TiO2-PTFE compound coating was prepared on the surface of TC4 titanium alloy by the special chemical and physical method.The lubricant film was composed of hard anodic oxidation film and PTFE with low friction factor,which had excellent self-lubricant property.Microstructure and morphology,phase composition and element composition of TiO2-PTFE compound coating were investigated.The effect of anodic oxidation treatment process and coating time on the coating volume of PTFE was discussed.Results of the experiment showed that after anodic oxidation,the nanometer TiO2 porous film was consisted of annatase and rutile phases formed on TC4 titanium alloy.After being coated with PTFE,the surface and film hole were covered by PTFE polymer.The PTFE coating volume kept stable after the samples of TC4 titanium alloy being treated in different voltages and different oxidation time.As the coating time prolonging,the PTFE coating volume increased rapidly in the first 5-20min,the coating volume increased slowly after more than 20min.