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个人简介
My research focuses on developing and using new experimental methodologies that enable unprecedented quantitative insight into the states and structures that proteins adopt. In our group, we integrate the data we gather using these new techniques with computational strategies, incorporating evolutionary history and measurements of cellular activity to uncover the physico-chemical determinants of biomolecular function.
To overcome the structural heterogeneity frequently displayed by proteins and their complexes, we exploit the separative capabilities of mass spectrometry to probe and manipulate individual states—both at, and away from, equilibrium. This has allowed us to gain valuable insights into the processes of molecular recognition, and the regulation of protein interactions.
To overcome the structural heterogeneity frequently displayed by proteins and their complexes, we exploit the separative capabilities of mass spectrometry to probe and manipulate individual states—both at, and away from, equilibrium. This has allowed us to gain valuable insights into the processes of molecular recognition, and the regulation of protein interactions.
研究兴趣
论文共 158 篇作者统计合作学者相似作者
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Zihao Wang, Guodong Cao,Miranda P Collier,Xingyu Qiu,Sophie Broadway-Stringer,Dominik Saman, Jediael ZY NG, Navoneel Sen,Amar J Azad, Charlotte Hooper,Johannes Zimmermann,Michael McDonough,
biorxiv(2024)
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Luka Kavčič, Andreja Kežar, Neža Koritnik,Magda Tušek Žnidarič, Tajda Klobučar, Žiga Vičič,Franci Merzel, Ellie Holden,Justin L. P. Benesch,Marjetka Podobnik
Communications Chemistryno. 1 (2024): 1-19
Structure (2024)
Franziska L. Sendker, Yat Kei Lo,Thomas Heimerl, Stefan Bohn, Louise J. Persson,Christopher-Nils Mais, Wiktoria Sadowska,Nicole Paczia, Eva Nussbaum, Maria del Carmen Sanchez Olmos,Karl Forchhammer,Daniel Schindler,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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biorxiv(2023)
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Cell stress & chaperonesno. 6 (2023): 621-629
Luka Kavcic, Andreja Kezar, Neza Koritnik, Magda Tusek-Znidaric,Franci Merzel, Elena Holden,Justin L. P. Benesch
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERSno. SUPPL 1 (2023): S88-S88
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Nature Ecology & Evolutionno. 5 (2023): 756-767
biorxiv(2023)
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