腹泻型肠易激综合征(IBS-D)是临床上常见的一种缺乏胃肠道结构改变的功能性肠病,在临床中本病多从脏腑及病理因素进行辨证论治.经络不仅是气血运行的通道,而且在内归属于脏腑,与脏腑的联系相当密切.本文拟从经络理论、经络与脏腑间的相互联系及经络系统循行探析IBS-D的病因病机、主要临床表现,阐述在IBS-D治疗中以经络辨证为基础,并根据获得的临床讯息进行分经辨证、分经选方、分经选穴,针药并用,希望能从经络辨证角度拓展IBS-D的中医治疗思路.

Recently, the albumin-to-globulin ratio (AGR) has been investigated as a prognostic parameter in patients with colorectal cancer (CRC); however, the results remain inconsistent. We aimed to quantitatively identify the prognostic role of the AGR in CRC through meta-analysis. Combined hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated to assess the prognostic value of the AGR for overall survival (OS), disease-free survival (DFS)/progression-free survival (PFS), and cancer-specific survival (CSS). The association between the AGR and clinicopathological factors was investigated using pooled odds ratios (ORs) and 95% CIs. Eleven studies, comprising 8,397 patients, were included in this meta-analysis. Our results demonstrated that a low AGR was significantly associated with poor OS (HR, 2.58; 95% CI, 1.90-3.51; p < 0.001) and poor DFS/PFS (HR, 2.11; 95% CI, 1.46-3.05; p < 0.001) in CRC. However, the AGR was not a significant prognostic factor for CSS (HR, 1.008; 95% CI, 0.372-2.730; p = 0.988). In addition, a low AGR was associated with patients aged >= 60 years (OR, 1.71; 95% CI, 1.54-1.89; p < 0.001). A low AGR was significantly associated with worse OS and inferior DFS/PFS in patients with CRC. Thus, AGR can be used as a cost-effective and reliable prognostic marker for CRC in clinical practice.

Irritable bowel syndrome (IBS) is a gastrointestinal disorder with no structural damage and biochemical abnormality, and its pathogenic mechanism is still unclear. Variety of drugs, psychotherapy, diet regulation and other methods have been used by modern medicine to relieve symptoms, but the effect is not satisfactory. In recent years, TCM treatment of IBS has attracted widespread attention, especially for constipation type and diarrhea type. Among the many experiments, most of the traditional Chinese medicine experiments aimed at the 5-HT signaling pathway have achieved good results. Therefore, this paper summarizes the main mechanisms and results of traditional Chinese medicine based on 5-HT in the treatment of IBS, in order to provide a reference for subsequent research.

肛周感染是血液系统疾病患者常见并发症之一,临床中常予以抗生素治疗、对症治疗及局部处理.在接受手术的患者中,术后常沿用保守治疗的方案,收效欠佳,手术切口愈合不良或延迟愈合.中国中医科学院西苑医院肛肠科在长期的临床实践中,对血液系统疾病合并肛周感染的手术患者予以中西医结合治疗方案,在术后抗感染治疗、常规换药护理、外用抗生素保留灌肠的基础上,加用中医内治及外治并进的治疗方法,收到了良好的短期效果.