Objective To evaluate the correlation between helicobacter pylori (HP) infection and patients with long-term hemodialysis and the effect of dialysis time to the HP infection. Methods Totally 169 patients with hemodialysis were enrolled in the hemodialysis group, and 125 healthy people people who had physical examination at the same time served as the control group. The HP was detected by 14C-urea breath test, and the endoscopy was performed on patients with gastrointestinal symptom in the two group before hemodialysis. The HP test also applied to patients in the hemodialysis group at the beginning, 2-year and 5-year after hemodialysis. Results Before the hemodialysis, the rates of HP infection between the two groups showed no significant differences (χ2=0.050, P=0.815), and 179 patients (82 cases in the control group, 97 cases in the hemodialysis group) were underwent endoscopy. The incidence of gastritis in the control group was lower (χ2=9.220, P<0.05), and the prevalence of gastric ulcer and duodenal ulcer were higher than those in the hemodialysis group ( χ2=5.024, 3.211, all P<0.05). As a result of death, peritoneal dialysis, renal transplantation or transfer, only 148 patients in the hemodialysis group were accomplish the HP test at different time points. The rates of HP infection were 69.6% (103/148), 54.7% (81/148) and 45.3% (67/148), respectively, and the infection rates decreased gradually with the time of hemodialysis ( χ2=18.111, P<0.001). Conclusion Long-term hemodialysis patients have a lower HP infection rate and the HP infection rate gradually decreased along with the treatment.

<正>过敏性紫癜性肾炎(schonlein-henoch purpura nephritis,HSPN)是由于过敏性紫癜(HSP)而导致的肾损害,是一种以坏死性小血管炎为基本病变的免疫性疾病,临床以皮肤紫癜、出血性胃肠炎、关节炎及肾脏损害为特征。近年来文献报道[1,2]幽门螺杆菌(helicobacterpylori,Hp)感染后的免疫反应可能与

<正>可逆性后部白质脑病综合征(reversible posterior leukoen-cephalopathy syndrome,RPLS)是一种以可逆性神经精神障碍及影像学改变为特征的罕见综合征。该综合征首先由Hinchey报道[1],临床表现以急性起病、

从1960年最初提出连续性血液净化治疗的概念[1]及1977年Kramer等[2]率先报道使用连续性动静脉血液滤过(CAVH)抢救急性肾衰竭至今,连续性肾替代治疗(CRRT)近年来更是得到跨学科的广泛应用和发展.