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个人简介
My research focus in the metabolomics research is at the comprehensive analysis of all metabolites in a studied biological system that can describe metabolic changes caused by disease, environmental, nutritional, or genetic factors in an organism. For this, the goal in my research has been the development of efficient, high-throughput methodologies for profiling of the biological samples, based on both more conventional chromatographic methods as well as in comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry, ultra high performance liquid chromatography combined with various mass spectrometers. We have been developing both non-targeted profiling methods in discovery studies, as well as for targeted analysis of specific compounds, with the goal for as comprehensive coverage of the metabolome as possible. Here, the major goal is the development of more reliable and sensitive methodologies, particularly for comprehensive profiling of complex samples. Identification of unknown compounds with the mass spectrometric tools is the main challenge in the research. For this, development of software tools for the treatment of MS data has been a key issue as manual identification of hundreds or even thousands of unknown compounds in large sample series is not a viable option.
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论文共 322 篇作者统计合作学者相似作者
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Tuulia Hyotylainen,Aidan Mcglinchey,Samira Salihovic, Antonia Schubert,Alex Douglas,David C. Hay, Peter J. O'Shaughnessy,John P. Iredale,Sophie Shaw,Paul A. Fowler,Matej Oresic
SCIENCE OF THE TOTAL ENVIRONMENT (2024): 167307-167307
Partho Sen,Yong Fan,Jennifer J. Schlezinger, Stanislav D. Ehrlich, Thomas F. Webster,Tuulia Hyötyläinen, Oluf Pedersen,Matej Orešič
Environment International (2024): 108569-108569
Jakob Karlsson,Patricia Lopez-Sanchez,Tatiana Milena Marques,Tuulia Hyotylainen,Victor Castro-Alves, Annika Krona,Anna Strom
FOOD HYDROCOLLOIDS (2024): 109306-109306
Angelica P. Ahrens,Tuulia Hyötyläinen,Joseph R. Petrone, Kajsa Igelström, Christian D. George,Timothy J. Garrett,Matej Orešič,Eric W. Triplett,Johnny Ludvigsson
Cellno. 8 (2024): 1853-1873.e15
FOOD HYDROCOLLOIDS (2024): 109732
Tito Damiani,Steffen Heuckeroth,Aleksandr Smirnov, Olena Mokshyna,Corinna Brungs,Ansgar Korf,Joshua Smith,Paolo Stincone, Nicola Dreolin,Louis-Félix Nothias,Tuulia Hyötyläinen,Matej Orešič,
crossref(2024)
Mika Hilvo,Carsten Denkert,Laura Lehtinen, Berit Müller,Scarlet Brockmöller,Tuulikki Seppänen-Laakso,Jan Budczies,Elmar Bucher,Laxman Yetukuri,Sandra Castillo, Emilia Berg,Heli Nygren,
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