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个人简介
Allan Bradley is a geneticist who has made fundamental contributions to our understanding of embryonic stem (ES) cells and DNA manipulation. Allan’s experiments have opened up a new line of research for biologists based on techniques for modifying endogenous genes in mice.
He was first to demonstrate that following injection into pre-implantation blastocysts, ES cells can be transmitted through the sperm and eggs of the resulting mice. Allan later reported that such techniques could be used to generate mice containing specific gene mutations — work that contributed to the 2007 Nobel Prize in Physiology or Medicine.
From 2000–2010, Allan served as Director of the Wellcome Trust Sanger Institute in Cambridge. During this time, he established a new direction for the institute and initiated the largest gene knockout project ever attempted on ES cells. In 1994, he received the DeBakey Award of Baylor College of Medicine for his work on chromosome engineering in ES cells.
研究兴趣
论文共 512 篇作者统计合作学者相似作者
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biorxiv(2024)
Cell Genomicsno. 3 (2023): 100276-100276
Cell metabolismno. 1 (2022): 106-124.e10
Jonah N Cullen, Jolyon Martin,Albert J Vilella,Amy Treeful,David Sargan,Allan Bradley,Steven G Friedenberg
biorxiv(2022)
Marc Janier,Mohammed Almadjub, Olivier Beuf, Claire Billotey, Radu Bolbos, Laurence Canaple,Emmanuel Chereul,Denis Grenier,Bassem Hiba, Christophe Odet, Jean-Baptiste Langlois,Carole Lartizien,
Chiara Falcomatà,Stefanie Bärthel,Angelika Ulrich,Sandra Diersch,Christian Veltkamp,Lena Rad,Fabio Boniolo, Myriam Solar,Katja Steiger,Barbara Seidler,Magdalena Zukowska, Joanna Madej,
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