目的:探讨微创腔镜手术治疗ⅠA2~ⅡA期宫颈癌的临床疗效.方法:选择2015年12月至2016年12月我院行手术治疗的88例ⅠA2~ⅡA期宫颈癌患者作为研究对象,随机分为对照组(行开放式全子宫切除术+腹盆腔淋巴结清扫术)与观察组(行微创腔镜广泛全子宫切除术+盆腔淋巴结清扫术),每组44例.评价两组患者的术中情况与术后指标、术后并发症情况以及1年内宫颈癌的复发率.结果:观察组手术时间、术中失血量,术后尿管拔除时间、恢复排气时间、住院时间均低于对照组(P<0.05);两组淋巴结清除个数、宫颈阴道旁组织切缘与肿瘤病灶的距离差异无统计学意义(P>0.05).观察组术后并发症低于对照组(P<0.05).观察组患者1年内复发率与对照组差异无统计学意义(P>0.05).结论:微创腔镜手术治疗ⅠA2~ⅡA期宫颈癌临床疗效确切,具有术中操作快速、失血量少、术后并发症低、利于术后恢复等优势,适于临床推广.

目的 探讨慢性宫颈炎患者的发病原因及相关的危险因素.方法 选取2015年1月-2016年1月在广东省深圳市妇幼保健院进行治疗的慢性宫颈炎患者100例,以及同一时期在该院进行健康体检的健康妇女120例作为研究对象,慢性宫颈炎患者作为病例组,健康体检的健康妇女作为对照组.对两组患者进行问卷调查,调查内容主要包括:受教育程度、人工流产次数、年龄、初次性生活年龄、性伴侣数、初次妊娠年龄、避孕方式等.采用病例对照研究进行慢性宫颈炎发病原因分析,多因素Logistic回归分析进行慢性宫颈炎相关危险因素分析.结果 单因素分析显示,病例组人工流产次数≥3次、初次性生活年龄＜18岁、性伴侣≥2个、配偶包皮过长等比例高于对照组,差异有统计学意义(P＜0.05).Logistic回归分析结果显示,人工流产次数≥3次、初次性生活年龄＜18岁、性伴侣≥2个、配偶包皮过长等是慢性宫颈炎发病的危险因素(P＜0.05).结论 为预防慢性宫颈炎的发生,应加强生殖保健卫生知识宣教,女性避免过早性生活、婚前妊娠.

Objective To investigate the plasma D-dimer level in different pregnancy and early puerperal women and its significance.Methods From January 2013 to December 2015, 1 534 cases of pregnancy women were selected, and divided into four groups according to pregnancy weeks.Early pregnancy group: 360 cases within 12 weeks of pregnancy;Mid pregnancy group: 454 cases with 12-28 weeks of pregnancy;Late pregnancy group: 362 cases over 28 weeks of pregnancy;Puerperium group: 358 cases of delivery to postpartum 96 h.one humdred and sixty-eight cases of normal medical women at the same time were selected as the non-pregnancy group.plasma D-dimer levels in women was compared among the five groups, and venous thromboembolic disease (VTE) plasma D-dimer levels in women was analyzed.Results The difference of plasma D-dimer level between the early pregnancy group and non-pregnancy group was not significant (P<0.05).Plasma D-dimer levels of the early pregnancy group, late pregnancy group and puerperium group were higher than that of the non-pregnancy group, the differences were significant (P<0.05).VTE occurred rate was 0.13% (2/1 534), venous thrombosis in lower limbs was 2 cases, underwent the cesarean section, and were diagnosed by ultrasound, venous angiography.Serum D-dimer level in late pregnancy was 164.15, 156.91 mg/L, which were positive.Conclusion With the development of pregnancy, the level of plasma D-dimer levels in creased gradually.That is not recommended for routine screening of plasma D-dimer levels to exclude the occurrence of VTE, it should be combined with B ultrasound and other means for screening of VTE in VTE pregnant women without clinical manifestations.

目的 对比盆底重建术与传统手术方案应用于盆腔器官脱垂(POP)治疗中的效果.方法 选择2014年8月-2016年8月该院收治的POP患者62例,采用随机数字表将其分为两组,即对照组与研究组各31例.对照组行传统阴式子宫全切术联合阴道后壁修补术治疗,研究组行盆底重建术.观察对比两组手术时间、出血量、住院时间、临床治疗效果及术后并发症情况.结果 研究组手术时间、出血量、住院时间均低于对照组(P＜0.05).研究组治疗总有效率96.77％,高于对照组的74.19％(P＜0.05).研究组术后并发症发生率为6.45％,与对照组的9.68％对比差异无统计学意义(P＞0.05).结论 相较于传统手术方案,盆底重建术应用于POP患者中具有更为显著的治疗效果,适于临床推广.