Background and Aims:Although many serological markers associated with inflammatory bowel disease have been defined, the evidence that interacts with clinical results is limited. We aimed to evaluate the relevance of anti-pancreatic antibody, p-ANCA and ASCA in the differential diagnosis of inflammatory bowel disease and their correlation with disease activity. Materials and Methods:The presence of antipancreatic antibody, p-ANCA and ASCA was determined in indirect immunofluorescence assay of serum samples from 95 patients with inflammatory bowel disease (63 ulcerative colitis, 29 Crohn's disease, 3 indeterminate colitis) and 65 healthy controls. Results:Anti-pancreatic antibody was present in 6,9% (2/29) in Crohn's disease and 3,2% (2/63) in ulcerative colitis. Anti-pancreatic antibody was not detected in the indeterminate colitis and control groups. No statistical difference was found between ulcerative colitis and Crohn's disease in terms of anti-pancreatic antibody incidence. p-ANCA was detected in 46% (29/63) in ulcerative colitis, 13,8% (4/29) in Crohn's disease, 66,6% (2/3) in indeterminate colitis, and 4,6% (3/65) in the control group. pANCA was statistically higher in ulcerative colitis compared to Crohn's disease. ASCA was present in 34,5% (10/29) in Crohn's disease, 7,9% (5/63) in ulcerative colitis and 3,1% (2/65) in the control group. ASCA was not detected in the patients with indeterminate colitis. ASCA was statistically higher in Crohn's disease compared to ulcerative colitis. It was found that anti-pancreatic antibody, p-ANCA and ASCA were not associated with disease activity in inflammatory bowel disease. Conclusions:We may conclude that anti-pancreatic antibody can be associated with inflammatory bowel disease, but it is not sufficient by itself for the differential diagnosis of inflammatory bowel disease. ASCA and p-ANCA may be helpful tools in the differential diagnosis of inflammatory bowel disease, but more studies are warranted for antipancreatic antibody

Data regarding early atherosclerosis and inflammatory bowel disease are limited and conflicting results are present.

In this study, we investigated whether reticulated platelets (RP) would be useful markers in the evaluation of ulcerative colitis (UC) activity and also aimed to gain indirect information about the platelet kinetics.

Gastrointestinal sistem tumorleri arasinda ince barsak tumorlerine seyrek rastlanir. Duodenum tumorlerinden ampulla cevresi yerlesimliler daha yuksek, bulbus yerlesimli olanlar da oldukca dusuk bir insidense sahiptir. Gerek bulbus ve gerekse 2. kisim yerlesimli tumorlerde, endoskopik tedavi yontemleri giderek onem kazanmaktadir. Bu tedavi yontemlerinden en sik uygulananlar snare polipektomi ve saline ile endoskopik mukozal rezeksiyondur. Bu yazimizda klinigimizde rastladigimiz bulbus yerlesimli buyuk bir adenomanin endoskopik tedavisini bildiriyoruz.