目的:了解宁波某企业体检人群中甲状腺结节检出率,并分析相关影响因素.方法:收集宁波某大型国有企业5416名体检人员的体检资料.将人群分为甲状腺结节组与非甲状腺结节组,组间比较根据数据类型分别用两独立样本t检验、χ2检验进行分析,并用多因素Logistic回归分析受检人群中甲状腺结节检出率的影响因素.结果:甲状腺结节总检出率为35.8％,其中女性为48.4％,男性为32.6％;不同年龄段女性检出率均高于男性,且甲状腺结节检出率随年龄增长而显著升高(P<0.05).多因素Logistic回归分析显示,性别、年龄和腰围是甲状腺结节的可能影响因素(P<0.05).结论:宁波某企业体检人群中女性甲状腺结节检出率明显高于男性,性别、年龄和腰围与甲状腺结节有显著相关性.

OBJECTIVE:To study the correlation between non-alcoholic fatty liver disease (NAFLD) and glycosylated hemoglobin (HbA1c) in middle-aged and aged population.METHODS:A total of 4 127 in-service workers and retirees aged 45 years old or above from one petrochemical enterprise in Ningbo were enrolled in our study. The waistline, body mass index, blood pressure, fasting blood-glucose, blood lipid profile, glutamyltranspeptidase, HbA1c and epigastrium B ultrasound were investigated. According to the quartile of HbA1c level, participants were divided into four groups, namely, Q1 group ≤5.2%, Q2 group >5.2%-5.4%, Q3>5.4%-5.6% and Q4 group>5.6%. The prevalence of NAFLD and clinical characteristics of each group were analyzed. Logistic regression was used to predict independent risk factors of NAFLD.RESULTS:The morbidity of NAFLD was 27.2% with 31.9% in male and 21% in female, which was significantly higher in men. In Q1, Q2, Q3 and Q4 group, the prevalence of NAFLD were 18.5% (178/961), 22.8% (185/812), 25.6% (280/1 095), 38.1% (480/1 259) respectively. With the increase of HbA1c level, the morbidity of NAFLD increased synchronously. The age, systolic pressure, total cholesterol, low density lipoprotein cholesterin and fasting blood-glucose were all elevated according to the increase of HbA1c in 1 123 NAFLD patients. Multi-factor logistic regression analysis indicated that high HbAlc level was the risk factor of NAFLD (OR=1.67, 95%CI 1.15-2.43, P=0.007).CONCLUSION:HbA1c is an independent risk factor of NAFLD and both of these are closely related to blood lipid metabolism disorder.