You have accessJournal of UrologyDiscussed Poster, Saturday, May 20, 2006, 1:00 - 4:00 pm1 Apr 200638: Drinking Water Source and Cigarette Smoking in Transitional Cell Carcinoma of the Bladder Vincenzo Serretta, Vincenzo Altieri, Giuseppe Morgia, Rosalinda Allegro, Darvinio Melloni, Alessandra Di Lallo, Michele Pavone-Macaluso, Aniello Zito, Giuseppe Carrieri, Gianfranco Testa, Antonio Gallo, Antonino Galuffo, Mario Motta, Natale S. Simone, Carta Cammarata, Angelo Armenio, Francesco Paolo Selvaggi, Domenico Lo Presti, Gstu Foundation, and Members Of Gruppo Studi Tumori Urologici (Gstu) Foundation Vincenzo SerrettaVincenzo Serretta More articles by this author , Vincenzo AltieriVincenzo Altieri More articles by this author , Giuseppe MorgiaGiuseppe Morgia More articles by this author , Rosalinda AllegroRosalinda Allegro More articles by this author , Darvinio MelloniDarvinio Melloni More articles by this author , Alessandra Di LalloAlessandra Di Lallo More articles by this author , Michele Pavone-MacalusoMichele Pavone-Macaluso More articles by this author , Aniello ZitoAniello Zito More articles by this author , Giuseppe CarrieriGiuseppe Carrieri More articles by this author , Gianfranco TestaGianfranco Testa More articles by this author , Antonio GalloAntonio Gallo More articles by this author , Antonino GaluffoAntonino Galuffo More articles by this author , Mario MottaMario Motta More articles by this author , Natale S. SimoneNatale S. Simone More articles by this author , Carta CammarataCarta Cammarata More articles by this author , Angelo ArmenioAngelo Armenio More articles by this author , Francesco Paolo SelvaggiFrancesco Paolo Selvaggi More articles by this author , Domenico Lo PrestiDomenico Lo Presti More articles by this author , Gstu Foundation More articles by this author , and Members Of Gruppo Studi Tumori Urologici (Gstu) Foundation More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32305-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "38: Drinking Water Source and Cigarette Smoking in Transitional Cell Carcinoma of the Bladder." The Journal of Urology, 175(4S), pp. 13–14 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 13-14 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Vincenzo Serretta More articles by this author Vincenzo Altieri More articles by this author Giuseppe Morgia More articles by this author Rosalinda Allegro More articles by this author Darvinio Melloni More articles by this author Alessandra Di Lallo More articles by this author Michele Pavone-Macaluso More articles by this author Aniello Zito More articles by this author Giuseppe Carrieri More articles by this author Gianfranco Testa More articles by this author Antonio Gallo More articles by this author Antonino Galuffo More articles by this author Mario Motta More articles by this author Natale S. Simone More articles by this author Carta Cammarata More articles by this author Angelo Armenio More articles by this author Francesco Paolo Selvaggi More articles by this author Domenico Lo Presti More articles by this author Gstu Foundation More articles by this author Members Of Gruppo Studi Tumori Urologici (Gstu) Foundation More articles by this author Expand All Advertisement PDF downloadLoading ...

As a preliminary approach to define the object of larger case-control studies, the distribution of potential risk factors coming from environmental pollution among patients affected by superficial bladder cancer (TCCB) has been analyzed. Material e Methods. The analysis included only patients affected by medium risk superficial TCCB. Forty Italian urological centres joined the study. Detailed information about age, sex, residency, employment, active and passive cigarette smoking, water resource, hair-dye use were centralized. All patients underwent TUR and early intravesical chemotherapy. The distribution of the above mentioned environmental factors was related to tumor characteristics such as multiplicity and previous natural history. Results. Until today 474 patients have been recruited, 182 (38.4%) with primary tumors and 293 (61.8%) with multiple lesions. Over 80% of the patients lived in urban areas, 20% were employed in industry at risk for bladder cancer and 8% used hair dye. Forty percent of the patients were smokers, with a median smoking period of 30 years. Bottled water was the only water resource in 42% of cases. At multivariate statistical analysis a significant correlation between tumor multiplicity and employment in industry (p<0.01) and between past natural history and period of cigarette smoking (p<0.05) was found. Preliminar/y, an interesting trend was detected for a correlation between water resource and bladder cancer in non-smoking patients. The municipal water system was the main water resource more frequently in non-smokers (75% vs 53%). This might imply a pathogenic role of water pollution and chlorination.

Esso puo essere distinto dal punto di vista etiopatogenetico in: A) idiopatico: causa predisponente una difettosa struttura della parete venosa che si associa molto spesso a varici degli arti inferiori e a varicosita del plesso emorroidale; B) sintomatico: come conseguenza di una compressione della vena spermatica'v legata a varie affezioni quali tumori renaIi, idronefrosi giganti ecc. II varicocele Idiopaticov" epresente nel 10·20% della popolazione maschile e nel 40% degli uomini infertili; in genere si manifesta a sinistra nel 90% dei casi, ebilaterale nell'8% ed ea carico del distretto di destra solo nel2% dei pazienti. Sappiamo, dagli studi pill recenti, che tale patologia si accompagna, nel 60% dei casi, alIa produzione di un Iiquido seminale di qualita scadente.I!' e questa percentuale appare strettamente correlata alla sterilita maschile. E inoltre direttamente proporzionale al tempo; infatti, nel giovane, quanto piu lungo eil tempo che intercorre tra diagnosi e terapia chirurgica del varicocele, tanto maggiori sono le probabilita di insuccesso terapeutico e di conseguente infertilita.