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职业迁徙
个人简介
Petra Sipilä completed her PhD at the Department of Biomedicine, University of Turku, Finland (2003) and continued for post-doctoral training first at Professor Andrew McMahon’s lab at Molecular and Cellular Biology, Harvard University and then as Finnish Academy Postdoctoral Researcher at the University of Turku. In 2007 she was appointed as Coordinator for GM unit at Turku Center for Disease Modeling (TCDM) and in 2012 as a director of GM unit at the Laboratory Animal Centre of University of Helsinki. Since spring 2015 she has been a principal investigator at the UTU Research Faculty of Medicine, University of Turku and Vice director of Turku Center for Disease modeling (TCDM) at the University of Turku.
Her research focuses on unraveling how tissue-specific androgen responses are mediated via androgen receptor SUMOylation, pioneer factors, collaborating transcription factors and microRNAs in the epididymis and further demonstrating the importance of those regulators for epididymal sperm maturation and male fertility.
Sipilä lab is also part of the FinnDisMice research consortium, that is committed to utilize CRISPR/Cas9 genome editing to generate disease models for several rare diseases of the Finnish disease heritage, which contains almost forty monogenic, rare hereditary diseases that are clearly enriched in Finland. The special phenotyping focus of our group is in cartilage-hair hypoplasia, a disease manifested by growth disorder and defective immune system.
研究兴趣
论文共 67 篇作者统计合作学者相似作者
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ANDROLOGY (2024)
Madhukar Vedantham,Lauri Polari, Anbu Poosakkannu, Rita G Pinto,Moona Sakari, Jukka Laine,Petra Sipila,Jorma Maatta,Heidi Gerke, Tiia M Rissanen,Pia Rantakari,Diana M Toivola,
biorxiv(2024)
Mervi Toriseva,Ida Björkgren, Arttu Junnila,Arfa Mehmood,Jesse Mattsson, Inka Raimoranta,Bongki Kim,Asta Laiho,Matthias Nees,Laura Elo,Matti Poutanen,Sylvie Breton,
Cellular and Molecular Life Sciencesno. 1 (2024): 1-21
Endocrinologyno. 6 (2024)
TRANSGENIC RESEARCH (2023): S3-S3
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FASEB bioAdvancesno. 5 (2023): 183-198
FASEB BIOADVANCESno. 5 (2023): 183-198
Journal of the Endocrine Societyno. Supplement_1 (2023)
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