Radix Angelicae Sinensis, known as Danggui in China, is an effective and wide applied material in Traditional Chinese Medicine (TCM) and it is used in more than 80 composite formulae. Danggui from Minxian County, Gansu Province is the best in quality. To rapidly and nondestructively discriminate Danggui from the authentic region of origin from that from an unauthentic region, an electronic nose coupled with multivariate statistical analyses was developed. Two different feature extraction methods were used to ensure the authentic region and unauthentic region of Danggui origin could be discriminated. One feature extraction method is to capture the average value of the maximum response of the electronic nose sensors (feature extraction method 1). The other one is to combine the maximum response of the sensors with their inter-ratios (feature extraction method 2). Multivariate statistical analyses, including principal component analysis (PCA), soft independent modeling of class analogy (SIMCA), and hierarchical clustering analysis (HCA) were employed. Nineteen samples were analyzed by PCA, SIMCA and HCA. Then the remaining samples (GZM1, SH) were projected onto the SIMCA model to validate the models. The results indicated that, in the use of feature extraction method 2, Danggui from Yunnan Province and Danggui from Gansu Province could be successfully discriminated using the electronic nose coupled with PCA, SIMCA and HCA, which suggested that the electronic-nose system could be used as a simple and rapid technique for the discrimination of Danggui between authentic and unauthentic region of origin.

总结了药典2010年版一部毒性中药品种,并对其炮制方法进行了述要.

通过检索20多年来有关柴胡研究的文献报道,发现包括发展人工资源有关的资源调查、中药鉴别、组织培养、栽培技术占药用柴胡文献较多,以质量评价及药效学基础的化学成分研究发展也较快,分子生药学研究成为20年来柴胡研究的新趋势,从中可以看出中药鉴定研究的某些规律和趋势.

用极性不同的溶剂对藏药翼首草的根进行提取,分别对溶剂提取物与提取后的药材残渣测定红外光谱,并进行比较。结果表明极性不同的溶剂各提取物与各药材残渣之间的光谱差别较大,红外光谱既可快速鉴别药材质量(有效成分是否已被提取),也可为初步的化学提取提供指导。

目的研究藏药翼首草的抗炎作用,并进行急毒实验.方法抗炎作用研究采用大鼠急性足肿胀实验、小鼠棉球肉芽肿实验、小鼠急性耳肿胀实验和小鼠急性渗出实验等方法.结果翼首草能显著地抑制炎症的产生;且毒性不大.结论翼首草皂苷具有较强的抗炎作用,无明显毒性.

OBJECTIVETo study the identification method of Pterocephalus hookeri.METHODThe microscopical, Physicochemical and TLC methods were used.RESULT AND CONCLUSIONThe convenient and effective identification methods for P. hookeri were established, which provide basis for its quality standard and development.