include the common name(s), scientific name(s), and all listed synonyms for each topic. Hand searches are conducted of 20 additional journals (not indexed in common databases), and of bibliographies from 50 selected secondary references. No restrictions are placed on language or quality of publications. Researchers in the field of complementary and alternative medicine (CAM) are consulted for access to additional references or ongoing research.Selection Criteria: All literature is collected pertaining to efficacy in humans (regardless of study design, quality, or language), dosing, precautions, adverse effects, use in regnancy/lactation, interactions, alteration of laboratory says, and mechanism of action (in vitro, animal research, human data). Standardized inclusion/exclusion criteria are utilized for selection.Data Analysis: Data extraction and analysis are performed by health care professionals conducting clinical work and/or research at academic centers, using standardized instruments that pertain to each monograph section defining inclusion/exclusion criteria and analytic techniques, including validated measures of study quality). Data are verified by a second reviewer.Review Process: Blinded review of monographs is conducted by multidisciplinary research-clinical faculty at major academic centers with expertise in epidemiology and biostatistics, pharmacology, toxicology, complementary and alternative medicine (CAM) research, and clinical practice. In cases of editorial disagreement, a three-member panel of the Editorial Board addresses conflicts, and consults experts when applicable. Authors of studies are contacted when clarification is required.

An evidence-based systematic review including scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/ dynamics, interactions, adverse effects, toxicology, and dosing.

St. John’s wort is an herb commonly used in Europe for decades and more recently the topic of scientific investigation in this country. St. John’s wort has been found more effective than placebo and equally as effective as tricyclic antidepressants in the short-term management of mild-tomoderate depression. Comparisons to selective serotonin reuptake inhibitors have provided equivocal data. While it is generally well tolerated in clinical use, there is accumulating evidence of significant interactions with drugs. This evidence-based presentation of the literature includes a brief description of pharmacodynamics and clinical applications, followed by a systematic review of adverse effects, toxicity, and drug interactions.

Red clover, a legume resembling soy is used by man as a phytoestrogen. Other uses include asthma, pertussis, cancer and gout. The authors systematically review this herb in terms of pharmacology, efficacy, safety, side effects, standardization, dosing, toxicology as well as other parameters.

The proposed uses, dosing parameters, adverse effects, toxicology, interactions and mechanism of action of kava is systematically reviewed in monograph format.