Objective To explore the factors associated with the complications of cranioplasty, infection and local epidural hematoma, such as age, sex, primary disease, skull defect and concomitant hydrocephalus. Methods 211 patients after cranioplasty were reviewed. Re-sults 8 cases (3.8%) complicated one of them, in which 6 cases with local epidural hematoma and 2 cases with infection. The infection was more likely related with the areas of skull defect (P=0.003). No factor was found related with the local epidural hematoma. Conclusion It is necessary to focus the size of the frontal sinus when repairing the the frontal bone, to avoid the screw into the frontal sinus caused infection.

抗癌药物在进行动物和临床试验以前,需要用体外肿瘤组织模型评估药效.由于三维(3D)多细胞球体(multicellular tumor spheroids MCTSs)在抗药性和组织结构等方面与体内肿瘤组织相似,常被用作体外肿瘤组织模型.为监测MCTSs在形成过程中,肿瘤细胞之间和肿瘤细胞与基质之间的相互作用,基于微流控技术基础上自行设计和构建MCTSs模型.该肿瘤MCTSs模型实验结果表明,在3D微环境下,血清能够诱导MDA-MB-231形成直径为289 μm的MCTSs,肿瘤细胞MCTSs之间有相互靠近的趋势,并且发现凋亡细胞多分布在MCTSs之间.肿瘤坏死因子(tumor necrosis factor.-α,TNF-α)诱导MDA-MB-231形成MCTSs之间没有相互靠近的趋势,并且MCTSs直径的长度很难达到100 μm.以上结果表明,该模型有望为研究肿瘤形成MCTSs机制和药物筛选提供有用的体外肿瘤模型.

A system utilizing LNG cold energy to generate power output was proposed. This system is combined with a LNG power generation cycle and a thermoelectric generator (TEG), which is also a heat exchanger at the same time. The performance of the system has been analyzed and calculated for different methane concentrations in LNG. The calculation results showed that the energy efficiency of this power generation system is up to 29%.