A pulmonologic healthcare system was organized at the Altai region including a regional pulmonology center, pulmonology department of city hospitals, referable pulmonology wards and asthma-schools working as outpatient departments for asthmatic patients. A new structure of a regional pulmonology center was created which involves an intensive care unit for pulmonary pathology and respiratory support and a regional asthmacenter with ambulatory working mode providing oxygen therapy at home. Due to this, early-stage detection of respiratory pathologies was improved, a number of admissions to hospitals was reduced for certain diseases and a mortality of severe lung pathologies was decreased.
Complex treatment of acute abscesses and gangrene of the lungs, including intensive therapy and resuscitation, nonoperative treatment with the use of methods for releasing microcirculation from blocking, inhibition of proteolysis in the focus, differentiated correction of the functional activity of phagocytes in the focus of affection, etc., is conducive to reduction of the frequency of the development of a chronic process and drop of mortality.
With an adjuvant course of plasmapheresis, a combined treatment of severe acute abscesses and gangrene of the lungs brought about a marked short-term clinical response in 48 out of 50 treated patients. The responders had their temperature returned to normal, amount of sputum significantly reduced. They recovered good appetite and gained weight. There was also attenuation of DIC syndrome and endotheliosis, improvement of cellular and humoral immunity. Upon the discharge 35 patients had complete or partial response, 10 patients developed a chronic process. Lethal outcomes reached 10%.