Objective To investigate the effect of nontreponemal antibodies on HIV gelation particle agglutination test in syphilis cases.Methods The nontreponemal antibodies,treponemal antibody and HIV antibody in serum samples from 96 syphilis patients and 96 healthy controls were tested with rapid plasma reagent circle card test(RPR),treponema pallidum particle assay(TPPA),HIV gelatin particle agglutination test(HIV1/2-PA) and Determine HIV-1/2 test.Results In 96 syphilis serum samples,32 samples showed agglutination pictures in both sensitive and unsensitive particles HIV1/2-PA test and so the results were undeterminable.These 96 syphilis serum samples were divided into 11 groups according to nontreponemal antibodies titers(RPR titers),which showed that interfering results of HIV1/2-PA occurred more frequently with RPR titer rising.The undeterminable results occurred with a significant difference between the group with RPR titers up 1∶8(1∶8)and the group with RPR titers down 1∶8(≤1∶8)(χ2=74.73 P0.005).Nine cases with undeterminable HIV1/2-PA results were followed up.They were tested with HIV1/2-PA in 6 months after the treatment with benzathine penicillin.The follow up results showed that the phenomenon of agglutinating unsensitive and sensitive particles disappeared and their HIV antibodies all were negative.On the other hand,their RPR titers all dropped down to 1∶8(≤1∶8)and there were 4 cases where the treponemal antibody titers rose and 4 cases where the antibody remained unchanged.The phenomenon of agglutinating unsensitive and sensitive particles did not appear in 5 samples,which were positive in RPR and negative in TPPA,but their RPR titers were all under 1∶8.Conclusions High titers of nontreponemal antibodies(1∶8)in serum samples were essential to interfering HIV1/2-PA results.

Objective Through voluntary counseling and testing(VCT) for AIDS to earlier identify HIV carriers and provide them with timely treatment and appropriate interventions so as to reduce risk of infection and prevent spread of AIDS.Methods Standardized VCT service for AIDS was provided to the visitors by setting up counseling rooms in STD out patient clinics.Results In the past year,1921 visitors received VCT service and 6 of them were identified as HIV positive.Compared to the HIV prenalence rate in the general population(0.005%),the high HIV detecting rate in the present study(0.31%) had statistical significance by u test(P0.0005).Conclusion This study have demonstrated that implementation of VCT for AIDS in STD out patient clinics is an effective way to identify HIV positive persons,which can attract the high-risk individuals to receive counseling and detection for AIDS.

为了解南京地区支原体的耐药情况,准确地指导用药,我们选择在泌尿生殖道感染中起重要作用的解脲支原体(Uu)作为检测对象,使用法国生物-梅里埃的IST2试剂盒,对从性病门诊患者中分离的97株Uu进行了抗菌药物耐药性测定,现将结果报告如下.