Background: The female genital tract is rarely involved by metastatic tumors. The most common anatomic locations for metastases to the female genital tract are the ovaries and the vagina. Among extragenital cancers metastasizing to the female genital tract, breast is the most common primary site, followed by the gastrointestinal tract, lung, kidney, and skin melanoma. Metastases to the uterus from extragenital cancer are less common, but up to 8% of breast carcinomas will metastasize to that organ. Lobular carcinoma is the most common type of breast carcinoma that metastasizes to the uterus. In our case, we present a case of concurrent metastatic breast carcinoma to the uterine cervix.
Introduction: Breast cancer, the first cause of cancer-related death in women, is a heterogeneous disease, with different subtypes depending on the expression of endocrine receptors. Triple Negative Breast Cancer (TNBC) has worse prognosis with an aggressive clinical course and high recurrence rates. Depending on the luminal androgen receptor (LAR) expression, TNBC has two subtypes: the classic phenotype-LAR and the Quadruple Negative Breast Cancer (QNBC). This study aims to compare overall survival (OS) and Disease-Free Survival (DFS) between these two phenotypes.
Colovaginal and colo-ovarian fistulas are rare entities that could be attributed to diverticular disease after an episode of acute diverticulitis. Τhey could initially be manifested with symptoms that lead patients to the gynecologist. Gynecologists should consider them in the differential diagnosis, especially after recurrent episodes of sinusitis. We report the case of a 51-year-old woman with a colovaginal and a colo-ovarian fistula due to subclinical diverticular disease, which should be involved in the differential diagnosis in those complicated fistulas, even if the patient had never before a clinical episode of acute diverticulitis or known diverticular disease, and a successful surgical approach.