Although insular infiltration by gliomas is relatively common, the related symptomatology is poorly known and therefore often undiagnosed. To better diagnose insular signs with a new designed questionnaire: the QuID -7. The QuID 7 covers 7 semiological fields corresponding to 27 items related to insular symptomatology, based on the literature data. Over a 13 month period, patients with a histological diagnosis of cerebral glioblastoma were reviewed. Those with a bifocal lesion, aphasic disorders or altered general state, were excluded. Questionnaires were administered at the same time point during the patients’ follow-up, corresponding to the first monthly cure of temozolomide. 44 patients were included, 30 of them (68%) with insular involvement. None of the patients refused the questionnaire. Administration time was about 10 minutes. Insular patients reported overall more signs than the non-insular group (75% versus 25 %) and in each semiological field: somato-sensorial (75 % vs 25%), viscero-sensorial (64% vs 36%), auditory (83% vs 17%), gustatory (76% vs 24%), language (81% vs 19%), neuropsychiatric (72% vs 28%). The most pathognomonic sign of insula involvement was the presence of symptoms ipsilateral to the lesion side, particularly for the somatosensory (7%) and auditory (44%) fields. The QuID 7 was well accepted and easily understood by all patients. QuID 7 brings a new visibility to the insular symptomatology for physicians in their medical practice. Moreover, our results point out (i) the importance of sensorial manifestation, and (ii) that symptoms related to an insular lesion can be ipsilateral to the lesion side.