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Research in my lab is aimed at understanding mechanisms underlying cell structure and shape in health and disease. I focus on the role of the microtubule (MT) cytoskeleton and on a group of proteins, called MT plus-end tracking proteins (+TIPs), which specifically associate with the ends of growing MTs. I also study a nuclear factor, called CTCF, that organizes chromatin. Research in the last 5 years brings together these seemingly different subjects, as we are deciphering cytoplasmic interaction networks that coordinate signalling from the plasma membrane to the nucleus and back. Thus, we are slowly starting to understand the molecular players that link MT mechanics to signalling and transcription, and that ultimately regulate cell shape.
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论文共 153 篇作者统计合作学者相似作者
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REPRODUCTIVE SCIENCES (2023): 99A-99A
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FASEB journal : official publication of the Federation of American Societies for Experimental Biologyno. 8 (2023)
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CARDIOVASCULAR RESEARCHno. 7 (2023): 1461-1479
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Teruyoshi Hirayama, Yuuki Kadooka,Etsuko Tarusawa,Sei Saitoh,Hisako Nakayama,Natsumi Hoshino, Soichiro Nakama, Takahiro Fukuishi, Yudai Kawanishi,Hiroki Umeshima,Koichi Tomita,Yumiko Yoshimura,
Teruyoshi Hirayama, Kadooka Yuuki,Etsuko Tarusawa,Sei Saito,Hisako Nakayama,Natsumi Hoshino, Soichiro Nakama, Takahiro Fukuishi, Yudai Kawanishi,Hiroki Umeshima,Koichi Tomita,Yumiko Yoshimura,
Research Square (Research Square) (2022)
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