A cacalolide derivative named 4α-[2′-hydroxymethylacryloxy]-1β-hydroxy-14-(5→6) abeo eremophilan-12,8-olide and a shikimic acid derivative named (3′E)-(1α)-3-hydroxymethyl-4β,5α-dimethoxycyclohex-2-enyloctadec-3′-enoate along with three known compounds, octacosan-1-ol, 3β-hydroxyolean-12-en-28-oic acid and 3β-acetoxyolean-12-en-28-oic acid were isolated from Senecio burtonii. Their structures and relative configurations were established on the basis of spectroscopic analysis.
In addition to one known compound, 3 beta, 8 alpha-dihydroxyguaian- 4(15), 10(14), 11(13)- trien-6,12 olide (8-desacylcynaropicrin) ( 3), two new sesquiterpene lactones have been isolated from the aerial parts of Crepis cameroonica. By means of spectroscopic analysis, the structures and relative configurations of the new compounds were established as 3 beta, 9 beta-dihydroxyguaian4( 15), 10( 14), 11( 13)- trien-6,12 olide ( 1) and 8 alpha-hydroxy-4 alpha( 13), 11 beta(15)-tetrahydrozaluzanin C (2). The in vitro antimicrobial spectrum of pure compounds and crude extracts are also reported.
From the methanol extract of the stem bark of Scaphopetalum thonneri, two new compounds, including one lignan, named scaphopetalone, one new ester of ferulic acid, named scaphopetalumate were isolated together with three known compounds including: two coumarins (scopoletin and scopolin), and one pentacyclic triterpene (oleanolic acid). The structure of the new compounds were elucidated by means of spectroscopic analyses.
One new diterpenoid, methyl 3α-hydroxy-7-oxo-dehydroabietate (1), two new limonoids, 3α-deacetyl-amoorastatin (2) and 9β-amoorastatin (3), and the known limonoid amoorastatin (4) were isolated from the stem of Pterorhachis zenkeri.