Histone H3.3 (H3F3A) mutation in the codon for lysine 27 (K27M) has been found as driver mutations in pediatric glioblastoma and has been suggested to play critical roles in the pathogenesis of thalamic gliomas and diffuse intrinsic pontine gliomas. We report a case of thalamic glioma with H3F3A K27M mutation, which was detected in both the primary tumor diagnosed as diffuse astrocytoma obtained during the first surgery and also in the tumor diagnosed as anaplastic astrocytoma obtained at the second surgery.
Yoshiyasu Iwai合作论文数Department of Neurosurgery, Osaka City General Hospital2
Jyunichi Hara合作论文数1
Kenichi Ishibashi合作论文数1Masaki Yoshimura合作论文数1Hiroko Fukushima合作论文数1Hiroaki Sakamoto合作论文数1Yoshioka Ema合作论文数1Nakajo Kosuke合作论文数1
Kai Yamasaki合作论文数1Inoue Takeshi合作论文数1Kazuhiro Yamanaka合作论文数1Tomoko Shofuda合作论文数1Yonehiro Kanemura合作论文数1
