Objective To observe the protective effects of "Xiusanzhen" on the learning and memory of patients with Alzheimer's disease.Methods 60 cases of Alzheimer's disease were treated with "Xiusanzhen".Hasegawa s Dementia scale(HDS),Mini-mental State Examination(MMSE) and FAQ were evaluated before and after treatment.Results After the treatment with "Xiusanzhen",12 cases were markedly effective,36 cases effective and 12 cases invalid.The effective rate was 80 %.Conclusions "Xiusanzhen" can improve the dysfunction of learning and memory on patients with Alzheimer's disease.

目的探讨嗅三针对血管性痴呆大鼠学习记忆功能及血浆β-内啡肽含量的影响作用。方法取SD大鼠。随机分为正常对照组、VD模型组、嗅三针组,每组10只。制作VD大鼠模型,通过嗅三针电刺激方法,测试大鼠水迷宫学习记忆能力并测定血浆β-内啡肽含量。结果定位航行试验显示,平均逃避潜伏期和平均游泳路程比较,正常对照组明显短于VD模型组(P<0.01);嗅三针组明显短于VD模型组(P<0.01);血浆β-内啡肽含量比较,VD模型组低于正常对照组(P<0.05);嗅三针组高于VD模型组(P<0.05)。结论嗅三针能够显著增强血管性痴呆大鼠学习记忆功能、并且同时提高了血浆β-内啡肽的含量。