Objective:Mechanical ventilation for respiratory medical factors in patients with nosocomial infection were analyzed. Methods:Chooses the patient 70 examples which my courtyard internal medicine department infects to divide into 2 groups stochastically,the control group 35 examples adopts the non-machinery to pass machine,the observation group 35 examples adopt the machinery ventilation,the contrastive analysis and study its nosocomial infection the characteristic..Results:The patients displayed the results of bacterial isolates,132 strains were isolated,including 107 for the G-strain,23 strains of G + bacteria.Control group patients showed the results of bacterial isolates, 90 strains were isolated,of which 72 for the G-strain,18 were G + strain.The distribution of the two groups for the bacteria,pathogens in the observation group was Acinetobacter baumannii,Pseudomonas aeruginosa,Klebsiella pneumoniae,Staphylococcus aureus,the control group bacteria Acinetobacter baumannii group,Haemophilus influenzae,Staphylococcus aureus,Pseudomonas aeruginosa,Klebsiella pneumoniae. Comparison with results on the different time segments of different strains appear in the observation group the number of lower respiratory tract was significantly higher disease-causing bacteria..Conclusion:Easy to cause respiratory infection in hospital medical patients include mechanical ventilation,disinfection and isolation take the appropriate measures to strengthen the ward management,improve the overall intensity of nursing interventions,can reduce the incidence of hospital infections and improve the quality of life of patients..