A series of (4-chlorophenyl)-α-(1-methyl-1H-imidazol-5-yl)azoloquinolines and -quinazolines was prepared. These compounds displayed potent Farnesyl Protein Transferase inhibitory activity and tetrazolo[1,5-a]quinazolines are promising agents for oral in vivo inhibition.
isabelle noelle constance pilatte合作论文数1Eddy Freyne合作论文数1Yannick Ligny合作论文数1Pieter Van Remoortere合作论文数1Michel Janicot合作论文数1Meyer Christophe合作论文数1Mévellec Laurence合作论文数1Angibaud Patrick合作论文数1
Philippe Muller合作论文数Centre national de la recherche scientifique1Geert Mannens合作论文数1Bruno Roux合作论文数1Gerda Smets合作论文数Gerda SmetsNo picture of Gerda Smets available - click to provide one
No description available of Gerda Smets1Xavier Bourdrez合作论文数1David W. End合作论文数1Walter Wouters合作论文数1Jacky Van Dun合作论文数1Marc Venet合作论文数1Virginie Poncelet合作论文数1Patricia Lezouret合作论文数1
